[1]帅壮 魏婷 唐锴 邹璐蔚 李宗宇 王玉兵 吕湛.β1和M2受体自身抗体与心房颤动[J].心血管病学进展,2021,(3):244-247.[doi:10.16806/j.cnki.issn.1004-3934.2021.03.013]
 -adrenergic and M -muscarinic Receptor Autoantibody and Atrial Fibrillation.[J].Advances in Cardiovascular Diseases,2021,(3):244-247.[doi:10.16806/j.cnki.issn.1004-3934.2021.03.013]
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β1和M2受体自身抗体与心房颤动()
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《心血管病学进展》[ISSN:51-1187/R/CN:1004-3934]

卷:
期数:
2021年3期
页码:
244-247
栏目:
出版日期:
2021-03-25

文章信息/Info

作者:
帅壮 魏婷 唐锴 邹璐蔚 李宗宇 王玉兵 吕湛
(川北医学院附属医院,四川 南充 637000)
Author(s):
1-adrenergic and M2 -muscarinic Receptor Autoantibody and Atrial Fibrillation
SHUAI Zhuang,WEI Ting,TANG Kai,ZHOU Luwei,LI Zhongyu,Wang YubingLYU Zhan ( The Affiliated Hospital of North Sichuan Medical College, Nanchong 637000,Sichuan,China)
关键词:
心房颤动自身受体抗体β1受体自身抗体M2受体自身抗体
Keywords:
Atrial fibrillationReceptor antibody1-adrenergic receptors autoantibodyM2-muscarinic receptors autoantibody
DOI:
10.16806/j.cnki.issn.1004-3934.2021.03.013
摘要:
近年来,自身免疫在心房颤动的发生和发展以及预后评估中的作用越来越受到重视,研究显示M2受体和β1受体自身抗体通过影响心脏自主神经功能,促进心房电重构和结构重构,参与了心房颤动的发生和维持。此外,M2受体和β1受体自身抗体的水平与心房颤动患者射频导管消融术后的复发风险相关,现就其在心房颤动发生中的机制、与射频导管消融术后复发风险的关系以及在心房颤动治疗中可能的前景做一概述。
Abstract:
Recently,the role of autoimmunity in the occurrence and development and the prognosis evaluation of atrial fibrillation has been getting more and more attention . Studies have shown that β1 and M2 receptor autoantibody are involved in the occurrence and maintenance of atrial fibrillation by affecting the cardiac autonomic nerve function?comand promoting the occurrence of electrical remodeling and structural remodeling. In addition,the levels of β1-adrenergic and M2 -muscarinic receptor autoantibody are associated with the risk of recurrence after radiofrequency ablation in patients with atrial fibrillation. This article reviews the mechanism of atrial fibrillation,its relationship with the risk of recurrence after radiofrequency catheter ablation,and its possible prospect in the treatment of atrial fibrillation

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更新日期/Last Update: 2021-05-27