ZHAO Lu,SU Li.Research Progress of Atrial Fibrillation and Ion Channel Remodeling[J].Advances in Cardiovascular Diseases,2015,(5):580-584.[doi:10.3969/j.issn.1004-3934.2015.05.014]





Research Progress of Atrial Fibrillation and Ion Channel Remodeling
重庆医科大学附属第二医院心血管内科 重庆市心律失常治疗中心,重庆 400010
Department of Cardiology,The Second Affiliated Hospital of Chongqing Medical University,The Arrhythmia Therapeutic Center of Chongqing,Chongqing 400010,China
心房颤动 心房电重构 离子通道重构 离子通道药物
atrial fibrillation atrial electrical remodeling ion channel remodeling ion channel drugs
Atrial fibrillation is one of the most common clinical sustained tachyarrhythmia, which can cause serious complications like heart failure, cerebral embolism and cognitive impairment. It has a high morbidity,mortality and disability rate disease in seniors. The mechanism of atrial fibrillation is complex, and a large number of studies have shown that cardiac ion channel remodeling plays an extremely important role in the occurrence and persistence of atrial fibrillation. The drugs located in ion channel targets have been used in atrial fibrillation, which are still ineffective and cause further complications. This study explores the effective ion channel drugs that can prevent the occurrence of atrial fibrillation, delay the development of atrial fibrillation, improve the quality of life and prolong the life span in patients.


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作者简介:赵璐(1991—),在读硕士,主要从事心律失常基础与临床研究。Email: zhaoluhc@126.com 通信作者:苏立(1970—),副主任医师,博士,主要从事心律失常及心脏电生理研究。Email: sulicq@163.com
更新日期/Last Update: 2016-05-20