[1]吴亦融 徐健.心房颤动患者心房传导速度研究进展[J].心血管病学进展,2019,(9):1212-1215.[doi:10.16806/j.cnki.issn.1004-3934.2019.09.007]
 WU Yirong,XU Jian.Atrial Conduction Velocity in Patients with Atrial Fibrillation[J].Advances in Cardiovascular Diseases,2019,(9):1212-1215.[doi:10.16806/j.cnki.issn.1004-3934.2019.09.007]
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心房颤动患者心房传导速度研究进展()
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《心血管病学进展》[ISSN:51-1187/R/CN:1004-3934]

卷:
期数:
2019年9期
页码:
1212-1215
栏目:
综述
出版日期:
2019-12-25

文章信息/Info

Title:
Atrial Conduction Velocity in Patients with Atrial Fibrillation
作者:
吴亦融1 徐健12
(1. 安徽医科大学附属安徽省立医院心血管内科,安徽 合肥 230000;2. 中国科学技术大学附属第一医院心血管内科,安徽 合肥 230000)
Author(s):
WU Yirong1 XU Jian12
(1. Department of Cardiovascular Medicine,Anhui Provincial Hospital of Anhui Medical University, Hefei 230000 ,Anhui,China; 2. Department of Cardiovascular Medicine, First Affiliated Hospital to University of Science and Technology of China, Hefei 230000 ,Anhui,China)
关键词:
心房颤动心房纤维化传导速度缓慢传导区心房重构
Keywords:
Atrial fibrillationAtrial fibrosisConduction velocitySlow conduction zoneAtrial remodeling
DOI:
10.16806/j.cnki.issn.1004-3934.2019.09.007
摘要:
心房基质变化是目前心房颤动导管消融的研究热点。其主要表现为心房传导速度变慢、传导路径复杂。心房传导的异常进一步促进心房颤动发生和维持。当前并没有针对传导异常区域的消融策略,但已经有一些研究通过传导速度异常识别导管消融靶点。心房传导速度指导心房颤动导管消融的研究有很大前景。
Abstract:
Current studies about atrial fibrillation are focusing on the atrial substrates, which are manifested as slow atrial conduction velocity and complex conduction paths. Abnormal atrial conduction further promotes the occurrence and maintenance of atrial fibrillation. Currently, there is no catheter ablation strategy for the abnormal conduction area,However,some studies have identified catheter ablation targets through conduction abnormality. The study of atrial conduction velocity has great prospect

参考文献/References:

