[1]何璐 吴镜.心肺运动试验对肺动脉高压的临床意义[J].心血管病学进展,2024,(6):506.[doi:10.16806/j.cnki.issn.1004-3934.2024.06.007]
 HE Lu,WU Jing.Clinical Significance of Cardiopulmonary Exercise Test for Pulmonary Hypertention[J].Advances in Cardiovascular Diseases,2024,(6):506.[doi:10.16806/j.cnki.issn.1004-3934.2024.06.007]
点击复制

心肺运动试验对肺动脉高压的临床意义()
分享到:

《心血管病学进展》[ISSN:51-1187/R/CN:1004-3934]

卷:
期数:
2024年6期
页码:
506
栏目:
综述
出版日期:
2024-06-25

文章信息/Info

Title:
Clinical Significance of Cardiopulmonary Exercise Test for Pulmonary Hypertention
作者:
何璐 吴镜
?成都市第三人民医院老年医学科,西南交通大学附属医院,四川 成都 610031)
Author(s):
HE Lu WU Jing
(Department of Geriatric Medicine, The Affiliated Hospital of Southwest Jiaotong University, The Third People’s Hospital of Chengdu, Chengdu 610031,Sichuan,China)
关键词:
心肺运动试验肺动脉高压峰值摄氧量二氧化碳通气当量
Keywords:
Cardiopulmonary exercise testingPulmonary hypertensionpeak VO2Ventilatory equivalent for carbon dioxide
DOI:
10.16806/j.cnki.issn.1004-3934.2024.06.007
摘要:
随着科技和临床医学的发展,心肺运动试验(CPET)的临床应用价值越来越受到关注和重视。CPET通过连续动态监测人体运动时肺通气换气功能、心电图、血压、血氧饱和度等指标,并通过分析其相互关系,评价机体的整体功能。2022ESC/ERS指南提出,对可疑肺动脉高压的患者,可考虑行CPET来进一步确定肺动脉高压的可能性,并有多项研究提及峰值摄氧量和二氧化碳通气当量的预测价值。现重点讨论CPET在肺动脉高压中的应用,包括早期诊断、预后评估以及康复指导的临床意义,其中以预后评估更具临床价值。
Abstract:
With the development of science, technology and clinical medicine, the clinical application value of cardiopulmonary exercise testing(CPET) has attracted more and more attention. CPET continuously and dynamically monitors lung ventilation function, electrocardiogram, blood pressure, blood oxygen saturation and other indicators during human exercise, and evaluates the overall function of the body by analyzing their relationships. The 2022ESC/ERS guidelines suggest that CPET can be considered to further determine the likelihood of pulmonary hypertension in patients with suspected pulmonary hypertension, and a number of studies have mentioned the predictive value of peak VO2 and ventilatory equivalent for carbon dioxide. This article focuses on the application of CPET in pulmonary hypertension, including the clinical significance of early diagnosis, prognostic evaluation and rehabilitation guidance, in which prognostic evaluation is more valuable

参考文献/References:

[1] 中华医学会呼吸病学分会肺栓塞与肺血管病学组,中国医师协会呼吸医师分会肺栓塞与肺血管病工作委员会,全国肺栓塞与肺血管病防治协作组,等.中国肺动脉高压诊断与治疗指南(2021版)[J].中华医学杂志,2021,101(1):11-51.

[2] Humbert M,Kovacs G,Hoeper MM,et al. 2022 ESC/ERS Guidelines for the diagnosis and treatment of pulmonary hypertension[J]. Eur Heart J,2022,43(38):3618–3731.

[3] 谭晓越,孙兴国,何佳.肺动脉高压患者心肺运动功能特征性改变及其临床意义分析[J].中国实用内科杂志, 2013, 33(S1):65-65.

[4] Guazzi M,Arena R,Halle M,et al. 2016 focused update: clinical recommendations for cardiopulmonary exercise testing data assessment in specific patient populations[J]. Circulation,2016,133(24):e694-e711.

[5]Galiè N,Humbert M,Vachiery JL,et al. 2015 ESC/ERS Guidelines for the diagnosis and treatment of pulmonary hypertension:The Joint Task Force for the Diagnosis and Treatment of Pulmonary Hypertension of the European Society of Cardiology (ESC) and the European Respiratory Society (ERS):endorsed by:Association for European Paediatric and Congenital Cardiology (AEPC), International Society for Heart and Lung Transplantation (ISHLT)[J]. Eur Heart J,2016,37(1):67-119.

