[1]张仙玉 毛敏 左中.PET/CT对冠心病易损斑块和存活心肌的早期识别价值[J].心血管病学进展,2021,(9):816-819.[doi:10.16806/j.cnki.issn.1004-3934.2021.09.000]
 Value of PET/CT in Early Identification of Unstable Plaques and Viable Myocardium in Coronary Heart Disease.[J].Advances in Cardiovascular Diseases,2021,(9):816-819.[doi:10.16806/j.cnki.issn.1004-3934.2021.09.000]
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PET/CT对冠心病易损斑块和存活心肌的早期识别价值()
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《心血管病学进展》[ISSN:51-1187/R/CN:1004-3934]

卷:
期数:
2021年9期
页码:
816-819
栏目:
综述
出版日期:
2021-09-25

文章信息/Info

文章编号:
202101147
作者:
张仙玉12 毛敏2 左中2
(1.重庆医科大学研究生院,重庆 400010;2.重庆医科大学附属第一医院心血管内科,重庆 400010)
Author(s):
Value of PET/CT in Early Identification of Unstable Plaques and Viable Myocardium in Coronary Heart Disease
ZHANG Xianyu1,2, MAO Min2 , ZUO Zhong2 (1. Chongqing Medical University Graduate School, Chongqing 400010, China; 2. Department of Cardiology, The First Affiliated Hospital of Chongqing Medical University, Chongqing 400010, China)
关键词:
正电子发射型计算机断层显像仪冠心病不稳定斑块存活心肌
Keywords:
Positron emission tomography and computed tomographyCoronary heart diseaseUnstable plaqueViable myocardium
DOI:
10.16806/j.cnki.issn.1004-3934.2021.09.000
摘要:
作为分子影像技术的重要组成部分,正电子发射计算机体层显像仪具有其他传统成像手段无法比拟的高灵敏度和高特异性,可将冠状动脉粥样硬化易损斑块的早期病理生理改变和存活心肌的细胞状态可视化,为冠心病的早期防治进展带来全新的意义。现就正电子发射计算机体层显像仪对冠心病易损斑块和存活心肌的早期识别价值予以综合阐述。
Abstract:
As an important part of molecular imaging technology,positron emission tomography and computed tomography (PET/CT) has higher sensitivity and specificity than other traditional imaging methods. PET/CT can visualize the early pathophysiological changes of coronary atherosclerosis vulnerable plaques and the cell status of viable myocardium,and bring new significance to the progress of early prevention and treatment of coronary heart disease. This review focuses on the value of PET/CT in early identification of unstable plaques and viable myocardium in coronary heart disease

参考文献/References:

