[1]丁申申 方五旺.亲环蛋白A与动脉粥样硬化的相关研究进展[J].心血管病学进展,2025,(9):787.[doi:10.16806/j.cnki.issn.1004-3934.2025.09.005]
 DING Shenshen,FANG Wuwang.The Correlation Between Cyclophilin A and Atherosclerosis[J].Advances in Cardiovascular Diseases,2025,(9):787.[doi:10.16806/j.cnki.issn.1004-3934.2025.09.005]
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亲环蛋白A与动脉粥样硬化的相关研究进展()

《心血管病学进展》[ISSN:51-1187/R/CN:1004-3934]

卷:
期数:
2025年9期
页码:
787
栏目:
综述
出版日期:
2025-09-25

文章信息/Info

Title:
The Correlation Between Cyclophilin A and Atherosclerosis
作者:
丁申申 方五旺
(南京中医药大学第二附属医院心内科,江苏 南京 210017)
Author(s):
DING ShenshenFANG Wuwang
(Department of Cardiology,The Second Affiliated Hospital of Nanjing University of Chinese Medicine,Nanjing 210017,Jiangsu,China)
关键词:
动脉粥样硬化亲环蛋白A炎症靶细胞巨噬细胞胞葬作用脂质代谢氧化应激
Keywords:
AtherosclerosisCyclophilin AInflammationTarget cellMacrophage efferocytosisLipid metabolismOxidative stress
DOI:
10.16806/j.cnki.issn.1004-3934.2025.09.005
摘要:
动脉粥样硬化是多种心血管疾病的病理基础。现就亲环蛋白A参与动脉粥样硬化病变发生发展过程中的相关机制进行综述,包括促进炎症反应,作用于靶细胞,影响巨噬细胞胞葬作用,促进脂质代谢、氧化应激等,可为动脉粥样硬化的早期干预和寻找治疗靶点提供参考。
Abstract:
Atherosclerosis is the pathological basis of various cardiovascular diseases. This article reviews the relevant mechanisms of cyclophilin A involved in the occurrence and development of atherosclerotic lesions,including promoting inflammatory response,acting on target cells,affecting macrophage efferocytosis,and promoting lipid metabolism,oxidative stress,etc. It can provide references for early intervention and therapeutic target identification in atherosclerosis

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更新日期/Last Update: 2025-12-18