[1]范晓飞,张清综述,刘贵京,等.乙醇性心肌病的研究进展[J].心血管病学进展,2016,(4):379-383.[doi:10.16806/j.cnki.issn.1004-3934.2016.04.014]
 FAN Xiaofei,ZHANG Qing,LIU Guijing.Research Progress of Alcoholic Cardiomyopathy[J].Advances in Cardiovascular Diseases,2016,(4):379-383.[doi:10.16806/j.cnki.issn.1004-3934.2016.04.014]
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乙醇性心肌病的研究进展()
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《心血管病学进展》[ISSN:51-1187/R/CN:1004-3934]

卷:
期数:
2016年4期
页码:
379-383
栏目:
综述
出版日期:
2016-08-15

文章信息/Info

Title:
Research Progress of Alcoholic Cardiomyopathy
作者:
范晓飞1张清2综述刘贵京3审校
1.承德医学院研究生院,河北 承德 067000; 2.重庆医科大学附属第一医院心血管内科,重庆400016; 3.河北工程大学附属医院心血管内科,河北 邯郸 056029
Author(s):
FAN Xiaofei1ZHANG Qing2LIU Guijing3
1.Chengde Medical University Graduate School, Chengde 067000,Hebei,China; 2.Department of Cardiology,The First Affiliated Hospital of Chongqing Medical University,Chongqing 400016,China; 3.Department of Cardiology, The Affiliated Hospital of Hebei Enginee
关键词:
乙醇 乙醇性心肌病 饮酒
Keywords:
Alcohol Alcoholic cardiomyopathy Drinking
分类号:
R542.2
DOI:
10.16806/j.cnki.issn.1004-3934.2016.04.014
文献标志码:
A
摘要:
乙醇性心肌病是一种与长期大量饮酒有关的非缺血性扩张型心肌病。研究表明,适量饮酒对心血管起到保护作用,而大量饮酒会导致心脏结构和功能的改变。随着社会经济的发展,人们生活水平的提高,人们饮酒的频率和饮酒量都明显增加,乙醇性心肌病发病率随之升高。其临床前期症状不明显,以心脏结构和功能改变为主,临床期主要表现为心律失常和充血性心力衰竭。乙醇性心肌病不仅增加了家庭和社会的经济负担,而且增加了患者的死亡风险。目前其发病机制尚未完全明确,并且导致乙醇性心肌病所需的乙醇量、饮酒的持续时间一直存在争议。现就乙醇性心肌病的流行病学、乙醇的剂量-时间效应、发病机制、病理改变和治疗的最新研究进展做一综述。
Abstract:
Alcoholic cardiomyopathy(ACM)is a non-ischemic dilated cardiomyopathy caused by long-term heavy drinking. Studies have shown that moderate intake of alcohol has protective effects on the cardiovascular system, while heavy consumption of alcohol may lead to changes of cardiac structure and function. With the development of the economy and improvement of people's living standards, the frequency and the amount of people drinking alcohol has greatly increased, which has caused a rising incidence of ACM. Preclinical ACM mainly presents with cardiac structural and functional changes, while the clinical stage mainly manifests arrhythmias and congestive heart failure. ACM not only increases the economic burden on family and society, but also increases the risks of death. The pathogenesis has not yet been completely explained and the consumption and duration of alcohol that caused ACM has been controversial until now. This article reviews the recent advances on epidemiology, alcohol dose-time effects, pathogenesis,pathology and treatment of ACM.

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备注/Memo

备注/Memo:
基金项目:河北省卫生厅省级重大医学科研项目(No:zd2013094) 作者简介:范晓飞(1991—),在读硕士,主要从事高血压、冠心病研究。Email:1184574792@qq.com 通信作者:刘贵京(1963—),主任医师,教授,硕士生导师,硕士,主要从事高血压、冠心病、心律失常研究。Email:13333006956@163.com
更新日期/Last Update: 2016-07-25