[1]周桐羽 田蜜 王中素 曾祥烨 杜晓诗 高梅.秋水仙碱在冠心病患者治疗中的应用价值[J].心血管病学进展,2025,(3):220.[doi:10.16806/j.cnki.issn.1004-3934.2024.03.007]
 ZHOU Tongyu,TIAN Mi,WANG Zhongsu,et al.Therapeutic Value of Colchicine in Treatment of Patients with Coronary Heart Disease[J].Advances in Cardiovascular Diseases,2025,(3):220.[doi:10.16806/j.cnki.issn.1004-3934.2024.03.007]
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秋水仙碱在冠心病患者治疗中的应用价值()
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《心血管病学进展》[ISSN:51-1187/R/CN:1004-3934]

卷:
期数:
2025年3期
页码:
220
栏目:
综述
出版日期:
2025-03-25

文章信息/Info

Title:
Therapeutic Value of Colchicine in Treatment of Patients with Coronary Heart Disease
作者:
周桐羽1 田蜜 1 王中素 1 曾祥烨 1 杜晓诗 2 高梅12
(1.山东第一医科大学第一附属医院 山东省千佛山医院心血管病学科 山东省医药卫生心律失常重点实验室,山东 济南 250014;2.山东中医药大学第二临床医学院,山东 济南 250014)
Author(s):
ZHOU Tongyu1 TIAN Mi1 WANG Zhongsu 1 ZENG Xiangye 1 DU Xiaoshi 2 GAO Mei12
(1.Department of Cardiology,The First Affiliated Hospital of Shandong First Medical University & Shandong Provincial Qianfoshan Hospital,Shandong Medicine and Health Key Laboratory of Cardiac Electrophysiology and Arrhythmia,Jinan 250014,Shandong,China; 2.The Second Clinical College of Shandong University of Traditional Chinese Medicine,Jinan 250014,Shandong,China)
关键词:
冠心病秋水仙碱心肌梗死炎症急性冠脉综合征
Keywords:
Coronary heart disease Colchicine Myocardial infarction Inflammation Acute coronary syndrome
DOI:
10.16806/j.cnki.issn.1004-3934.2024.03.007
摘要:
炎症是动脉粥样硬化发病机制中的一个关键过程,这一认识为预防和治疗冠心病及其并发症提供了新机会。越来越多的随机对照试验表明,使用低剂量秋水仙碱可降低冠心病患者发生缺血事件的风险,特别是反复血运重建、新发心肌梗死和卒中的风险。现总结秋水仙碱的作用机制、潜在副作用和禁忌证,以及其循证医学证据,为冠心病的治疗提供理论支持。
Abstract:
The understanding that?inflammation is integral to the pathogenesis of atherosclerosis offers new avenues for the prevention and treatment of coronary heart disease and its complications. A growing number of?randomized controlled trials have indicated that low-dose colchicine significantly reduces the incidence of ischemic events in patients with coronary heart disease,particularly the risk of repeated revascularization,emerging myocardial infarction and stroke. This review summarizes the mechanism of action ,potential side effects,contraindications and evidence-based medical evidence of colchicine,to provide theoretical?support for the treatment of coronary heart disease

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更新日期/Last Update: 2025-04-29