[1]冉丹,佘强.载脂蛋白C-Ⅲ在心血管疾病中的研究进展[J].心血管病学进展,2015,(5):613-615.[doi:10.3969/j.issn.1004-3934.2015.05.023]
 RAN Dan,SHE Qiang.Progress of Apolipoprotein C-Ⅲ in Cardiovascular Diseases[J].Advances in Cardiovascular Diseases,2015,(5):613-615.[doi:10.3969/j.issn.1004-3934.2015.05.023]
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载脂蛋白C-Ⅲ在心血管疾病中的研究进展()
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《心血管病学进展》[ISSN:51-1187/R/CN:1004-3934]

卷:
期数:
2015年5期
页码:
613-615
栏目:
综述
出版日期:
2016-05-20

文章信息/Info

Title:
Progress of Apolipoprotein C-Ⅲ in Cardiovascular Diseases
作者:
冉丹佘强
重庆医科大学附属第二医院心血管内科, 重庆 400001
Author(s):
RAN DanSHE Qiang
Department of Cardiology,The Second Affiliated Hospital of Chongqing Medical University,Chongqing 400001,China
关键词:
载脂蛋白C-Ⅲ 血脂调节 心血管疾病
Keywords:
apolipoprotein C-Ⅲ lipid regulation cardiovascular disease
分类号:
R54
DOI:
10.3969/j.issn.1004-3934.2015.05.023
文献标志码:
A
摘要:
血脂异常会导致心血管疾病风险增加,降脂可减少动脉粥样硬化及其并发症的发生发展。他汀类药物能有效降低低密度脂蛋白,然而,许多患者在低密度脂蛋白很低的情况下仍发生心血管事件,载脂蛋白C-Ⅲ有直接导致动脉粥样硬化的作用,促发炎症因子的表达释放,是心血管疾病独立危险因素,因而载脂蛋白C-Ⅲ抑制剂为心血管疾病的治疗提供新的干预方式。
Abstract:
Dyslipidemia can increase the risk of cardiovascular disease, and lowering lipids may reduce the development of atherosclerosis and its complications. Statins can reduce low density lipoprotein, however, many patients with cardiovascular events still occur with cases of low density lipoprotein. Apolipoprotein C-Ⅲ has a direct role in causing atherosclerosis, and it can prove the release of inflammatory factors. Also, it is an independent risk factor for cardiovascular disease. Thus apolipoprotein C-Ⅲ inhibitors provide new interventions for the treatment of cardiovascular diseases.

参考文献/References:

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备注/Memo

备注/Memo:
作者简介:冉丹(1989—),医师,硕士在读,主要从事冠心病与血脂的临床研究。Email:randan89@sina.com
更新日期/Last Update: 2016-05-20