[1]周玲梅 张文倩 张智伟.体-肺动脉分流术在建立先天性心脏病动物模型中的应用进展[J].心血管病学进展,2021,(7):628-631.[doi:10.16806/j.cnki.issn.1004-3934.2021.07.013]
 ZHOU Lingmei,ZHANG Wenqian,ZHANG Zhiwei.Application Progress of Systemic Pulmonary Arterial Shunt in Animal Model of Congenital Heart Disease[J].Advances in Cardiovascular Diseases,2021,(7):628-631.[doi:10.16806/j.cnki.issn.1004-3934.2021.07.013]
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体-肺动脉分流术在建立先天性心脏病动物模型中的应用进展()
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《心血管病学进展》[ISSN:51-1187/R/CN:1004-3934]

卷:
期数:
2021年7期
页码:
628-631
栏目:
出版日期:
2021-07-25

文章信息/Info

Title:
Application Progress of Systemic Pulmonary Arterial Shunt in Animal Model of Congenital Heart Disease
作者:
周玲梅 张文倩 张智伟
(广东省人民医院心儿科 广东省心血管病研究所,广东 广州 510080)
Author(s):
ZHOU LingmeiZHANG WenqianZHANG Zhiwei
(Department of Pediatric CardiologyGuangdong Provincial?Peoples?HospitalGuangdong Cardiovascular InstituteGuangzhou 510080,Guangdong,China)
关键词:
先天性心脏病体-肺动脉分流动物模型肺动脉高压
Keywords:
Congenital heart diseaseSystemic pulmonary arterial shuntAnimal modelPulmonary hypertension
DOI:
10.16806/j.cnki.issn.1004-3934.2021.07.013
摘要:
先天性心脏病是导致儿童死亡的一个重要病因,为研究先天性心脏病的生理病理机制,建立稳定可靠的动物模型相当重要,建立体-肺动脉分流是模拟左向右分流型先天性心脏病的关键技术。现从外科建立分流技术的发展出发,介绍体-肺动脉分流对于建立动物模型的意义,以及以介入方式建立此分流的发展和在不同模型中的应用。
Abstract:
Congenital heart disease is an important cause of death in children. To study the physiological and pathological mechanisms of congenital heart disease,it is very important to establish a stable and reliable animal model. Systemic pulmonary arterial shunt is the key technology to simulate left-to-right shunt congenital heart disease. Based on the development of technology in surgically creating a shunt,this article introduces the significance of systemic pulmonary artery shunts for the establishment of animal model,as well as the development of intervention methods to establish this shunt and its application in different models

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更新日期/Last Update: 2021-09-10