[1]侯利莎 葛宁 赵艳莉 张蒙 谢冬梅 高浪丽 岳冀蓉 郑玉霞.老年营养风险指数对老年高血压住院患者发生谵妄的预测价值[J].心血管病学进展,2020,(7):765-769.[doi:10.16806/j.cnki.issn.1004-3934.2020.07.022]
　HOU Lisha,GE Ning,ZHAO Yanli,et al.Value of Geriatric Nutritional Risk Index in Predicting Risk of Delirium among Elderly Hypertension Patients[J].Advances in Cardiovascular Diseases,2020,(7):765-769.[doi:10.16806/j.cnki.issn.1004-3934.2020.07.022]
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老年营养风险指数对老年高血压住院患者发生谵妄的预测价值()
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《心血管病学进展》[ISSN:51-1187/R/CN:1004-3934]

卷:
期数:
2020年7期
页码:
765-769
栏目:
出版日期:
2020-07-25

文章信息/Info

Title:
Value of Geriatric Nutritional Risk Index in Predicting Risk of Delirium among Elderly Hypertension Patients
作者:
侯利莎 葛宁 赵艳莉 张蒙 谢冬梅 高浪丽 岳冀蓉 郑玉霞
(1.国家老年疾病临床医学研究中心 四川大学华西医院,四川 成都 610041;2. 四川大学华西医院老年医学中心,四川 成都 610041)
Author(s):
HOU Lisha; GE Ning; ZHAO Yanli; ZHANG Meng; XIE Dongmei; GAO Langli; YUE Jirong; ZHENG Yuxia
1.National Clinical Research Center for Geriatrics, West China Hospital, Sichuan University, Chengdu 610041 , Sichuan, China; 2. Department of Geriatrics, West China Hospital, Sichuan University, The National Center for Geriatric Clinical Research in West China Hospital, Chengdu 610041, Sichuan, China)
关键词:
老年; 高血压; 谵妄; 老年营养风险指数
Keywords:
Elderly;  Hypertension;  Delirium;  Geriatric nutritional risk index
DOI:
10.16806/j.cnki.issn.1004-3934.2020.07.022
摘要:
目的 谵妄是一种老年住院患者常见的并发症，尤其在患有高血压的老年患者中较为常见。本研究拟探讨老年营养风险指数（GNRI）在老年高血压住院患者谵妄风险评估中的预测价值。方法 选取2016年3月 —2017年1月于四川大学华西医院老年科住院且年龄≥70岁的197例高血压患者进行前瞻性研究。入院48 h 内对患者进行营养评估和谵妄相关危险因素评估，从住院当天至住院第13天每隔一天对患者进行谵妄评估，通过多因素logistic回归分析GNRI与谵妄之间的相关性，采用受试者工作特征曲线分析GNRI对老年高血压住院患者发生谵妄的预测价值。结果 最终有33例患者发生谵妄，多因素logistic回归分析结果显示GNRI是老年高血压住院患者发生谵妄的独立危险因素（OR 7.257,95% CI 1.520～34.638)，受试者工作特征曲线提示GNRI预测谵妄的曲线下面积为0.757（95% CI 0.653～0.861，P<0.001）。结论 GNRI作为一种方便快捷的指标，可初步用于老年高血压住院患者谵妄风险的评估。
Abstract:
Objective Delirium is a common complication in older inpatients, especially in elderly with hypertension, and may lead to poor prognosis. This study aimed to discuss the ability of Geriatric Nutritional Risk Index(GNRI) to predict delirium in elderly hypertension inpatients. Methods A prospective study was conducted in 197 elderly hypertension inpatients aged 70 or older at the Department of Geriatrics, West China Hospital of Sichuan University from March 2016 to January 2017. We screened nutritional status and risk factors of delirium within 48 hours after admission. Delirium screening was performed every other day from the day of admission to day 13 . Multivariable logistic regression was used to observe the association between GNRI and delirium. ROC was used to evaluate the predictive ability of GNRI in predicting the risk of delirium. Results 33 patients developed delirium in this study. Multivariable logistic regression analysis showed that GNRI was independent risk factor for delirium in elderly hypertension inpatients(OR 7.257, 95% CI 1.52 0～34.638). Based on ROC curve analyses, the AUC of GNRI was 0.757 (95% CI 0.653 ～0.861, P<0.001). Conclusion The GNRI is a rapid and convenient indicator which could be used to assess the development of delirium among elderly hypertension inpatients

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备注/Memo

备注/Memo:
基金项目：国家重点研发计划重点专项课题（2020YFC2005600），四川省科技厅（2019YFS0448, 2018SZ0252，2019YJ0033），四川省干部保健课题 (SCR 2019-102, 2019-106, 2019-109) 收稿日期：2020-05-23
更新日期/Last Update: 2020-10-10