[1]张琪 宋晓鹏 任茂佳 吴广 赵兴胜.氧化三甲胺与心血管疾病的研究新进展[J].心血管病学进展,2020,(1):81-84.[doi:10.16806/j.cnki.issn.1004-3934.2020.01.022]
 ZHANG Qi,SONG Xiaopeng,REN Maojia,et al.Trimethylamine Oxide and Cardiovascular Diseases[J].Advances in Cardiovascular Diseases,2020,(1):81-84.[doi:10.16806/j.cnki.issn.1004-3934.2020.01.022]
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氧化三甲胺与心血管疾病的研究新进展()
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《心血管病学进展》[ISSN:51-1187/R/CN:1004-3934]

卷:
期数:
2020年1期
页码:
81-84
栏目:
综述
出版日期:
2020-02-04

文章信息/Info

Title:
Trimethylamine Oxide and Cardiovascular Diseases
作者:
张琪1 宋晓鹏 2 任茂佳 2 吴广 3 赵兴胜3
(1.内蒙古科技大学包头医学院 内蒙古临床医学院,内蒙古 呼和浩特 010017;2.内蒙古医科大学 内蒙古临床医学院,内蒙古 呼和浩特 010017;3.内蒙古自治区人民医院心脏中心,内蒙古 呼和浩特 010017)
Author(s):
ZHANG QiSONG XiaopengREN MaojiaWU GuangZHAO Xingsheng
(1.Baotou Medical College,Inner Mongolia University of Science and Technology,Inner Mongolia Clinical Medical College,Hohhot 010017,Inner Mongolia,China; 2.Inner Mongolia Clinical Medical College,Inner Mongolia Medical University,Hohhot 010017,Inner Mongolia,China; 3.Heart Center,Inner Mongolia People’s Hospital,Hohhot 010017,Inner Mongolia,China)
关键词:
氧化三甲胺心血管疾病肠道菌群
Keywords:
Trimethylamine oxideCardiovascular diseasesIntestinal flora
DOI:
10.16806/j.cnki.issn.1004-3934.2020.01.022
摘要:
越来越多的证据表明,肠道菌群结构紊乱与心血管疾病的发生密切相关。氧化三甲胺作为肠道菌群的代谢产物,在心血管疾病的发生发展中起着重要作用。现就氧化三甲胺与冠心病、心力衰竭、高血压、心房颤动和心肌纤维化的关系及其可能的机制做一综述,为心血管疾病的防治提供新靶点。
Abstract:
More and more evidences show that intestinal flora disorders are closely related to the occurrence of cardiovascular diseases.Trimethylamine oxide, as the metabolite of intestinal flora ,plays an important role in the occurrence and development of cardiovascular diseases.This article reviews the relationship between trimethylamine oxide and coronary heart disease,heart failure,hypertension,atrial fibrillation and myocardial fibrosis,and its possible mechanism,so as to provide a new target for the prevention and treatment of cardiovascular diseases.

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备注/Memo

备注/Memo:
基金项目:内蒙古自治区自然科学基金项目(2018MS08065)
通讯作者:赵兴胜,E-mail:zhaoxs1121@163.com
更新日期/Last Update: 2020-03-24