参考文献/References:
[1] Mcpherson R,Tybjaerg-hansen A. Genetics of coronary artery disease[J]. Circulation research,2016,118(4):564-578.
[2] Schulz S,Seitter L,Werdan K,et al. Single nucleotide polymorphisms in long noncoding RNA,ANRIL,are not associated with severe periodontitis but with adverse cardiovascular events among patients with cardiovascular disease[J] J periodontal res ,2018,53(5):714-720.
[3] Kong Y,Hsieh CH,Alonso LC. ANRIL:A lncRNA at the CDKN2A/B Locus with roles in cancer and metabolic disease[J]. Frontiers in endocrinology,2018,24(9):405.
[4] Holdt L M,Teupser D. Long noncoding RNA ANRIL:lnc-ing genetic variation at the chromosome 9p21 locus to molecular mechanisms of atherosclerosis[J]. Front cardiovasc med,2018,6(5):145.
[5] Kong Y,Sharma RB,Ly S,et al. CDKN2A/B T2D genome-wide association study risk SNPs impact locus gene expression and proliferation in human islets[J]. Diabetes,2018,67(5):872-884.
[6] Liu J,Yan J,Li Y,et al. Progress in genetic research on familiar aneurysms[J]. Zhong Nan Da Xue Xue Bao Yi Xue Ban,2019,44(3):338-344.
[7] Miao JT,Gao JH,Chen YQ,et al. LncRNA ANRIL affects the sensitivity of ovarian cancer to cisplatin via regulation of let-7a/HMGA2 axis[J]. Biosci Rep,2019,39(7):BSR20182101.
[8] Hubberten M,Bochenek G,Chen H,et al. Linear isoforms of the long noncoding RNA CDKN2B-AS1 regulate the c-myc-enhancer binding factor RBMS1[J]. Eur J Human Genet,2019,27(1):80-89.
[9] Taiete T,Casati MZ,Stolf CS,et al. Validation of reported GLT6D1(rs1537415),IL10 (rs6667202),and ANRIL(rs1333048) single nucleotide polymorphisms for aggressive periodontitis in a Brazilian population[J]. J Periodontol,2019,90(1):44-51.
[10] Fortney K,Dobriban E,Garagnani P,et al. Genome-Wide Scan Informed by Age-Related Disease Identifies Loci for Exceptional Human Longevity[J]. PLoS Genet,2015,11(12):e1005728.
[11] Nakaoka H,Gurumurthy A,Hayano T,et al. Allelic Imbalance in Regulation of ANRIL through Chromatin Interaction at 9p21 Endometriosis Risk Locus[J]. PLoS Genet,2016,12(4):e1005893.
[12] Zhao J,Sun H,Zhang J M,et al. Long non-coding RNA ANRIL down-regulates microRNA-7 to protect human trabecular meshwork cells in an experimental model for glaucoma[J]. Eur Rev Med Pharmacol Sci,2019,23(8):3173-3182.
[13]Sarkar D,Oghabian A,Bodiyabadu PK,et al. Multiple isoforms of ANRIL in melanoma cells:structural complexity suggests variations in processing[J]. Int J Mol Sci ,2017,18(7):E1378.
[14]Barrett SP,Salzman J. Circular RNAs:analysis,expression and potential functions[J]. Development,2016,143(11):1838-1847.
[15]Holdt L M,Stahringer A,Sass K,et al. Circular non-coding RNA ANRIL modulates ribosomal RNA maturation and atherosclerosis in humans[J]. Nat Commun,2016,19(7):12429.
[16]Rodriguez C,Borgel J,Court F,et al. CTCF is a DNA methylation-sensitive positive regulator of the INK/ARF locus[J]. Biochem Biophys Res Commun,2010,392(2):129-134.
[17] Lillycrop K,Murray R,Cheong C,et al. ANRIL promoter DNA methylation:a perinatal marker for later adiposity[J]. EBioMedicine,2017,19:60-72.
[18] Curtis EM,Murray R,Titcombe P,et al. Perinatal DNA methylation at CDKN2A is associated with offspring bone mass:findings from the Southampton Women’s Survey[J]. JBone?Miner Res,2017,32(10):2030-2040.
[19] Gan Y,Ma W,Wang X,et al. Coordinated transcription of ANRIL and P16 genes is silenced by P16 DNA methylation[J]. Chin J Cancer Res,2018,30(1):93-103.
[20] Yang Y,Peng X W. The silencing of long non-coding RNA ANRIL suppresses invasion,and promotes apoptosis of retinoblastoma cells through the ATM-E2F1 signaling pathway[J]. Biosci Rep ,2018,38(6):BSR20180558.
[21]Lu Y,Zhou X,Xu L,et al. Long noncoding RNA ANRIL could be transactivated by c-Myc and promote tumor progression of non-small-cell lung cancer[J]. Onco Targets Ther ,2016,24(9):3077-3084.
[22]Wu JH,Tang JM,Li J,et al. Upregulation of SOX2-activated lncRNA ANRIL promotes nasopharyngeal carcinoma cell growth[J]. Sci Rep ,2018,8(1):3333.