[6] Guazzi M,Arena R,Halle M,et al.2016 focused update:clinical recommendations for cardiopulmonary exercise testing data assessment in specific patient populations[J].Eur Heart J,2018,39(14):1144-1161.

[7] Correale M,Tricarico L,Ferraretti A,et al. Cardiopulmonary exercise test predicts right heart catheterization[J].Eur J Clin Invest,2017,47(12). doi: 10.1111/eci.12851.

[8] Ruopp NF, Cockrill BA. Diagnosis and treatment of pulmonary arterial hypertension a review[J].JAMA,2022,327(14):1379-1391.

[9] Held M, Grün M, Holl R,et al. Cardiopulmonary exercise testing to detect chronic thromboembolic pulmonary hypertension in patients with normal echocardiography[J]. Respiration,2014,87(5):379-387.

[10] Schwaiblmair M,Faul C,Von Scheidt W,et al. Ventilatory efficiency testing as prognostic value in patients with pulmonary hypertension[J].BMC Pulm Med,2012,12(1):23-23.

[11] Morris Z,Chin L,Chan L,et al. Ventilatory efficiency among patients with pulmonary hypertension with varying levels of adaptation to exercise training[J].Medicine & Science in Sports & Exercise,2019,51(6S):421-422.

[12] van der Plas MN,van Kan C,Blumenthal J,et al. Pulmonary vascular limitation to exercise and survival in idiopathic pulmonary fibrosis[J]. Respirology,2014,19(2):269-275.

[13] 孙行行. CPET对CHD-PAH患者疾病严重程度的评估价值[D]. 上海:同济大学,2018.

[14] 陈杨,杨国玲,郭健,等.心肺运动试验和血流动力学评估特发性肺动脉高压患者预后的作用[J].国际呼吸杂志,2017,37(10):752-758.

[15] Badagliacca R,Papa S,Valli G,et al. Echocardiography combined with cardiopulmonary exercise testing for the prediction of outcome in idiopathic pulmonary arterial hypertension[J].Chest,2016,150(6):1313-1322.

[16] Badagliacca R,Papa S,Poscia R,et al. The added value of cardiopulmonary exercise testing in the follow-up of pulmonary arterial hypertension[J].J Heart Lung Transplant,2019,38(3):306-314.

[17] Missana A,Azzolini-Jacquin M,Baudouy D,et al. Rehabilitation in pulmonary arterial hypertension:REHAB-HTP[J].Arch Cardiovasc Dis,2020,12(1):149.

[18] Schwaiblmair M,Faul C,Scheidt WV,et al. Influence of specific drug therapy on cardiopulmonary exercise testing parameters in patients with pulmonary hypertension[J]. Applied Cardiopulmonary Pathophysiology,2011,15(2):71-80.

相似文献/References:

