[1]刘张弛 杨波.瞬时受体电位香草酸亚型4在心血管疾病中的研究进展[J].心血管病学进展,2023,(9):777.[doi:10.16806/j.cnki.issn.1004-3934.2023.09.000]
 LIU Zhangchi,YANG Bo?/html>.Transient Receptor Potential Vanilloid 4 in Cardiovascular Disease[J].Advances in Cardiovascular Diseases,2023,(9):777.[doi:10.16806/j.cnki.issn.1004-3934.2023.09.000]
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瞬时受体电位香草酸亚型4在心血管疾病中的研究进展()
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《心血管病学进展》[ISSN:51-1187/R/CN:1004-3934]

卷:
期数:
2023年9期
页码:
777
栏目:
综述
出版日期:
2023-09-25

文章信息/Info

Title:
Transient Receptor Potential Vanilloid 4 in Cardiovascular Disease
作者:
刘张弛 杨波
(武汉大学人民医院心内科 武汉大学心血管病研究所 心血管病湖北省重点实验室,武汉 湖北 430060)
Author(s):
LIU Zhangchi YANG Bo?/html>
?Department of Cardiology,Renmin Hospital of Wuhan University; Cardiovascular Research Institute,Wuhan University; Hubei Key Laboratory of Cardiology,Wuhan 430060,Hubei,China)
关键词:
瞬时受体电位香草酸亚型4心血管疾病动脉粥样硬化高血压心肌梗死心律失常
Keywords:
Transient receptor potential vanilloid 4 Cardiovascular diseases Atherosclerosis Hypertension Myocardial infarction Arrhythmia
DOI:
10.16806/j.cnki.issn.1004-3934.2023.09.000
摘要:
瞬时受体电位香草酸亚型4(TRPV4)是一种对渗透敏感、通过容量调节的非选择性阳离子通道。研究发现其在多种系统中均发挥重要作用。近年来越来越多的研究开始探索TRPV4在心血管疾病中的作用,包括动脉粥样硬化、高血压、心肌梗死、心律失常等。然而在不同的研究中,TRPV4的作用仍存在一定的争议。基于此,现综述近年来关于TRPV4在心血管疾病中的研究进展,以期更深入地了解该通道在心血管系统中的作用,为后续研究提供理论基础。
Abstract:
Transient receptor potential vanilloid 4 (TRPV4) is a non-selective cation channel,which is sensitive to osmosis and regulated by volume. It is found that it plays an important role in many systems. In recent years,more and more studies have begun to explore the role of TRPV4 in cardiovascular diseases,including atherosclerosis,hypertension,myocardial infarction,arrhythmia,etc. However,the role of TRPV4 remains controversial in different studies. Based on this,this article reviews the research progress of TRPV4 in cardiovascular diseases in recent years,in order to better understand the role of this channel in the cardiovascular system and provide a theoretical basis for subsequent research

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更新日期/Last Update: 2023-10-17