[1]谭运择 智琲琲 王清清 罗松 蔡军.系统性红斑狼疮肺动脉高压无创影像学研究现状与进展[J].心血管病学进展,2022,(12):1101.[doi:10.16806/j.cnki.issn.1004-3934.2022.12.010]
 TAN Yunze,ZHI Beibei,WANG Qingqing,et al.Noninvasive Imaging Study of Pulmonary Arterial Hypertension in Systemic Lupus Erythematosus[J].Advances in Cardiovascular Diseases,2022,(12):1101.[doi:10.16806/j.cnki.issn.1004-3934.2022.12.010]
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系统性红斑狼疮肺动脉高压无创影像学研究现状与进展()
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《心血管病学进展》[ISSN:51-1187/R/CN:1004-3934]

卷:
期数:
2022年12期
页码:
1101
栏目:
综述
出版日期:
2022-12-25

文章信息/Info

Title:
Noninvasive Imaging Study of Pulmonary Arterial Hypertension in Systemic Lupus Erythematosus
作者:
谭运择 智琲琲 王清清 罗松 蔡军
(南京大学医学院附属金陵医院东部战区总医院放射诊断科,江苏 南京210000)
Author(s):
TAN Yunze ZHI Beibei WANG Qingqing LUO Song CAI Jun
(Department of Diagnostic Radiology, Jinling Hospital, Medical School of Nanjing University, Nanjing 21000 0, Jiangsu, China)
关键词:
系统性红斑狼疮肺动脉高压影像学
Keywords:
Systemic lupus erythematosusPulmonary arterial hypertensionImaging
DOI:
10.16806/j.cnki.issn.1004-3934.2022.12.010
摘要:
系统性红斑狼疮(SLE)是一种以多器官系统受累、多种自身抗体阳性为主要特征的系统性自身免疫性疾病。肺动脉高压(PAH)是其严重并发症之一。SLE-PAH发病隐匿,致病因素复杂,早期诊断困难且预后较差,严重影响患者的生活质量与生存周期。无创影像学技术是SLE-PAH患者最常用检查手段,在SLE-PAH的早期诊断、治疗评估和预后预测方面有十分重要的意义。近年来无创影像学技术进展迅速,现对SLE-PAH不同致病机制的无创影像学研究进展进行综述。
Abstract:
Systemic lupus erythematosus(SLE) is a systemic autoimmune disease characterized by multiple organ system involvement and multiple positive autoantibodies.Pulmonary arterial hypertension(PAH) is one of its serious complications. The insidious onset of SLE-PAH, as well as its difficult early diagnosis and poor prognosis, has seriously affected the patients’ quality of life and life cycle. Non-invasive image technology is that most commonly used examination method for SLE-PAH patient, and is of great significance in the early diagnosis, treatment evaluation and prognosis prediction of SLE-PAH. In recent years, non-invasive imaging technology has made rapid progress. This article reviews the advances in non-invasive imaging studies on different pathogenic mechanisms of SLE-PAH

参考文献/References:


[1] Hassoun PM. Pulmonary arterial hypertension [J]. N Engl J Med,2021,385(25):2361-2376.

[2] D?rner T,Furie R. Novel paradigms in systemic lupus erythematosus[J]. Lancet,2019,393(10188):2344-2358.

[3] Zhao J,Wang Q,Liu Y,et al. Clinical characteristics and survival of pulmonary arterial hypertension associated with three major connective tissue diseases:a cohort study in China[J]. Int J Cardiol ,2017,236:432-437.

[4] Kim JS,Kim D,Joo YB,et al. Factors associated with development and mortality of pulmonary hypertension in systemic lupus erythematosus patients[J]. Lupus,2018,27(11):1769-1777.

[5] 中国肺动脉高压诊断与治疗指南(2021版)[J]. 中华医学杂志,2021,101(1):11-51.

[6] Tselios K,Urowitz MB. Cardiovascular and pulmonary manifestations of systemic lupus erythematosus[J]. Curr Rheumatol Rev,2017,13(3):206-218.

