[1]张世贞 唐婷 潘嘉欣 宋雨濛 刘德敏.心房颤动与动脉脉搏波传导速度的相互关系[J].心血管病学进展,2025,(11):973.[doi:10.16806/j.cnki.issn.1004-3934.2025.11.003]
 ZHANG Shizhen,TANG Ting,PAN Jiaxin,et al.Interrelationship Between Atrial Fibrillation and Arterial Pulse Wave Velocity[J].Advances in Cardiovascular Diseases,2025,(11):973.[doi:10.16806/j.cnki.issn.1004-3934.2025.11.003]
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心房颤动与动脉脉搏波传导速度的相互关系()

《心血管病学进展》[ISSN:51-1187/R/CN:1004-3934]

卷:
期数:
2025年11期
页码:
973
栏目:
综述
出版日期:
2025-11-25

文章信息/Info

Title:
Interrelationship Between Atrial Fibrillation and Arterial Pulse Wave Velocity
作者:
张世贞 唐婷 潘嘉欣 宋雨濛 刘德敏
(河北医科大学第二医院心内一科,河北 石家庄 050000 )
Author(s):
ZHANG ShizhenTANG TingPAN JiaxinSONG YumengLIU Demin
(Department of Cardiology,The Second Hospital of Hebei Medical University,Shijiazhuang 050000,Hebei,China)
关键词:
心房颤动动脉脉搏波传导速度动脉硬化
Keywords:
Atrial fibrillation Arterial pulse wave velocity Arterial stiffness
DOI:
10.16806/j.cnki.issn.1004-3934.2025.11.003
摘要:
心房颤动(AF)常与动脉脉搏波传导速度(PWV)升高并存,二者存在显著的双向交互作用。AF通过不规则心律、血流动力学紊乱及激活神经-免疫-内分泌网络,增加动脉壁应力并损害内皮功能,加速动脉硬化进展,导致PWV升高;反之,PWV升高通过增加左心室后负荷、促进左心室肥厚/舒张功能障碍及损害冠状动脉灌注,为AF的发生和维持创造电生理与结构基础。现对其相互关系及临床意义做一综述,对优化AF管理、早期识别高危人群及开发新策略具有重要参考意义。
Abstract:
Atrial fibrillation (AF) often coexists with elevated pulse wave velocity (PWV) ,and a significant bidirectional interaction exists between the two. AF increases arterial wall stress and impairs endothelial function through irregular heart rhythm,hemodynamic disturbances,and activation of the neuro-immune-endocrine network,thereby accelerating the progression of arterial stiffness and resulting in elevated PWV. Conversely,elevated PWV,by increasing left ventricular afterload,promoting left ventricular hypertrophy/diastolic dysfunction,and impairing coronary perfusion,creates an electrophysiological and structural basis for the occurrence and maintenance of AF. This review systematically explores their interrelationship and clinical significance,which is of great reference value for optimizing AF management,early identification of high-risk populations,and the development of new strategies

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更新日期/Last Update: 2026-03-06