[1]伊卜拉伊木·热合曼 郭衍楷 汤宝鹏.白细胞介素11在心血管疾病中的研究进展[J].心血管病学进展,2025,(9):811.[doi:10.16806/j.cnki.issn.1004-3934.2025.09.010]
 Yibulayimu·Reheman,GUO Yankai,TANG Baopeng.Interleukin-11 in Cardiovascular Diseases[J].Advances in Cardiovascular Diseases,2025,(9):811.[doi:10.16806/j.cnki.issn.1004-3934.2025.09.010]
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白细胞介素11在心血管疾病中的研究进展()

《心血管病学进展》[ISSN:51-1187/R/CN:1004-3934]

卷:
期数:
2025年9期
页码:
811
栏目:
综述
出版日期:
2025-09-25

文章信息/Info

Title:
Interleukin-11 in Cardiovascular Diseases
作者:
伊卜拉伊木·热合曼 郭衍楷 汤宝鹏
(新疆医科大学第一附属医院心脏起搏电生理科,新疆 乌鲁木齐 830000)
Author(s):
Yibulayimu·RehemanGUO YankaiTANG Baopeng
(Department of cardiac pacing Eletrophysiology,The First Affiliated Hospital of Xinjiang Medical University,Urumqi 830000,Xinjiang,China)
关键词:
白细胞介素11心血管疾病纤维化炎症反应氧化应激
Keywords:
Interleukin-11Cardiovascular diseasesFibrosisInflammationOxidative stress
DOI:
10.16806/j.cnki.issn.1004-3934.2025.09.010
摘要:
白细胞介素(IL)-11隶属于IL-6家族,虽与IL-6结构存在差异,但其功能联系紧密。近年来,研究发现IL-11在心血管疾病的发生、心脏纤维化及重构进程中占据关键地位,极有可能成为心血管疾病治疗的崭新靶点。现全面综述IL-11与心血管疾病之间的相互作用、作用机制、研究进展,并对其未来发展趋向进行了前瞻性探讨,旨在为临床治疗提供有价值的参考依据。
Abstract:
Interleukin (IL)-11 belongs to the IL-6 family. Although there are differences in structure from IL-6,its functions are closely related. In recent years,studies have found that IL-11 plays a crucial role in the occurrence of cardiovascular diseases,cardiac fibrosis and the process of remodeling,and it is highly likely to become a new target for the treatment of cardiovascular diseases. This review comprehensively summarizes the interactions between IL-11 and cardiovascular diseases, their mechanisms of action, research progress, and provides a forward-looking discussion on future development trends with the aim of providing valuable reference for clinical treatment

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更新日期/Last Update: 2025-12-18