[7] Chen HA,Hsu TC,Yang SC,et al. Incidence and survival impact of pulmonary arterial hypertension among patients with systemic lupus erythematosus: a nationwide cohort study[J]. Arthritis Res Ther,2019,21(1):82.

[8] Stout KK,Daniels CJ,Aboulhosn JA,et al. 2018 AHA/ACC Guideline for the management of adults with congenital heart disease: a report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines[J]. J Am Coll Cardiol,2019,73(12):e81-e192.

[9] Collins N,Bastian B,Quiqueree L,et al. Abnormal pulmonary vascular responses in patients registered with a systemic autoimmunity database: pulmonary hpertension Assessment and Screening Evaluation using stress echocardiography (PHASE-I)[J]. Eur J Echocardiogr ,2006,7(6):439-446.

[10] Konstantinides SV,Meyer G,Becattini C,et al. 2019 ESC Guidelines for the diagnosis and management of acute pulmonary embolism developed in collaboration with the European Respiratory Society (ERS): The Task Force for the diagnosis and management of acute pulmonary embolism of the European Society of Cardiology (ESC)[J]. Eur Respir J,2019,54(3)

[11] Nakazawa T,Watanabe Y,Hori Y,et al. Lung perfused blood volume images with dual-energy computed tomography for chronic thromboembolic pulmonary hypertension: correlation to scintigraphy with single-photon emission computed tomography[J]. J Comput Assist Tomogr,2011,35(5):590-595.

[12] Shahin Y,Alabed S,Alkhanfar D,et al. Quantitative CT evaluation of small pulmonary vessels has functional and prognostic value in pulmonary hypertension[J]. Radiology,2022:210482.

[13] 孙学彪,刘敏. 心脏MR评估肺动脉高压右心室结构及预后的研究进展[J]. 中华放射学杂志,2021,55(9):993-996.

[14] Han QJ,Witschey WR,Fang-Yen CM,et al. Altered right ventricular kinetic energy work density and viscous energy dissipation in patients with pulmonary arterial hypertension: A pilot Study using 4D flow MRI[J]. PLoS One,2015,10(9):e0138365.

[15] Ray JC,Burger C,Mergo P,et al. Pulmonary arterial stiffness assessed by cardiovascular magnetic resonance imaging is a predictor of mild pulmonary arterial hypertension[J]. Int J Cardiovasc Imaging,2019,35(10):1881-1892.

[16] Luo S,Dou WQ,Schoepf UJ,et al. Cardiovascular magnetic resonance imaging in myocardial involvement of systemic lupus erythematosus[J]. Trends Cardiovasc Med,2022 Feb 10:S1050-1738(22)00025-1. doi: 10.1016/j.tcm.2022.02.002.

[17] Sch?fer M,Barker AJ,Kheyfets V,et al. Helicity and vorticity of pulmonary arterial flow in patients with pulmonary hypertension: quantitative analysis of flow formations[J]. J Am Heart Assoc ,2017,6(12):e007010.

[18] Reiter G,Reiter U,Kovacs G,et al. Blood flow vortices along the main pulmonary artery measured with MR imaging for diagnosis of pulmonary hypertension[J]. Radiology,2015,275(1):71-79.

[19] Remy-Jardin M,Ryerson CJ,Schiebler ML,et al. Imaging of pulmonary hypertension in adults: A position paper from the fleischner society[ J]. Radiology,2021,298(3):531-549.

[20] Rajaram S,Swift AJ,Condliffe R,et al. CT features of pulmonary arterial hypertension and its major subtypes:a systematic CT evaluation of 292 patients from the ASPIRE Registry[J]. Thorax,2015,70(4):382-387.

[21] Dara A,Arvanitaki A,Theodorakopoulou M,et al. Non-invasive assessment of endothelial dysfunction in Pulmonary arterial hypertension[J]. Mediterr J Rheumatol ,2021,32(1):6-14.

[22] Kagami K,Harada T,Yamaguchi K,et al. Association between lung ultrasound B-lines and exercise-induced pulmonary hypertension in patients with connective tissue disease[J]. Echocardiography,2021,38(8):1297-1306.

