[1]王盼盼 刘玉辉 陈椿.左房心肌纤维化基质改良的研究进展[J].心血管病学进展,2020,(11):1192-1195.[doi:10.16806/j.cnki.issn.1004-3934.2020.11.020]
 WANG Panpan,LIU Yuhui,CHEN Chun,et al.Substrate Modification Strategy Targeting Atrial Fibrosis[J].Advances in Cardiovascular Diseases,2020,(11):1192-1195.[doi:10.16806/j.cnki.issn.1004-3934.2020.11.020]
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左房心肌纤维化基质改良的研究进展()
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《心血管病学进展》[ISSN:51-1187/R/CN:1004-3934]

卷:
期数:
2020年11期
页码:
1192-1195
栏目:
综述
出版日期:
2020-11-25

文章信息/Info

Title:
Substrate Modification Strategy Targeting Atrial Fibrosis
文章编号:
202005057
作者:
王盼盼1 刘玉辉 1 陈椿 12
(1.南京医科大学研究生院,江苏 南京 210000;2.南京医科大学第一附属医院心血管内科,江苏 南京 210029)
Author(s):
WANG Panpan1 LIU Yuhui 1 CHEN Chun1 2
Nangjing Medical University Graduate School, Nanjing 210000, Jiangsu, China; 2. Department of Cardiology, The First Affiliated Hospital of Nanjing Medical University, Nanjing 210029, Jiangsu, China)
关键词:
心房颤动心房心肌纤维化基质改良低电压区
Keywords:
Atrial fibrillation Atrial fibrosis Substrate modification Low voltage zone
DOI:
10.16806/j.cnki.issn.1004-3934.2020.11.020
摘要:
多项研究已证实心房颤动与心房心肌纤维化之间的关系。大部分患者的心房纤维化有明确原因,但仍有少数患者无明确原因,称之为纤维化性心房心肌病。心脏磁共振延迟钆显像可对心房心肌纤维化进行检测、定位和定量。近来研究表明,高密度标测可明确左房基质病变,从而有效指导基质改良,提高消融获益。多项研究证实在肺静脉隔离的基础上行纤维化基质改良策略可明显提高非阵发性心房颤动的消融成功率。
Abstract:
Many studies prove the positive correlation between atrial fibrillation and atrial fibrosis. Most patients have risk factors, but atrial fibrosis is also identified in some patients without those risk factors, which is called fibrotic atrial cardiomyopathy. Delayed-enhancement magnetic resonance imaging is gaining utility for detection, localization and quantification of the fibrotic substrate. Recently, electroanatomic high density map can depict these fibrotic areas, and guide substrate modification and improve the benefits of ablation. Many studies prove that additional substrate modification strategy after circumferential pulmonary vein isolation can significantly improve the ablation success rate of non-paroxysmal atrial fibrillation

参考文献/References:

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更新日期/Last Update: 2021-02-04