[1]孟雅洁,综述,付真彦,等.芳香化酶基因与心血管相关疾病的研究进展[J].心血管病学进展,2016,(4):405-408.[doi:10.16806/j.cnki.issn.1004-3934.2016.04.020]
 MENG Yajie,FU Zhenyan.Progress in Research of the Relationship Between CYP19A1 Gene and Cardiovascular Disease[J].Advances in Cardiovascular Diseases,2016,(4):405-408.[doi:10.16806/j.cnki.issn.1004-3934.2016.04.020]
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芳香化酶基因与心血管相关疾病的研究进展()
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《心血管病学进展》[ISSN:51-1187/R/CN:1004-3934]

卷:
期数:
2016年4期
页码:
405-408
栏目:
综述
出版日期:
2016-08-15

文章信息/Info

Title:
Progress in Research of the Relationship Between CYP19A1 Gene and Cardiovascular Disease
作者:
孟雅洁综述付真彦审校
新疆医科大学第一附属医院心脏中心,新疆 乌鲁木齐 830054
Author(s):
MENG Yajie FU Zhenyan
Heart Center,The First Affiliated Hospital of Xinjiang Medical University,Urumqi 830054,Xinjiang,China
关键词:
芳香化酶基因 心血管疾病 单核苷酸多态性
Keywords:
CYP19A1 gene Cardiovascular disease Single nucleotide polymorphism
分类号:
R54
DOI:
10.16806/j.cnki.issn.1004-3934.2016.04.020
文献标志码:
A
摘要:
芳香化酶基因位于15q21,包含有10 个外显子和9个内含子,是体内催化雄激素向雌激素转化的一个关键酶,对雌和雄激素在体内的平衡有着重要的作用。近年来研究发现,芳香化酶基因与某些心血管疾病有关联。现对该基因与心血管相关疾病做一综述。
Abstract:
The CYP19A1 gene is located on chromosome15q21 and consists of ten exons and nine introns. It is a key enzyme for catalyzing androgen into estrogen and plays an important role in balancing both estrogen and androgen in the body. Recently studies have found that the CYP19A1 gene is associated with cardiovascular disease.The present study reviews research that discusses the relationship between the CYP19A1 gene and cardiovascular diseases.

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备注/Memo

备注/Memo:
作者简介:孟雅洁(1990—),硕士,主要从事冠心病遗传学与分子生物学研究。Email:mengyajie1105@163.com 通信作者:付真彦(1973—),主任医师,教授,硕士研究生导师,主要从事冠心病遗传学与分子生物学研究。Email:fuzhenyan316@126.com
更新日期/Last Update: 2016-07-25