[1]马菲 石彦 赵健元 孙锟.孕期母体维生素水平对子代先天性心脏病影响的研究进展[J].心血管病学进展,2025,(1):46.[doi:10.16806/j.cnki.issn.1004-3934.2025.01.011]
 MA Fei,SHI Yan,ZHAO Jianyuan,et al.Influence of Maternal Vitamin Levels During Pregnancy on Offspring with Congenital Heart Disease[J].Advances in Cardiovascular Diseases,2025,(1):46.[doi:10.16806/j.cnki.issn.1004-3934.2025.01.011]
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孕期母体维生素水平对子代先天性心脏病影响的研究进展()
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《心血管病学进展》[ISSN:51-1187/R/CN:1004-3934]

卷:
期数:
2025年1期
页码:
46
栏目:
综述
出版日期:
2025-01-25

文章信息/Info

Title:
Influence of Maternal Vitamin Levels During Pregnancy on Offspring with Congenital Heart Disease
作者:
马菲12 石彦3 赵健元3 孙锟45
温州医科大学医学院,浙江 温州 325035;2.温州医科大学附属第二医院育英儿童医院儿心血管科,浙江 温州 325 038;3.上海交通大学医学院心血管发育与再生医学研究所,上海 200090;4.上海交通大学医学院,上海 200030;5.上海交通大学医学院附属新华医院儿心血管科,上海 200092)
Author(s):
MA Fei12SHI Yan3ZHAO Jianyuan3SUN Kun45
College of Medicine,Wenzhou Medical University,Wenzhou 325035,Zhejiang,China; 2. Department of Pediatric Cardiology,The Second Affiliated Hospital and Yuying Childrens Hospital,Wenzhou Medical University,Wenzhou 325038,Zhejiang,China; 3.Institute for Development and Regenerative Cardiovascular Medicine,School of Medicine,Shanghai Jiao Tong University,Shanghai 200090,China; 4.College of Medicine,Shanghai Jiao Tong University,Shanghai 200030,China; 5.Department of Pediatric Cardiology,Xinhua Hospital,School of Medicine,Shanghai Jiao Tong University,Shanghai 200092,China)
关键词:
维生素B族先天性心脏病同型半胱氨酸心血管疾病
Keywords:
Vitamins B family Congenital heart disease HomocysteineCardiovascular disease
DOI:
10.16806/j.cnki.issn.1004-3934.2025.01.011
摘要:
先天性心脏病目前有多种病因,是遗传因素、孕期母体营养状况、孕前健康以及生活方式之间相互作用的结果。其中母体孕期的维生素水平与子代患先天性心脏病密切相关,孕期补充包括维生素在内的微量营养素可降低胎儿发生先天性心脏病的风险。目前关于维生素B族可降低后代患病风险的研究较多,其主要是为体内多种反应提供甲基,在心脏的发育过程中起到重要的作用,孕期补充维生素B族可降低心脏圆锥动脉干畸形的发病风险。现就孕期母体维生素水平对子代患先天性心脏病的影响进行一个系统的综述。
Abstract:
Congenital heart disease(CHD) currently has a variety of etiologies, which are the result of the interaction between genetic factors,maternal nutritional status during pregnancy,prepregnancy health,and lifestyle. The vitamin levels during pregnancy in the mother are closely related to the occurrence of CHD in the offspring. Supplementing with micronutrients, including vitamins, during pregnancy can reduce the risk of CHD in the fetus. At present,there are many studies on how the vitamin B family can reduce the risk of disease in offspring. It mainly provides methyl groups for various reactions in the body and plays an important role in the development of the heart. Supplementing with vitamin B family during pregnancy can reduce the risk of developing conotruncal heart defects. A systematic review is conducted on the influence of maternal vitamin levels during pregnancy on the development of CHD in offspring.

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更新日期/Last Update: 2025-02-26