[1]王淼,刘静,综述,等.血管内皮钙黏蛋白参与血管内皮的完整性及其临床意义[J].心血管病学进展,2016,(4):383-387.[doi:10.16806/j.cnki.issn.1004-3934.2016.04.015]
 WANG Miao,LIU Jing,ZHAO Juan.Research Progress and Its Clinical Value of VE-Cadherin on Vascular Integrity[J].Advances in Cardiovascular Diseases,2016,(4):383-387.[doi:10.16806/j.cnki.issn.1004-3934.2016.04.015]
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血管内皮钙黏蛋白参与血管内皮的完整性及其临床意义()
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《心血管病学进展》[ISSN:51-1187/R/CN:1004-3934]

卷:
期数:
2016年4期
页码:
383-387
栏目:
综述
出版日期:
2016-08-15

文章信息/Info

Title:
Research Progress and Its Clinical Value of VE-Cadherin on Vascular Integrity
作者:
王淼刘静综述赵鹃审校
哈尔滨医科大学附属第一医院心内科,黑龙江 哈尔滨 150001
Author(s):
WANG Miao LIU JingZHAO Juan
Department of Cardiology,The First Affiliated Hospital of Harbin Medical University,Harbin 150001,Heilongjiang,China
关键词:
血管内皮钙黏蛋白 血管内皮完整性 临床意义
Keywords:
VE-cadherin Vascular integrity Clinical value
分类号:
R322.1+2; R54
DOI:
10.16806/j.cnki.issn.1004-3934.2016.04.015
文献标志码:
A
摘要:
血管内皮完整性是血管内皮发挥作用的重要基础,与多种疾病的发生、发展密切相关,如动脉粥样硬化、糖尿病、高血压、肿瘤等; 血管内皮钙黏蛋白是内皮细胞间黏附连接的一个组成成分,它在维持血管的完整性方面起着重要作用,但其作用机制相当复杂。近年随着分子生物学等的发展,人们对血管内皮钙黏蛋白与血管内皮完整性有了较深入的认识,从而对相关疾病的诊治起到重要的临床意义。
Abstract:
Vascular integrity is the basis for function of vascular endothelium,which associates with the development and advances of atherosclerosis, diabetes, hypertension and tumors. As a component of interendothelial adherens junctions, VE-cadherin has a key role in the maintenance of vascular integrity. In recent years, research has gained a deeper understanding of VE-cadherin on vascular integrity, and here we review the research progress of VE-cadherin association with vascular integrity and its clinical value.

参考文献/References:

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备注/Memo

备注/Memo:
基金项目:黑龙江省教育厅基金项目(12541544) 作者简介:王淼(1988—),在读硕士,主要从事冠心病和心律失常研究。 Email:wangmiao548@126.com 通信作者:赵鹃(1973—),副教授,副主任医师,博士,主要从事动脉粥样硬化机制研究。Email:hrbzyz@sina.com
更新日期/Last Update: 2016-07-25