[1]李甜甜 亓秉超 陈亮 李妍.以线粒体为中心的调控网络在心血管疾病中的研究进展[J].心血管病学进展,2024,(4):350.[doi:10.16806/j.cnki.issn.1004-3934.2024.04.014]
 LI Tiantian,QI Bingchao,CHEN Liang,et al.Mitochondria-Centered Regulatory Network in Cardiovascular Diseases[J].Advances in Cardiovascular Diseases,2024,(4):350.[doi:10.16806/j.cnki.issn.1004-3934.2024.04.014]
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以线粒体为中心的调控网络在心血管疾病中的研究进展()
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《心血管病学进展》[ISSN:51-1187/R/CN:1004-3934]

卷:
期数:
2024年4期
页码:
350
栏目:
综述
出版日期:
2024-04-25

文章信息/Info

Title:
Mitochondria-Centered Regulatory Network in Cardiovascular Diseases
作者:
李甜甜12 亓秉超2 陈亮1 李妍2
(1.西安医学院,陕西 西安 710021;2.空军军医大学唐都医院心血管内科,陕西 西安710038)
Author(s):
LI Tiantian12QI Bingchao2CHEN Liang1LI Yan2
(1.Xi’an Medical College,Xi’an 710021,Shaanxi,China;2.Department of Cardiology,Tangdu Hospital,Air Force Military Medical University,Xi’an 710038,Shaanxi,China)
关键词:
线粒体内质网细胞核脂滴心血管疾病
Keywords:
MitochondriaEndoplasmic reticulumNucleusLipid dropletCardiovascular disease
DOI:
10.16806/j.cnki.issn.1004-3934.2024.04.014
摘要:
线粒体是参与细胞基本功能的多功能细胞器,参与包括能量产生、活性氧生成、钙稳态、细胞存活和凋亡等过程,线粒体充当细胞中的信号枢纽,通过信号通路和直接接触位点与其他细胞器相互作用,从而在许多代谢过程中发挥核心作用。现综合线粒体与其他细胞器信号通路的传导过程及调控机制,阐述以线粒体为中心的调控网络影响细胞生命活动的机制,以及以线粒体为中心的调控网络在心血管疾病中的研究进展。
Abstract:
Mitochondria play key roles in cell regulation and signaling events,cellular responses to a variety of physiological stresses,interorganelle communication,cell proliferation,and cell death. In recent years,it has been found that mitochondria are stably coupled and interact with multiple organelles,such as the endoplasmic reticulum,nucleus,and lipid droplets,effectively promoting intracellular or intercellular signaling. This review summarizes the studies on the interaction between mitochondria and other organelles in cardiovascular diseases

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更新日期/Last Update: 2024-05-31