[1]孟晓冬,单福祥,综述,等.肺动脉高压治疗进展[J].心血管病学进展,2016,(3):319.[doi:10.16806/j.cnki.issn.1004-3934.2016.03.028]
 MENG Xiaodong,SHAN Fuxiang,WANG Yanhui.Advances in Research of Pulmonary Hypertension[J].Advances in Cardiovascular Diseases,2016,(6):319.[doi:10.16806/j.cnki.issn.1004-3934.2016.03.028]
[2]张艺韬,综述,曾伟杰,等.左心疾病相关肺动脉高压流行病学[J].心血管病学进展,2016,(4):333.[doi:10.16806/j.cnki.issn.1004-3934.2016.04.002]
 ZHANG Yitao,ZENG Weijie,CHENG Kanglin.Epidemiology of Pulmonary Hypertension due to Left Heart Disease[J].Advances in Cardiovascular Diseases,2016,(6):333.[doi:10.16806/j.cnki.issn.1004-3934.2016.04.002]
[3]汪汉,刘英杰,王燕凤.长链非编码RNA与肺动脉高压[J].心血管病学进展,2019,(6):898.[doi:10.16806/j.cnki.issn.1004-3934.2019.06.015]
 WANG Han,LIU Yingjie,WANG Yanfeng.Long Non-coding RNA in Pulmonary Arterial Hypertension[J].Advances in Cardiovascular Diseases,2019,(6):898.[doi:10.16806/j.cnki.issn.1004-3934.2019.06.015]
[4]蒋昭隆,刘剑雄.心肺运动试验在心脏瓣膜病的运用现状[J].心血管病学进展,2019,(6):951.[doi:10.16806/j.cnki.issn.1004-3934.201.06.028]
 JIANG Zhaolong,LIU Jianxiong.Application of Cardiopulmonary Exercise Test in Cardiac Valvular Disease[J].Advances in Cardiovascular Diseases,2019,(6):951.[doi:10.16806/j.cnki.issn.1004-3934.201.06.028]
[5]汪汉 邓祁 刘英杰.系统性红斑狼疮相关肺动脉高压的诊断、治疗及预后[J].心血管病学进展,2019,(8):1142.[doi:10.16806/j.cnki.issn.1004-3934.2019.08.018]
 WANG Han,DENG Qi,LIU Yingjie.Diagnosis,Treatment and Prognosis of Pulmonary Arterial Hypertension in Systemic Lupus Erythematosus[J].Advances in Cardiovascular Diseases,2019,(6):1142.[doi:10.16806/j.cnki.issn.1004-3934.2019.08.018]
[6]蒋昭隆刘剑雄.心肺运动试验在冠心病运用现状[J].心血管病学进展,2019,(9):1290.[doi:10.16806/j.cnki.issn.1004-3934.2019.09.027]
 JIANG Zhaolong,LIU Jianxiong.Current Status of Cardiopulmonary Exercise Test in Coronary Heart Disease[J].Advances in Cardiovascular Diseases,2019,(6):1290.[doi:10.16806/j.cnki.issn.1004-3934.2019.09.027]
[7]段宇 贾静 步睿 李涛 韦宏.急性伊洛前列素吸入对肺动脉高压患者右心室功能的影响[J].心血管病学进展,2019,(9):1319.[doi:10.16806/j.cnki.issn.1004-3934.2019.09.034]
 DUAN Yu,JIA Jing,BU Rui,et al.The Effect of Acute Iloprost Inhalation on Right Ventricular Function in Pulmonary Arterial Hypertension[J].Advances in Cardiovascular Diseases,2019,(6):1319.[doi:10.16806/j.cnki.issn.1004-3934.2019.09.034]
[8]查玉杰 何庆.肺动脉高压发生发展中的相关因子[J].心血管病学进展,2020,(2):192.[doi:10.16806/j.cnki.issn.1004-3934.2020.02.024]
 ZHA YujieHE Qing.The Relevant Factors in the Development of Pulmonary Hypertension[J].Advances in Cardiovascular Diseases,2020,(6):192.[doi:10.16806/j.cnki.issn.1004-3934.2020.02.024]
[9]朱珊英,朱国斌.肺动脉高压发病机制新进展[J].心血管病学进展,2020,(3):292.[doi:10.16806/j.cnki.issn.1004-3934.2020.03.019]
 ZHU Shanying,ZHU Guobin.Pathogenesis of Pulmonary Hypertension[J].Advances in Cardiovascular Diseases,2020,(6):292.[doi:10.16806/j.cnki.issn.1004-3934.2020.03.019]
[10]韩柯,孟祥光,赵育洁.趋化因子及其受体在肺动脉高压中的研究进展[J].心血管病学进展,2020,(3):296.[doi:10.16806/j.cnki.issn.1004-3934.2020.03.020]
 HAN Ke,MENG Xiangguang,ZHAO Yujie.Chemokines and Their Receptors in Pulmonary Arterial Hypertension[J].Advances in Cardiovascular Diseases,2020,(6):296.[doi:10.16806/j.cnki.issn.1004-3934.2020.03.020]
[11]张毅 罗勤 赵智慧 赵青 柳志红.心肺运动试验应用于系统性硬化病相关肺动脉高压筛查的研究进展[J].心血管病学进展,2021,(7):577.[doi:10.16806/j.cnki.issn.1004-3934.2021.07.001]
 ZHANG Yi,LUO Qin,ZHAO Zhihui,et al.Cardiopulmonary Exercise Test for Screening of Systemic Sclerosis-Associated Pulmonary Hypertension[J].Advances in Cardiovascular Diseases,2021,(6):577.[doi:10.16806/j.cnki.issn.1004-3934.2021.07.001]
[12]谢佳 唐红 徐婷 边叶婷.心肺运动试验在右心疾病中的应用[J].心血管病学进展,2021,(10):873.[doi:10.16806/j.cnki.issn.1004-3934.2021.10.003]
 XIE JiaTANG HongXU TingBIAN Yeting.Application of Cardiopulmonary Exercise Test in Right Heart Disease[J].Advances in Cardiovascular Diseases,2021,(6):873.[doi:10.16806/j.cnki.issn.1004-3934.2021.10.003]

更新日期/Last Update: 2024-07-26