[1]邱明仙 王正龙 许官学.心肌肌球蛋白结合蛋白-C磷酸化与心血管疾病关系的研究进展[J].心血管病学进展,2019,(7):1015-1018.[doi:10.16806/j.cnki.issn.1004-3934.2019.07.013]
 QIU MingxianWANG ZhenglongXU Guanxue.Research Progress of the Relationship Between Cardiac Myosin Binding Protein-C and Cardiovascular Disease[J].Advances in Cardiovascular Diseases,2019,(7):1015-1018.[doi:10.16806/j.cnki.issn.1004-3934.2019.07.013]
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心肌肌球蛋白结合蛋白-C磷酸化与心血管疾病关系的研究进展()
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《心血管病学进展》[ISSN:51-1187/R/CN:1004-3934]

卷:
期数:
2019年7期
页码:
1015-1018
栏目:
综述
出版日期:
2019-10-25

文章信息/Info

Title:
Research Progress of the Relationship Between Cardiac Myosin Binding Protein-C and Cardiovascular Disease
作者:
邱明仙1 王正龙2 许官学12
(1. 遵义医科大学,贵州 遵义 563003 ;2.遵义医科大学附属第一医院心血管内科,贵州 遵义 563000 )
Author(s):
QIU Mingxian1WANG Zhenglong2XU Guanxue12
(1.Zunyi Medical UniversityZunyi 563003GuizhouChina2.Department of CardiologyThe First Affiliated Hospital of Zunyi Medical UniversityZunyi 563000GuizhouChina)
关键词:
心肌肌球蛋白结合蛋白-C心血管疾病
Keywords:
Cardiac myosin binding protein-CCardiovascular disease
DOI:
10.16806/j.cnki.issn.1004-3934.2019.07.013
摘要:
心肌肌球蛋白结合蛋白-C是心肌纤维的组成部分,它的磷酸化对保护心肌细胞及调节心肌收缩舒张功能起着重要作用。心肌肌球蛋白结合蛋白-C具有多个磷酸化位点,特异性表达于哺乳动物心肌中。近年来研究发现其与心肌梗死、心力衰竭、心肌病等心血管疾病的发生、发展密切相关。现就心肌肌球蛋白结合蛋白-C与心血管疾病关系的研究进展做一综述。
Abstract:
Cardiac myosin binding protein-C is a component of myocardial fibers, and its phosphorylation plays an important role in protecting cardiomyocytes and regulating myocardial systolic and diastolic function.Cardiac myosin binding protein-C has multiple phosphorylation sites and is specifically expressed in mammalian myocardium.In recent years, studies have found that it is closely related to the occurrence and development of cardiovascular diseases such as myocardial infarction, heart failure and cardiomyopathy.This article reviews the research progress of the relationship between cardiac myosin binding protein-C and cardiovascular diseases

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更新日期/Last Update: 2019-12-16