[1]乐健 何胜虎.前蛋白转化酶枯草溶菌素9致动脉粥样硬化的机制研究进展[J].心血管病学进展,2019,(7):1000-1003.[doi:10.16806/j.cnki.issn.1004-3934.2019.07.009]
 YUE Jian,HE Shenghu.Advances in the mechanism of PCSK9-induced atherosclerosis[J].Advances in Cardiovascular Diseases,2019,(7):1000-1003.[doi:10.16806/j.cnki.issn.1004-3934.2019.07.009]
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前蛋白转化酶枯草溶菌素9致动脉粥样硬化的机制研究进展()
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《心血管病学进展》[ISSN:51-1187/R/CN:1004-3934]

卷:
期数:
2019年7期
页码:
1000-1003
栏目:
综述
出版日期:
2019-10-25

文章信息/Info

Title:
Advances in the mechanism of PCSK9-induced atherosclerosis
作者:
乐健12 何胜虎1
2 何胜虎1(1. 扬州大学临床医学院 江苏省苏北人民医院心内科,江苏 扬州 225001 ;2. 大连医科大学,辽宁 大连 116044 )
Author(s):
YUE Jian1 2 HE Shenghu1
(1.Clinical?Medical?College,?Yangzhou?University,Yangzhou?225001, Jiangsu, China; 2.Dalian Medical University, Dalian 116044,China)
关键词:
前蛋白转化酶枯草溶菌素9动脉粥样硬化免疫
Keywords:
PCSK9 Atherosclerosis immune
DOI:
10.16806/j.cnki.issn.1004-3934.2019.07.009
摘要:
动脉粥样硬化是一种侵入血管壁的慢性炎症性疾病,目前研究表明前蛋白转化酶枯草溶菌素9具有抗动脉粥样硬化的能力,除了常规途径,还可能存在前蛋白转化酶枯草溶菌素9抗动脉粥样硬化作用的新途径。现综述着重于研究前蛋白转化酶枯草溶菌素9如何参与动脉粥样硬化的形成,并重点描述免疫调节机制在前蛋白转化酶枯草溶菌素9抗动脉粥样硬化中的关键作用。
Abstract:
Atherosclerosis is a chronic inflammatory disease that invades the blood vessel wall. Current studies have shown that PCSK9 has anti-atherosclerotic ability, and in addition to conventional routes, there may be a new way of anti-atherosclerosis effect of PCSK9. This review focuses on how PCSK9 is involved in the formation of atherosclerosis and focuses on the key role of immune regulatory mechanisms in the anti-atherosclerosis of PCSK9

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更新日期/Last Update: 2019-12-16