[23]Huang MD,Chen WM,Qi FZ,et al. Long non-coding RNA ANRIL is upregulated in hepatocellular carcinoma and regulates cell apoptosis by epigenetic silencing of KLF2[J]. J Hematology Oncol,2015,14(8):50.
[24]Deng W,Wang J,Zhang J,et al. TET2 regulates LncRNA-ANRIL expression and inhibits the growth of human gastric cancer cells[J]. IUBMB Life,2016,68(5):355-364.
[25]Kotake Y,Naemura M,Kitagawa K,et al. Oncogenic Ras influences the expression of multiple lncRNAs[J]. Cytotechnology,2016,68(4):1591-1596.
[26]Ge Q,Dong Y,Lin G,et al. Long noncoding RNA antisense noncoding RNA in the INK4 locus correlates with risk,severity,inflammation and infliximab efficacy in Crohn’s disease[J]. Am J Med Sci ,2019,357(2):134-142.
[27]Meseure D,Vacher S,Alsibai KD,et al. Expression of ANRIL-polycomb complexes-CDKN2A/B/ARF genes in breast tumors:identification of a two-gene(EZH2/CBX7) signature with independent prognostic value[J]. Mol Cancer Res,2016,14(7):623-633.
[28]Lavarone E,Barbieri CM,Pasini D. Dissecting the role of H3K27 acetylation and methylation in PRC2 mediated control of cellular identity[J]. Nat Commun,2019,10(1):1679.
[29]Townsend N,Wilson L,Bhatnagar P,et al. Cardiovascular disease in Europe:epidemiological update 2016[J]. E Heart J,2016,37(42):3232-3245.
[30] Libby P,Bornfeldt KE,Tall AR. Atherosclerosis:Successes,Surprises,and Future Challenges[J]. Circ Res ,2016,118(4):531-534.
[31]Nie FQ,Sun M,Yang JS,et al. Long noncoding RNA ANRIL promotes non-small cell lung cancer cell proliferation and inhibits apoptosis by silencing KLF2 and P21 expression[J]. MolCancer?Ther,2015,14(1):268-277.
[32]Broadbent HM,Peden JF,Lorkowski S,et al. Susceptibility to coronary artery disease and diabetes is encoded by distinct,tightly linked SNPs in the ANRIL locus on chromosome 9p[J]. Hum Mol Genet,2008,17(6):806-814.
[33]Kojima Y,Downing K,Kundu R,et al. Cyclin-dependent kinase inhibitor 2B regulates efferocytosis and atherosclerosis[J]. J Clin Invest,2014,124(3):1083-1097.
[34] Kuo CL,Murphy AJ,Sayers S,et al. Cdkn2a is an atherosclerosis modifier locus that regulates monocyte/macrophage proliferation[J]. Arterioscler Thromb Vasc Biol,2011,31(11):2483-2492.
[35]Song CL,Wang JP,Xue X,et al. Effect of circular ANRIL on the Inflammatory response of vascular endothelial cells in a rat model of coronary atherosclerosis[J]. Cell Physiol Biochem.,2017,42(3):1202-1212.
[36]郭君君,郑宏超,曹阳.生物标志物对急性心肌梗死介入治疗预后的预测意义[J]. 心血管病学进展,2016,37(1):37-41.
[37]Cheng J,Cho M,Cen JM,et al. A TagSNP in SIRT1 gene confers susceptibility to myocardial infarction in a Chinese Han population[J]. PloS One,2015,10(2):e0115339.
[38] Li Y,Zhang D,Zhang Y,et al. Association of lncRNA polymorphisms with triglyceride and total cholesterol levels among myocardial infarction patients in Chinese population[J]. Gene,2019,724:S0378-1119(19)30249-5.
[39]Cheng J,Cai MY,Chen YN,et al. Variants in ANRIL gene correlated with its expression contribute to myocardial infarction risk[J]. Oncotarget,2017,8(8):12607-12619.
[40]Haslacher H,Perkmann T,Ratzinger F,et al. 9p21.3 risk locus is associated with first-ever myocardial infarction in an Austrian cohort[J]. J Cardiovasc Med (Hagerstown) ,2016,17(8):595-600.
[41]Vausort M,Wagner DR,Devaux Y. Long noncoding RNAs in patients with acute myocardial infarction[J]. Circ Res,2014,115(7):668-677.
[42]Oh J ,Kang S M,Kim I C,et al. The beneficial prognostic value of hemoconcentration is negatively affected by hyponatremia in acute decompensated heart failure:Data from the Korean Heart Failure(KorHF) Registry[J]. J Cardiol ,2017,69(5):790-796.
[43]Fu T C,Lin Y C,Chang C M,et al. Validation of a new simple scale to measure symptoms in heart failure from traditional Chinese medicine view:a cross-sectional questionnaire study[J]. BMC Complement Altern Med ,2016,2(16):342.
[44]费民忠,陈玲玲,张美玲,等. 位于细胞周期激酶抑制因子4基因座中反义非编码RNA在慢性心力衰竭患者血清中的表达及临床意义[J]. 中国循环杂志 2017 ,32(11):1095-1098.
[45]Greco S ,Zaccagnint G ,Perfetti A ,et al. Long noncoding RNA dysregulation in ischemic heart failure[J]. J Transl Med,2016,14(1):183.