[1]张维 张恒 康品方.外泌体在心血管疾病中的研究进展[J].心血管病学进展,2019,(5):818-821.[doi:10.16806/j.cnki.issn.1004-3934.2019.05.038]
 Zhang WeiKang Pinfang.Exosome in Cardiovascular Diseases[J].Advances in Cardiovascular Diseases,2019,(5):818-821.[doi:10.16806/j.cnki.issn.1004-3934.2019.05.038]
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外泌体在心血管疾病中的研究进展()
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《心血管病学进展》[ISSN:51-1187/R/CN:1004-3934]

卷:
期数:
2019年5期
页码:
818-821
栏目:
综述
出版日期:
2019-08-25

文章信息/Info

Title:
Exosome in Cardiovascular Diseases
作者:
张维 张恒 康品方
(1.蚌埠医学院第一附属医院心血管内科,安徽 蚌埠 233600)
Author(s):
Zhang WeiKang Pinfang
(Department of CardiologyFirst Affiliated Hospital of Bengbu Medical CollegeBengbu 233600AnhuiChina)
关键词:
外泌体心血管疾病miRNA胞外囊泡
Keywords:
ExosomeAngiocardiopathymiRNAExtracellular vesicles
DOI:
10.16806/j.cnki.issn.1004-3934.2019.05.038
摘要:
外泌体是细胞经过包吞方式,分泌到细胞外的一种囊泡结构。其内含有多种蛋白质、核酸等具有生物活性的物质,介导机体内多种生理活动,包括免疫调节、炎症反应、基因转递、细胞间交流等。另一方面,心血管疾病仍居我国居民死亡率首位,严重影响着全体居民的健康生活。越来越多的研究表明,外泌体在心力衰竭、急性心肌梗死、高血压等疾病中有着重要的作用,介导疾病的发生发展,影响疾病的进展,并在一些疾病中有望作为更加精准的疾病标志物。现从多个方面介绍外泌体在心血管疾病的研究进展。
Abstract:
Exosome body is a vesicular structure which is secreted by cells through the way of ingestion. It contains a variety of proteins, nucleic acids and other bioactive substances, mediating a variety of physiological activities in the body, including immune regulation, inflammatory response, gene transmission, intercellular communication,nd so on. On the other hand, cardiovascular disease still ranks first in the mortality rate, which seriously affects the healthy life of the whole population. More and more studies have shown that exosome body plays an important role in heart failure, acute myocardial infarction, hypertension and other diseases, mediating the occurrence and development of disease, affecting the progress of disease. And in some diseases are expected to be more accurate disease markers. This article will introduce the research progress of exosome in cardiovascular disease

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更新日期/Last Update: 2019-12-25