[1]张馨月 涂荣会.Toll样受体与心肌缺血再灌注损伤及其保护作用研究进展[J].心血管病学进展,2020,(2):172-175.[doi:10.16806/j.cnki.issn.1004-3934.2020.02.018]
 ZHANG Xinyue,TU Ronghui.Review Onprotective Effects of Toll-like Receptors on Myocardial Ischemia Reperfusion Injury[J].Advances in Cardiovascular Diseases,2020,(2):172-175.[doi:10.16806/j.cnki.issn.1004-3934.2020.02.018]
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Toll样受体与心肌缺血再灌注损伤及其保护作用研究进展()
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《心血管病学进展》[ISSN:51-1187/R/CN:1004-3934]

卷:
期数:
2020年2期
页码:
172-175
栏目:
综述
出版日期:
2020-02-25

文章信息/Info

Title:
Review Onprotective Effects of Toll-like Receptors on Myocardial Ischemia Reperfusion Injury
作者:
张馨月 涂荣会
 (广西医科大学第一附属医院心内科, 广西 南宁 530021)
Author(s):
ZHANG XinyueTU Ronghui
(Department of Cardiology, First Afiliated Hospital , Medical University, Nanning 530021,Guangxi,China)
关键词:
Toll样受体心肌缺血再灌注损伤缺血预处理缺血后处理
Keywords:
Toll-like receptor Myocardial ischemia-reperfusion injury Ischemic preconditioning Ischemic postconditioning
DOI:
10.16806/j.cnki.issn.1004-3934.2020.02.018
摘要:
早期及时的再灌注是治疗心肌缺血的关键,然而随之带来的心律失常及心脏功能障碍等,直接影响患者的预后。缺血预处理和缺血后处理是目前最强的两种心肌内源性保护方法,在缺血性心肌保护中受到广泛关注。研究显示 Toll样受体信号通路在心肌缺血再灌注损伤、缺血预处理和缺血后处理心脏保护方面起着重要调控作用。现就Toll样受体与心脏缺血再灌注损伤及其保护作用的研究进展予以综述。
Abstract:
Early and timely reperfusion is the key to the treatment of myocardial ischemia, but the following arrhythmia and cardiac dysfunction, directly affect the prognosis of patients. Ischemic preconditioning and ischemic postconditioning are currently the two strongest methods of endogenous protection of the myocardium, which have drawedextensive attention. Researches showed that the Toll-like receptor signaling pathway played an important regulatory role in myocardial ischemia-reperfusion injury as well as ischemic preconditioningand postconditioning. This article reviews current researches on the protective effects of Toll-like receptors on myocardial ischemia-reperfusion injury

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更新日期/Last Update: 2020-04-14