[1]张晓婷 郭衍楷 汤宝鹏.心房颤动与白介素家族的研究进展[J].心血管病学进展,2024,(4):340.[doi:10.16806/j.cnki.issn.1004-3934.2024.04.012]
 ZHANG Xiaoting,GUO Yankai,TANG Baopeng.Interleukin Family and Atrial Fibrillation[J].Advances in Cardiovascular Diseases,2024,(4):340.[doi:10.16806/j.cnki.issn.1004-3934.2024.04.012]
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心房颤动与白介素家族的研究进展()
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《心血管病学进展》[ISSN:51-1187/R/CN:1004-3934]

卷:
期数:
2024年4期
页码:
340
栏目:
综述
出版日期:
2024-04-25

文章信息/Info

Title:
Interleukin Family and Atrial Fibrillation
作者:
张晓婷 郭衍楷 汤宝鹏
(新疆医科大学第一附属医院心脏起搏电生理科,新疆 乌鲁木齐 830000)
Author(s):
ZHANG XiaotingGUO YankaiTANG Baopeng
(Department of Cardiac Pacing Electrophysiology,The First Affiliated Hospital of Xinjiang Medical University,Urumqi 830000,Xinjiang,China)
关键词:
心房颤动炎症因子白细胞介素心房重构电重构
Keywords:
Atrial fibrillationInflammatory factorInterleukinAtrial remodelingElectrical remodeling
DOI:
10.16806/j.cnki.issn.1004-3934.2024.04.012
摘要:
心房颤动是病理生理学机制复杂的一种心律失常。大量的临床试验及动物试验表明,心房重构及电重构的病理机制与炎症因子密切相关。炎症标志物中以白介素家族与心房颤动的发生、并发症以及射频导管消融术后复发尤为相关。这篇综述简要概述了心房颤动与白细胞介素-1β、白介素-6、白介素-8、白介素-10 和白介素-17之间的相关性以及探讨试验中发现的通过阻断白介素家族作用通路的用以预防或治疗心房颤动的药物。
Abstract:
Atrial fibrillation is a kind of arrhythmia with complex pathophysiological mechanism. A large number of clinical and animal experiments have shown that the pathological mechanism of atrial remodeling and electrical remodeling is closely related to inflammatory factors. The interleukin family of inflammatory markers is particularly associated with the occurrence, complications and recurrence of atrial fibrillation after radiofrequency catheter ablation. This review provides a brief overview of the associations between atrial fibrillation and interleukin-1β, interleukin-6, interleukin-8, interleukin-10, and interleukin-17, as well as a review of drugs found in trials to prevent or treat atrial fibrillation by blocking the interleukin-family pathway of action

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更新日期/Last Update: 2024-05-31