[1]郭辅定 殷铭 赖燕秋 江洪.蒽环类药物相关心血管疾病与自主神经调控展望[J].心血管病学进展,2021,(3):248-251.[doi:10.16806/j.cnki.issn.1004-3934.20 21.03.014]
 GUO Fuding,YIN Ming,LAI Yanqiu,et al.Anthracycline-induced Cardiovascular Diseases and Autonomic Nervous Regulation[J].Advances in Cardiovascular Diseases,2021,(3):248-251.[doi:10.16806/j.cnki.issn.1004-3934.20 21.03.014]
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蒽环类药物相关心血管疾病与自主神经调控展望()
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《心血管病学进展》[ISSN:51-1187/R/CN:1004-3934]

卷:
期数:
2021年3期
页码:
248-251
栏目:
出版日期:
2021-03-25

文章信息/Info

Title:
Anthracycline-induced Cardiovascular Diseases and Autonomic Nervous Regulation
作者:
郭辅定 殷铭 赖燕秋 江洪
(武汉大学人民医院心内科 武汉大学心脏自主神经研究中心 武汉大学心血管病研究所 心血管病湖北省重点实验室,湖北 武汉430060)
Author(s):
GUO Fuding YIN Ming LAI Yanqiu JIANG Hong
(Department of Cardiology,Renmin Hospital of Wuhan University;Cardiac Autonomic Nervous Research Center,Wuhan University;Cardiovascular Research Institute,Wuhan University;Hubei Key Laboratory of Cardiology;Wuhan 430060,Hubei,China)
关键词:
蒽环类药物心血管疾病自主神经系统发病机制
Keywords:
AnthracyclineCardiovascular disease sAutonomic nervous systemPathogenesis
DOI:
10.16806/j.cnki.issn.1004-3934.20 21.03.014
摘要:
蒽环类药物是临床实践中广泛使用的有效抗肿瘤药物,然而蒽环类药物相关心脏毒性副作用很大程度上限制了其临床应用。心脏自主神经系统紊乱参与了多种心血管疾病的发生和发展,通过调控自主神经实现再平衡可用于治疗心血管疾病。研究表明,蒽环类药物的使用与心脏自主神经失平衡密切相关。现就蒽环类药物相关心血管疾病及自主神经调控防治蒽环类药物相关心脏毒性的潜在机制进行综述,为临床防治蒽环类药物相关心血管疾病提供新思路。
Abstract:
Anthracyclines are effective anti-cancer drugs extensively used in clinical practice. However,the side effects of anthracycline-related cardiotoxicity have strongly influenced its clinical use. The cardiac autonomic nervous system disorders are involved in the occurrence and development of various cardiovascular diseases,and the regulation of autonomic nerve rebalance can be used in the treatment of cardiovascular diseases. Studies have shown that the use of anthracyclines is closely related to cardiac autonomic nervous imbalance. This article reviews the anthracycline-induced cardiovascular diseases and potential mechanisms of autonomic nervous regulation prevention and treatment of anthracycline-related cardiotoxicity,provid ing new ideas for clinical prevention and treatment of anthracycline-related cardiovascular disease s

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更新日期/Last Update: 2021-05-27