[1]李强强 顾虹.中国儿童肺动脉高压诊治现状[J].心血管病学进展,2024,(1):7.[doi:10.16806/j.cnki.issn.1004-3934.2024.01.003]
 LI Qiangqiang,GU Hong.Current Status of Diagnosis and Treatment of Pulmonary Hypertension in Chinese Children[J].Advances in Cardiovascular Diseases,2024,(1):7.[doi:10.16806/j.cnki.issn.1004-3934.2024.01.003]
点击复制

中国儿童肺动脉高压诊治现状()
分享到:

《心血管病学进展》[ISSN:51-1187/R/CN:1004-3934]

卷:
期数:
2024年1期
页码:
7
栏目:
主题综述
出版日期:
2024-02-21

文章信息/Info

Title:
Current Status of Diagnosis and Treatment of Pulmonary Hypertension in Chinese Children
作者:
李强强 顾虹
(首都医科大学附属北京安贞医院小儿心脏科,北京 100029)
Author(s):
LI QiangqiangGU Hong
(Department of Pediatric Cardiology,Beijing Anzhen Hospital,Capital Medical University,Beijing 100029,China)
关键词:
肺动脉高压儿童先天性心脏病治疗
Keywords:
Pulmonary hypertensionChildrenCongenital heart diseaseTreatment
DOI:
10.16806/j.cnki.issn.1004-3934.2024.01.003
摘要:
肺动脉高压是一类具有不同的病因和发病特点、多因素致病的疾病。中国儿童肺动脉高压最常见的类型是先天性心脏病相关肺动脉高压和特发性肺动脉高压。现重点介绍这两类疾病的诊治现状,同时介绍与儿童肺动脉高压相关的其他疾病,以及分析当前存在的问题和挑战,并对未来进行展望。
Abstract:
Pulmonary hypertension is a type of disease with different causes and characteristics,and is caused by multiple factors. The most common types of pulmonary hypertension in Chinese children are congenital heart disease-associated pulmonary hypertension and idiopathic pulmonary arterial hypertension. This article focuses on the current status of diagnosis and treatment for these two types of diseases,as well as other diseases related to pediatric pulmonary hypertension. It also analyzes the current problems and challenges,and provides prospects for the future

参考文献/References:

