[1]杨伟 苗立坤 陈章荣.自噬与心肌重构研究进展[J].心血管病学进展,2022,(6):535.[doi:10.16806/j.cnki.issn.1004-3934.2022.06.014]
 YANG WeiIAO LikunCHEN Zhangrong.Autophagy and Myocardial Remodeling[J].Advances in Cardiovascular Diseases,2022,(6):535.[doi:10.16806/j.cnki.issn.1004-3934.2022.06.014]
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自噬与心肌重构研究进展()
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《心血管病学进展》[ISSN:51-1187/R/CN:1004-3934]

卷:
期数:
2022年6期
页码:
535
栏目:
综述
出版日期:
2022-06-25

文章信息/Info

Title:
Autophagy and Myocardial Remodeling
作者:
杨伟1 苗立坤1 陈章荣2
(1.漯河市中心医院,河南 漯河462000;2.550000)
Author(s):
YANG Wei1IAO Likun1CHEN Zhangrong2
(1.Luohe City Central Hospital, Luohe 462000, Henan, China; 2. The Affiliated Hospital of Guizhou Medical University, Guiyang 550000, Guizhou, China)
关键词:
自噬心肌重构心力衰竭
Keywords:
Autopagy Myocardial remodeling Heart failure
DOI:
10.16806/j.cnki.issn.1004-3934.2022.06.014
摘要:
心肌重构是心脏在一些生理或病理的刺激作用下,心肌细胞和心肌细胞外基质在细胞结构、功能、数量及遗传表型方面出现明显的变化。自噬是一种区别于细胞凋亡的程序性细胞死亡方式 ,越来越多的证据表明自噬在心肌重构过程中扮演着重要角色,然而自噬在其中的利弊仍存在争议,现从自噬在心肌重构发生发展过程中的作用、机制及治疗方面做一概述。
Abstract:
Myocardial remodeling is a significant change in the cellular structure, function, number, and genetic phenotype of myocarocytes and extracellular matrix under the action of some physiological or pathological stimuli. Autopagy is a programmed cell death mode different from apoptosis. More and more evidence shows that autophagy plays an important role in myocardial remodeling. However, the advantages and disadvantages of autophagy are still controversial. This article gives a summary of the role, mechanism and treatment of autophagy in the occurrence and development of myocardial remodeling

参考文献/References:

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更新日期/Last Update: 2022-08-05