[23] 李梦涛,王迁,赵久良,等.中国成人系统性红斑狼疮相关肺动脉高压诊治共识[J].中华内科杂志,2015,54(1):81-86.

[24] Wang L,Xiong C,Li M,et al. Assessment of lung glucose uptake in patients with systemic lupus erythematosus pulmonary arterial hypertension: a quantitative FDG-PET imaging study[J]. Ann Nucl Med,2020,34(6):407-414.

[25] Borjas-Howard JF,Leeuw K,Rutgers A,et al. Risk of recurrent venous thromboembolism in autoimmune diseases:a systematic review of the literature[ J]. Semin Thromb Hemost,2019,45(2):141-149.

[26] Courtwright AM,El-Chemaly S,Dellaripa PF,et al. Survival and outcomes after lung transplantation for non-scleroderma connective tissue-related interstitial lung disease[J]. J Heart Lung Transplant,2017,36(7):763-769.

[27] Yang X,Wei D,Liu M,et al. Survival and outcomes after lung transplantation for connective tissue disease-associated interstitial lung diseases[J]. Clin Rheumatol,2021,40(9):3789-3795.

[28] Ovadia M,Tsifansky MD. V/Q-SPECT scintigraphy in pulmonary hypertension:predictor of mortality versus trigger for transplant,a british versus american perspective[J ]. JACC Cardiovasc Imaging,2018,11(10):1494-1498.

[29] Qian J,Wang Y,Huang C,et al. Survival and prognostic factors of systemic lupus erythematosus-associated pulmonary arterial hypertension:a PRISMA-compliant systematic review and meta-analysis[J]. Autoimmun Rev ,2016,15(3):250-257.

[30] Guo X,Lai J,Wang H,et al. Predictive value of non-invasive right ventricle to pulmonary circulation coupling in systemic lupus erythematosus patients with pulmonary arterial hypertension[J]. Eur Heart J Cardiovasc Imaging,2021,22(1):111-118.

[31] Xiong J,Yu S,Liu R,et al. The role of conjunctival microvasculation combined with echocardiography in evaluating pulmonary arterial hypertension in systemic lupus erythematosus[J]. Dis Markers,2021,2021:2135942.

[32] Li X,Zhang C,Sun X,et al. Prognostic factors of pulmonary hypertension associated with connective tissue disease: pulmonary artery size measured by chest CT[J]. Rheumatology (Oxford),2020,59(11):3221-3228.

[33] Guo X,Lai J,Wang H,et al. Predictive value of pulmonary arterial compliance in systemic lupus erythematosus patients with pulmonary arterial hypertension[J]. Hypertension,2020,76(4):1161-1168.

[34] Mielniczuk LM,Birnie D,Ziadi MC,et al. Relation between right ventricular function and increased right ventricular [18F]fluorodeoxyglucose accumulation in patients with heart failure[J]. Circ Cardiovasc Imaging,2011,4(1):59-66.

[35] Kazimierczyk R,Szumowski P,Nekolla SG,et al. Prognostic role of PET/MRI hybrid imaging in patients with pulmonary arterial hypertension[J]. Heart,2021,107(1):54-60.

[36] Baggen VJ,Leiner T,Post MC,et al. Cardiac magnetic resonance findings predicting mortality in patients with pulmonary arterial hypertension: a systematic review and meta-analysis[J]. Eur Radiol,2016,26(11):3771-3780.

[37] Argentiero A,Muscogiuri G,Rabbat MG,et al. The Applications of artificial intelligence in cardiovascular magnetic resonance-a comprehensive review[J]. J Clin Med,2022,11(10):2866.

[38] Willemink MJ,Persson M,Pourmorteza A,et al. Photon-counting CT:technical principles and clinical prospects[J]. Radiology,2018,289(2):293-312.

[39] Kwon JM,Kim KH,Medina-Inojosa J,et al. Artificial intelligence for early prediction of pulmonary hypertension using electrocardiography[J]. J Heart Lung Transplant,2020,39(8):805-814.

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更新日期/Last Update: 2023-02-03