[1].Humbert M,Kovacs G,Hoeper MM,et al. 2022 ESC/ERS Guidelines for the diagnosis and treatment of pulmonary hypertension[J]. Eur Heart J,2022,43(38):3618-3731.
[2].中华医学会呼吸病学分会肺栓塞与肺血管病学组,中国医师协会呼吸医师分会肺栓塞与肺血管病工作委员会,全国肺栓塞与肺血管病防治协作组,等. 中国肺动脉高压诊断与治疗指南(2021版) [J]. 中华医学杂志,2021,101(1):11-51.
[3].Rosenzweig EB,Abman SH,Adatia I,et al. Paediatric pulmonary arterial hypertension:updates on definition,classification,diagnostics and management[J]. Eur Respir J,2019,53(1):1801916.
[4].中华医学会小儿外科分会心脏学组,国家儿童医学中心心血管专科联盟. 儿童先天性心脏病相关性肺高压诊断与治疗指南[J]. 中华小儿外科杂志,2022,43(11):966-980.
[5].Constantine A,Dimopoulos K,Haworth SG,et al. Twenty-year experience and outcomes in a national pediatric pulmonary hypertension service[J]. Am J Respir Crit Care Med,2022,206(6):758-766.
[6].刘雪芹,杜军保,陈永红,等. 儿童肺动脉高压276例病因学分析[J]. 实用儿科临床杂志,2008,23(13):991-993.
[7].Qian Y,Quan R,Chen X,et al. Characteristics,long-term survival,and risk assessment of pediatric pulmonary arterial hypertension in China:insights from a national multicenter prospective registry[J]. Chest,2023,163(6):1531-1542.
[8].Su Z,Zhang Y,Cai X,et al. Improving long-term care and outcomes of congenital heart disease:fulfilling the promise of a healthy life[J]. Lancet Child Adolesc Health,2023,7(7):502-518.
[9].罗勤,柳志红,奚群英,等. 中国动脉型肺动脉高压患者生存现状调查[J]. 中国循环杂志,2022,37(11):1111-1115.
[10].朱治萩,孙晓琳,陈曦,等. 动脉性肺动脉高压全基因组关联研究进展[J]. 中华结核和呼吸杂志,2022,45(8):813-818.
[11].Xu Z,Zhang H,Zhang C,et al. Association between genotype,presentation,and outcome in childhood idiopathic and hereditary pulmonary arterial hypertension[J]. J Clin Med,2022,11(24):7331.
[12].Ishizuka M,Zou W,Whalen E,et al. Hereditary pulmonary arterial hypertension burden in pediatrics:a single referral center experience[J]. Front Pediatr,2023,11:1050706.
[13].Zhang HS,Liu Q,Piao CM,et al. Genotypes and phenotypes of Chinese pediatric patients with idiopathic and heritable pulmonary arterial hypertension—A single-center study[J]. Can J Cardiol,2019,35(12):1851-1856.
[14].Zhang X,Zhang C,Li Q,et al. TGF-β receptor mutations and clinical prognosis in Chinese pediatric patients with idiopathic/hereditary pulmonary arterial hypertension[J]. Pulm Circ,2022,12(2):e12076.
[15].中华医学会儿科学分会新生儿学组,中华儿科杂志编辑委员会. 早产儿支气管肺发育不良临床管理专家共识[J]. 中华儿科杂志,2020,58(5):358-365.
[16].Zani A,Chung WK,Deprest J,et al. Congenital diaphragmatic hernia[J]. Nat Rev Dis Primers,2022,8(1):37.
[17].Rosenzweig EB,Bates A,Mullen MP,et al. Cardiac catheterization and hemodynamics in a multicenter cohort of children with pulmonary hypertension[J]. Ann Am Thorac Soc,2022,19(6):1000-1012.
[18].Hansmann G,Sallmon H,Roehr CC,et al. Pulmonary hypertension in bronchopulmonary dysplasia[J]. Pediatr Res,2021,89(3):446-455.
[19].Ingram DG,Singh AV,Ehsan Z,et al. Obstructive sleep apnea and pulmonary hypertension in children[J]. Paediatr Respir Rev,2017,23:33-39.
[20].Maloney MA,Ward SLD,Su JA,et al. Prevalence of pulmonary hypertension on echocardiogram in children with severe obstructive sleep apnea[J]. J Clin Sleep Med,2022,18(6):1629-1637.
[21].Platt C,Longthorpe C,Sit J,et al. Pulmonary hypertension in juvenile-onset systemic lupus erythematosus:a case series[J]. Clin Exp Rheumatol,2023,41(9):1934-1939.
[22].邢燕,宋红梅,吴晓燕,等. 小儿结缔组织病并发的肺动脉高压临床分析[J]. 中华儿科杂志,2008,46(11):822-826.
[23].朱佳,包敏,刘小惠,等. 儿童风湿病合并肺动脉高压随访及预后分析[J] . 中华实用儿科临床杂志,2022,37(24):1873-1878.
[24].李东晓,张尧,张宏武,等. 高同型半胱氨酸血症的诊断、治疗与预防专家共识[J]. 罕少疾病杂志,2022,29(6):1-4.
[25].Gupta A,Kabra M,Gupta N,et al. Combined methylmalonic aciduria and homocystinuria presenting as pulmonary hypertension[J]. Indian J Pediatr,2021,88(12):1244-1246.
[26].Humbert M,Labrune P,Simonneau G. Severe pulmonary arterial hypertension in type 1 glycogen storage disease[J]. Eur J Pediatr,2002,161(suppl 1):S93-S96.
[27].Shindo A,Ueda K,Minatsuki S,et al. Novel AGL variants in a patient with glycogen storage disease type Ⅲb and pulmonary hypertension caused by pulmonary veno-occlusive disease:a case report[J]. Front Genet,2023,14:1148067.
[28].Yang C,Niu D,Jeng M,et al. Late-onset Pompe disease with left-sided bronchomalacia[J]. Respir Care,2015,60(2):e26-e29.
[29].Li HP,Xie WM,Huang X,et al. Pulmonary hypertension in glycogen storage disease type Ⅱ[J]. Chin Med J(Engl),2018,131(11):1375-1376.
[30].Vaksmann G,Nelken B,Deshildre A,et al. Pulmonary arterial occlusive disease following chemotherapy and bone marrow transplantation for leukaemia[J]. Eur J Pediatr,2002,161(5):247-249.
[31].郭秋霞,张美玉,王吉刚. 单倍型造血干细胞移植后血栓性微血管病致肺动脉高压一例并文献复习[J]. 中华血液学杂志,2020,41(2):164-166.
[32].陈静,顾龙君,汤静燕,等. 自身造血干细胞移植治疗儿童晚期恶性实体肿瘤[J]. 中华儿科杂志,2004,42(12):924-927.
[33].Limsuwan A,Pakakasama S,Hongeng S. Reversible course of pulmonary arterial hypertension related to bone marrow transplantation[J]. Heart Vessels,2011,26(5):557-561.
[34].Levy M,Moshous D,Szezepanski I,et al. Pulmonary hypertension after bone marrow transplantation in children[J]. Eur Respir J,2019,54(5):1900612.
[35].李强强,顾虹. 儿童肺动脉高压治疗进展[J]. 中国合理用药探索,2022,19(5):1-6.