[1].McKenney-Drake ML,Moghbel MC,Paydary K,et al. 18F-NaF and 18F-FDG as molecular probes in the evaluation of atherosclerosis[J]. Eur J Nucl Med Mol Imaging,2018,45(12):2190-2200.
[2].Kloner RA. Stunned and hibernating myocardium:where are we nearly 4 decades later?[J]. J Am Heart Assoc,2020,9(3):e015502.
[3].Andrews JPM,Fayad ZA,Dweck MR. New methods to image unstable atherosclerotic plaques[J]. Atherosclerosis,2018,272:118-128.
[4].Davidson CQ,Phenix CP,Tai TC,et al. Searching for novel PET radiotracers:imaging cardiac perfusion,metabolism and inflammation[J]. Am J Nucl Med Mol Imaging,2018,8(3):200-227.
[5].Yap ML,Peter K. Molecular positron emission tomography in cardiac ischemia/reperfusion[J]. Circ Res,2019,124(6):827-829.
[6].Jamiel A,Ebid M,Ahmed AM,et al. The role of myocardial viability in contemporary cardiac practice[J]. Heart Fail Rev,2017,22(4):401-413.
[7].Koelwyn GJ,Corr EM,Erbay E,et al. Regulation of macrophage immunometabolism in atherosclerosis[J]. Nat Immunol,2018,19(6):526-537.
[8].Barrett TJ. Macrophages in atherosclerosis regression[J]. Arterioscler Thromb Vasc Biol,2020,40(1):20-33.
[9].Joseph P,Tawakol A. Imaging atherosclerosis with positron emission tomography[J]. Eur Heart J,2016,37(39):2974-2980.
[10].MacAskill MG,Newby DE,Tavares AAS. Frontiers in positron emission tomography imaging of the vulnerable atherosclerotic plaque[J].?Cardiovasc Res,2019,115(14):1952-1962.
[11].Tarkin JM,Joshi FR,Evans NR,et al. Detection of atherosclerotic inflammation by 68Ga-DOTATATE PET compared to [18F]FDG PET imaging[J]. J Am Coll Cardiol,2017,69(14):1774-1791.
[12].Irkle A,Vesey AT,Lewis DY,et al. Identifying active vascular microcalcification by (18)F-sodium fluoride positron emission tomography[J]. Nat Commun,2015,6:7495.
[13].Tzolos E,Dweck MR. 18F-Sodium Fluoride(18F-NaF) for imaging microcalcification activity in the cardiovascular system[J]. Arterioscler Thromb Vasc Biol,2020,40(7):1620-1626.
[14].Bing R,Loganath K,Adamson P,et al. Non-invasive imaging of high-risk coronary plaque:the role of computed tomography and positron emission tomography[J]. Br J Radiol,2020,93(1113):20190740.
[15].Strauss HW,Nakahara T,Narula N,et al. Vascular calcification:the evolving relationship of vascular calcification to major acute coronary events[J]. J Nucl Med,2019,60(9):1207-1212.
[16].Moss AJ,Doris MK,Andrews JPM,et al. Molecular coronary plaque imaging using18F-fluoride[J]. Circ Cardiovasc Imaging,2019,12(8):e00857.
[17].Yonetsu T,Jang IK. Advances in intravascular imaging:new insights into the vulnerable plaque from imaging studies[J]. Korean Circ J,2018, 48(1):1-15.
[18].Kavurma MM,Rayner KJ,Karunakaran D. The walking dead:macrophage inflammation and death in atherosclerosis[J]. Curr Opin Lipidol,2017,28(2):91-98.
[19].Iwatsuka R,Matsue Y,Yonetsu T,et al. Arterial inflammation measured by 18F-FDG-PET-CT to predict coronary events in older subjects[J]. Atherosclerosis,2018,268:49-54.
[20].Hetterich H,Rominger A,Walter L,et al. Natural history of atherosclerotic disease progression as assessed by 18F-FDG PET/CT[J]. Int J Cardiovasc Imaging,2016,32(1):49-59.
[21].Nakahara T,Dweck MR,Narula N. Coronary artery calcification:from mechanism to molecular imaging[J]. JACC Cardiovasc Imaging,2017,10(5):582-593.
[22].Greenland P,Blaha MJ,Budoff MJ,et al. Coronary calcium score and cardiovascular risk[J].?J Am Coll Cardiol,2018,72(4):434-447.
[23].Strauss HW,Nakahara T,Narula N,et al. Vascular calcification:the evolving relationship of vascular calcification to major acute coronary events[J]. J Nucl Med,2019,60(9):1207-1212.
[24].Wang X,Matsumura M,Mintz GS,et al. In vivo calcium detection by comparing optical coherence tomography,intravascular ultrasound,and angiography[J]. JACC Cardiovasc Imaging,2017,10(8):869-879.
[25].H?ilund-Carlsen PF,Sturek M,Alavi A,et al. Atherosclerosis imaging with 18F-sodium fluoride PET:state-of-the-art review[J]. Eur J Nucl Med Mol Imaging,2020,47(6):1538-1551.
[26].Kwiecinski J,Tzolos E,Adamson PD,et al. Coronary18F-sodium fluoride uptake predicts outcomes in patients with coronary artery disease[J].?J Am Coll Cardiol,2020,75(24):3061-3074.
[27].Blomberg BA,Thomassen A,de Jong PA,et al. Coronary fluorine-18-sodium fluoride uptake is increased in healthy adults with an unfavorable cardiovascular risk profile:results from the CAMONA study[J]. Nucl Med Commun,2017,38(11):1007-1014.
[28].Kazakauskait? E, ?aliaduonyt?-Pek?ien? D, Rumbinait? E,et al. Positron emission tomography in the diagnosis and management of coronary artery disease[J]. Medicina (Kaunas),2018,54(3) :47.
[29].Tantawy HM,Abdelhafez YG,Helal NL,et al. Variation of contrast values for myocardial perfusion imaging in single-photon emission computed tomography/computed tomography hybrid systems with different correction methods[J].?J Clin Imaging Sci,2020,10:58.
[30].Danad I,Raijmakers PG,Driessen RS,et al. Comparison of coronary CT angiography,SPECT,PET,and hybrid imaging for diagnosis of ischemic heart disease determined by fractional flow reserve[J].?JAMA Cardiol,2017,2(10):1100-1107.
[31].Lau JMC,Raptis DA,Laforest R,et al. Cardiac positron emission tomography-magnetic resonance imaging:current status and future directions[J]. J Thorac Imaging,2018,33(3):139-146.
[32].Khalaf S,Chamsi-Pasha M,Al-Mallah MH. Assessment of myocardial viability by PET[J].?Curr Opin Cardiol,2019,34(5):466-472.

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更新日期/Last Update: 2021-10-21