[1]粟丽 余建群 张丽芝.改良的校正性腔内密度衰减值与冠状动脉狭窄程度及不同性质斑块在CT血管成像中的初步研究[J].心血管病学进展,2020,(8):863-867.[doi:10.16806/j.cnki.issn.1004-3934.2020.08.020]
 SU Li,YU Jianqun,ZHANG Lizhi.Primary Study on Improved Corrected Transluminal Attenuation Gradient,Degree of Coronary Artery Stenosis and Plaque with Different Properties in CT Angiography[J].Advances in Cardiovascular Diseases,2020,(8):863-867.[doi:10.16806/j.cnki.issn.1004-3934.2020.08.020]
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改良的校正性腔内密度衰减值与冠状动脉狭窄程度及不同性质斑块在CT血管成像中的初步研究()
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《心血管病学进展》[ISSN:51-1187/R/CN:1004-3934]

卷:
期数:
2020年8期
页码:
863-867
栏目:
论著
出版日期:
2020-08-25

文章信息/Info

Title:
Primary Study on Improved Corrected Transluminal Attenuation Gradient,Degree of Coronary Artery Stenosis and Plaque with Different Properties in CT Angiography
作者:
粟丽1 余建群2 张丽芝2
(1.成都市第一人民医院,四川 成都 610041;2.四川大学华西医院放射科,四川 成都 610041)
Author(s):
SU Li1YU Jianqun2ZHANG Lizhi2
(1.Department of Radiology,Chengdu First Peoples Hospital ,Chengdu 610041,Sichuan,China; 2.Department of Radiology,West China Hospital,Sichuan University,Chengdu 610041,Sichuan,China)
关键词:
冠心病冠状动脉计算机断层血管成像校正的冠状动脉腔内对比剂密度衰减值冠状动脉病变长度斑块性质
Keywords:
Coronary heart disease Coronary CT angiography Corrected transluminal attenuation gradient Coronary lesion length Plaque property
DOI:
10.16806/j.cnki.issn.1004-3934.2020.08.020
摘要:
目的 初步探讨改良的校正性腔内对比剂密度(CCO)的差值与冠状动脉狭窄程度及不同性质斑块的相关性研究。 方法 105例患者行回顾性冠状动脉 CT血管成像(CTA)检查并在15 d 内进行侵入性冠状动脉血管成像(ICA)检查或经皮冠脉介入术(PCI);经图像后处理及统计,记录冠状动脉各节段狭窄程度、斑块类别以及狭窄病变长度(L,cm)。测量冠状动脉各节段病变近侧、远侧端管腔内对比剂密度(即CT值)的变化,计算CCO差和改良CCO差(CCO差=冠状动脉狭窄近侧端腔内CT值/同层面降主动脉腔内CT值-冠状动脉狭窄远侧端腔内CT值/同层面降主动脉腔内CT值;改良CCO差=CCO差/L)。以ICA评估结果为“金标准”,先对各狭窄组中CCO差和病变长度进行相关性分析;再对各狭窄组的改良CCO差进行两两比较;在每个狭窄组中,对不同斑块性质的改良CCO差进行组间比较。结果 (1)在各狭窄组中CCO差与相应狭窄病变长度具有良好的相关性(r=0.69~0.79,P<0.001)。(2)改良CCO差随冠状动脉狭窄程度的增加而增加;狭窄1级和2级组其改良CCO差分别与余组进行比较,发现两两之间均有差异,且差异有统计学意义(P<0.001);4级组的改良CCO差明显大于3级组(P<0.001)。(3)每个狭窄程度组中不同斑块性质对应的改良CCO差值均无明显差异(P>0.05)。结论 (1)CCO差与病变长度有较好的相关性,为改良CCO差的提出提供依据;(2)随着狭窄程度的增加,改良CCO差均有增大;但改良CCO差的测量均不受斑块性质影响,它可能成为一种新的无创的评价冠心病的指标。
Abstract:
Objective To investigate the correlation between the density difference of improved corrected transluminal attenuation gradient and the degree of coronary artery stenosis and plaque with different properties.Methods 105 patients underwent retrospective coronary CT angiography, and underwent invasive coronary angiography(ICA) or percutaneous coronary intervention within 15 days.The degree of coronary artery stenosis,the type of plaque and the length of stenosis were recorded by image post-processing and statistics.The changes of contrast agent density(CT value) in the proximal and distal end of coronary artery lesions were measured,and the CCO difference and improved CCO difference were calculated (CCO difference=CT value of proximal coronary artery stenosis/CT value of descending aorta at the same level-CT value of distal end lumen of coronary artery stenosis/CT value of descending aorta at the same level; improved CCO difference=CCO difference/L).According to the results of ICA evaluation as the "gold standard",the correlation between CCO difference and lesion length in each stenosis group was analyzed,then the improved CCO difference in each stenosis group was compared,and the improved CCO difference was compared in different plaque properties in each stenosis group. Results (1)There was a good correlation between the difference of CCO and the length of corresponding stenosis in each stenosis group( r=0.69~0.79,P<0.001).(2)The improved CCO difference increased with the increase of the severity of coronary artery stenosis; the improved CCO difference of the narrow 1-stage group and the 2-stage group was compared with other groups ,and the difference was statistically significant(P<0.001).The improved CCO difference in 4-stage group was significantly larger than that in 3-stage group(P<0.001).(3)There was no significant difference in the improved CCO difference corresponding to different plaque properties in each stenosis group( P>0.05).Conclusion (1)There was a good correlation between CCO difference and lesion length ,which provided a basis for the improved CCO difference .(2)With the increase of stenosis degree,the improved CCO difference increased,but the improved CCO difference was not affected by the nature of plaques,which may become a new noninvasive index for evaluating coronary heart disease.

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备注/Memo

备注/Memo:
基金项目:国家自然科学基金(81701767,2018SZ0148)
通讯作者:张丽芝,E-mail:littche_2000@163.com
收稿日期:2019-11-14
更新日期/Last Update: 2020-11-02