相似文献/References:

[1]孟晓冬,单福祥,综述,等.肺动脉高压治疗进展[J].心血管病学进展,2016,(3):319.[doi:10.16806/j.cnki.issn.1004-3934.2016.03.028]
 MENG Xiaodong,SHAN Fuxiang,WANG Yanhui.Advances in Research of Pulmonary Hypertension[J].Advances in Cardiovascular Diseases,2016,(1):319.[doi:10.16806/j.cnki.issn.1004-3934.2016.03.028]
[2]张艺韬,综述,曾伟杰,等.左心疾病相关肺动脉高压流行病学[J].心血管病学进展,2016,(4):333.[doi:10.16806/j.cnki.issn.1004-3934.2016.04.002]
 ZHANG Yitao,ZENG Weijie,CHENG Kanglin.Epidemiology of Pulmonary Hypertension due to Left Heart Disease[J].Advances in Cardiovascular Diseases,2016,(1):333.[doi:10.16806/j.cnki.issn.1004-3934.2016.04.002]
[3]汪汉,刘英杰,王燕凤.长链非编码RNA与肺动脉高压[J].心血管病学进展,2019,(6):898.[doi:10.16806/j.cnki.issn.1004-3934.2019.06.015]
 WANG Han,LIU Yingjie,WANG Yanfeng.Long Non-coding RNA in Pulmonary Arterial Hypertension[J].Advances in Cardiovascular Diseases,2019,(1):898.[doi:10.16806/j.cnki.issn.1004-3934.2019.06.015]
[4]刘颖,袁美锦.儿童与青少年心脏性猝死的病因和预防[J].心血管病学进展,2019,(6):935.[doi:10.16806/j.cnki.issn.1004-3934.2019.06.024]
 LIU Ying,YUAN Meijin.Causes and Prevention of Sudden Cardiac Death in Children and Adolescents[J].Advances in Cardiovascular Diseases,2019,(1):935.[doi:10.16806/j.cnki.issn.1004-3934.2019.06.024]
[5]汪汉 邓祁 刘英杰.系统性红斑狼疮相关肺动脉高压的诊断、治疗及预后[J].心血管病学进展,2019,(8):1142.[doi:10.16806/j.cnki.issn.1004-3934.2019.08.018]
 WANG Han,DENG Qi,LIU Yingjie.Diagnosis,Treatment and Prognosis of Pulmonary Arterial Hypertension in Systemic Lupus Erythematosus[J].Advances in Cardiovascular Diseases,2019,(1):1142.[doi:10.16806/j.cnki.issn.1004-3934.2019.08.018]
[6]段宇 贾静 步睿 李涛 韦宏.急性伊洛前列素吸入对肺动脉高压患者右心室功能的影响[J].心血管病学进展,2019,(9):1319.[doi:10.16806/j.cnki.issn.1004-3934.2019.09.034]
 DUAN Yu,JIA Jing,BU Rui,et al.The Effect of Acute Iloprost Inhalation on Right Ventricular Function in Pulmonary Arterial Hypertension[J].Advances in Cardiovascular Diseases,2019,(1):1319.[doi:10.16806/j.cnki.issn.1004-3934.2019.09.034]
[7]查玉杰 何庆.肺动脉高压发生发展中的相关因子[J].心血管病学进展,2020,(2):192.[doi:10.16806/j.cnki.issn.1004-3934.2020.02.024]
 ZHA YujieHE Qing.The Relevant Factors in the Development of Pulmonary Hypertension[J].Advances in Cardiovascular Diseases,2020,(1):192.[doi:10.16806/j.cnki.issn.1004-3934.2020.02.024]
[8]朱珊英,朱国斌.肺动脉高压发病机制新进展[J].心血管病学进展,2020,(3):292.[doi:10.16806/j.cnki.issn.1004-3934.2020.03.019]
 ZHU Shanying,ZHU Guobin.Pathogenesis of Pulmonary Hypertension[J].Advances in Cardiovascular Diseases,2020,(1):292.[doi:10.16806/j.cnki.issn.1004-3934.2020.03.019]
[9]韩柯,孟祥光,赵育洁.趋化因子及其受体在肺动脉高压中的研究进展[J].心血管病学进展,2020,(3):296.[doi:10.16806/j.cnki.issn.1004-3934.2020.03.020]
 HAN Ke,MENG Xiangguang,ZHAO Yujie.Chemokines and Their Receptors in Pulmonary Arterial Hypertension[J].Advances in Cardiovascular Diseases,2020,(1):296.[doi:10.16806/j.cnki.issn.1004-3934.2020.03.020]
[10]马佳 陈肯 张宇清.儿童及青少年单纯收缩期高血压发病机制研究进展[J].心血管病学进展,2020,(4):392.[doi:10.16806/j.cnki.issn.1004-3934.2020.04.016]
 MA Jia,CHEN Ken,ZHANG Yuqing.The Pathogenesis of Isolated Systolic Hypertension in Children and Adolescents[J].Advances in Cardiovascular Diseases,2020,(1):392.[doi:10.16806/j.cnki.issn.1004-3934.2020.04.016]

更新日期/Last Update: 2024-03-06