[1]文芳 王宏宇.阻塞性睡眠呼吸暂停与心血管相关疾病的关系研究进展[J].心血管病学进展,2021,(4):302-305.[doi:10.16806/j.cnki.issn.1004-3934.2021.04.004]
　WEN Fang,WANG Hongyu.Relationship between Obstructive Sleep Apnea and Cardiovascular Related Diseases[J].Advances in Cardiovascular Diseases,2021,(4):302-305.[doi:10.16806/j.cnki.issn.1004-3934.2021.04.004]
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阻塞性睡眠呼吸暂停与心血管相关疾病的关系研究进展()
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《心血管病学进展》[ISSN:51-1187/R/CN:1004-3934]

卷:
期数:
2021年4期
页码:
302-305
栏目:
综述
出版日期:
2021-04-25

文章信息/Info

Title:
Relationship between Obstructive Sleep Apnea and Cardiovascular Related Diseases
作者:
文芳 王宏宇
(1.北京大学首钢医院血管医学中心 北京大学医学部血管健康研究中心 北京大学医学部睡眠医学中心 分子心血管学教育部重点实验室(北京大学),北京 100144）
Author(s):
WEN Fang;  WANG Hongyu
(1.Department of Vascular Medicine,Peking University Shougang Hospital Vascular Health Research Center of Peking University Health Science Center(VHRC-PKUHSC) Sleep Medicine Center of Peking University Health Science Center Key Laboratory of Molecular Cardiovascular Sciences(Peking University), Beijing 100144,China)
关键词:
阻塞性睡眠呼吸暂停; 心血管相关疾病; 心血管健康
Keywords:
Obstructive sleep apneaCardiovascular related diseasesCardiovascular health
DOI:
10.16806/j.cnki.issn.1004-3934.2021.04.004
摘要:
阻塞性睡眠呼吸暂停（OSA）是一种慢性睡眠呼吸障碍性疾病，其间断缺氧的特征能够损伤血管内皮功能。内皮功能障碍是引起心血管疾病发生发展的早期病理过程。OSA与多种心血管相关疾病的发生密切相关，早期有效地筛查OSA及检测血管内皮功能可评估未来心血管事件的进展，显著减少OSA对心血管健康的损害。现就OSA与血管结构和功能、心血管相关疾病及心血管健康的研究进展进行综述。
Abstract:
Obstructive sleep apnea (OSA) is a chronic sleep-disordered breathing disorder,which is characterized by intermittent hypoxia that can damage vascular endothelial function. Endothelial dysfunction is an early pathological process that causes the occurrence and development of cardiovascular diseases. OSA is closely related to the occurrence of a variety of cardiovascular-related diseases. Early and effective screening of OSA and detection of vascular endothelial function can assess the progress of future cardiovascular events and significantly reduce the damage of OSA to cardiovascular health. This article reviews the research progress of OSA and vascular structure and function,cardiovascular related diseases and cardiovascular health.

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备注/Memo

备注/Memo:
基金项目：教育部科技发展中心产学研创新基金“智融兴教”基金（2018A02004）；国家重点研发计划（2017YFC0113005）；国家重点研发计划（2017YFC0113003）；2019年度临床重点项目（2019-Yuan-LC-01）；2019年度北京大学首钢医院院内科研项目（SGYYQ201912；2020年首都卫生发展科研专项（2020-2-6042） 通信作者：王宏宇，E-mail:dr.hongyuwang@foxmail.com 收稿日期：2020-09-21
更新日期/Last Update: 2021-07-01