[1].Chugh SS,Havmoeller R,Narayanan K,et al.Worldwide epidemiology of atrial fibrillation: a Global Burden of Disease 2010 Study[J].Circulation,2014,129(8):837-847.
[2].Higa S,Lo LW.Catheter ablation of paroxysmal atrial fibrillation originating from non-pulmonary vein areas[J].Arrhythm Electrophysiol Rev,2018,7(4):273-281.
[3].Zaman JA.The rotor revolution: conduction at the eye of the storm in atrial fibrillation[J].Circ Arrhythmia Electrophysiol,2014,7(6):1230-1236.
[4].Begg GA,Holden AV,Lip GY,et al.Assessment of atrial fibrosis for the rhythm control of atrial fibrillation[J].Int J?Cardiol,2016,220:155-161.
[5].King JH,Huang CL.Determinants of myocardial conduction velocity: implications for arrhythmogenesis[J].Front Physiol,2013,4:154.
[6].Kléber AG.Basic mechanisms of cardiac impulse propagation and associated arrhythmias[J].Physiolog Rev,2004,84(2):431-488.
[7].Gaspo R,Bosch RF,Talajic M.Functional mechanisms underlying tachycardia-induced sustained atrial fibrillation in a chronic dog model[J].Circulation,1997,96(11):4027-4035.
[8].Chen L,Li QY,Yang Y,et al.Inhibitory effects of tetrandrine on the Na(+) channel of human atrial fibrillation myocardium [J].Acta Pharmacol Sin,2009,30(2):166-174.
[9].Liu M,Yang KC.Cardiac sodium channel mutations:why so many phenotypes?[J].Curr Top Membr,2016,78:513-559.
[10].Dzeshka MS,Lip GY,Snezhitskiy V.Cardiac fibrosis in patients with atrial fibrillation:mechanisms and clinical implications[J].J Am Coll?Cardiol,2015,66(8):943-959.
[11].McDowell KS,Arevalo HJ,Maleckar MM.Susceptibility to arrhythmia in the infarcted heart depends on myofibroblast density[J].Biophys J,2011,101(6):1307-1315.
[12].Dhillon PS,Gray R,Kojodjojo P,et al.Relationship between gap-junctional conductance and conduction velocity in mammalian myocardium[J].Circ Arrhythmia Electrophysiol,2013,6(6):1208-1214.
[13].Nattel S.Atrial remodeling and atrial fibrillation: recent advances and translational perspectives[J].J Am Coll?Cardiol,2014,63(22):2335-2345.
[14].Wong CX,Stiles MK,John B,et al.Direction-dependent conduction in lone atrial fibrillation[J].Heart rhythm,2010,7(9):1192-1199.
[15].Grossi S,Grassi F,Galleani L,et al.Atrial conduction velocity correlates with frequency content of bipolar signal[J].Pacing Clin Electrophysiol:PACE,2016,39(8):814-821.
[16].Honarbakhsh S,Schilling RJ,Orini M,et al.Structural remodeling and conduction velocity dynamics in the human left atrium:relationship with reentrant mechanisms sustaining atrial fibrillation[J].Heart rhythm,2019,16(1):18-25.
[17].Kojodjojo P,Kanagaratnam P,Markides V,et al.Age-related changes in human left and right atrial conduction[J].J Cardiovasc Electrophysiol,2006,17(2):120-127.
[18].Kistler PM,Sanders P,Fynn SP,et al.Electrophysiologic and electroanatomic changes in the human atrium associated with age[J].J Am Coll?Cardiol,2004,44(1):109-116.
[19].Kumagai K,Akimitsu S,Kawahira K,et al.Electrophysiological properties in chronic lone atrial fibrillation[J].Circulation,1991,84(4):1662-1668.
[20].Konings KT,Kirchhof CJ,Smeets JR,et al.High-density mapping of electrically induced atrial fibrillation in humans[J].Circulation,1994,89(4):1665-1680.
[21].Zheng Y,Xia Y,Carlson J,et al.Atrial average conduction velocity in patients with and without paroxysmal atrial fibrillation[J].Clin Physiol Funct Imaging,2017,37(6):596-601.
[22].Platonov PG,Yuan S,Hertervig E,et al.Further evidence of localized posterior interatrial conduction delay in lone paroxysmal atrial fibrillation[J].Europace,2001,3(2):100-107.
[23].Xia Y,Hertervig E,Kongstad O,et al.Deterioration of interatrial conduction in patients with paroxysmal atrial fibrillation: electroanatomic mapping of the right atrium and coronary sinus[J].Heart rhythm,2004,1(5):548-553.
[24].Papageorgiou P,Monahan K,Boyle NG,et al.Site-dependent intra-atrial conduction delay Relationship to initiation of atrial fibrillation[J].Circulation,1996,94(3):384-389.
[25].MOE GK.Atrial fibrillation as a self-sustaining arrhythmia independent of focal discharge[J].Am Heart J,1959,58(1):59-70.
[26].Abildskov JA.Additions to the wavelet hypothesis of cardiac fibrillation[J].J Cardiovasc Electrophysiol,1994,5(6):553-559.
[27].Verheule S,Tuyls E,van Hunnik A,et al.Fibrillatory conduction in the atrial free walls of goats in persistent and permanent atrial fibrillation[J].Circ Arrhythmia Electrophysiol,2010,3(6):590-599.
[28].Lee G,Kumar S,Teh A,et al.Epicardial wave mapping in human long-lasting persistent atrial fibrillation: transient rotational circuits, complex wavefronts, and disorganized activity[J].Eur Heart J,2014,35(2):86-97.
[29].Cuculich PS,Wang Y,Lindsay BD,et al.Noninvasive characterization of epicardial activation in humans with diverse atrial fibrillation patterns[J].Circulation,2010,122(14):1364-1372.
[30].Allessie MA,de Groot NM,Houben RP,et al.Electropathological substrate of long-standing persistent atrial fibrillation in patients with structural heart disease: longitudinal dissociation[J].Circ Arrhythmia Electrophysiol,2010,3(6):606-615.
[31].Roberts-Thomson KC,Stevenson I,Kistler PM,et al.The role of chronic atrial stretch and atrial fibrillation on posterior left atrial wall conduction[J].Heart rhythm,2009,6(8):1109-1117.
[32].de Groot NM,Houben RP,Smeets JL,et al.Electropathological substrate of longstanding persistent atrial fibrillation in patients with structural heart disease: epicardial breakthrough[J].Circulation,2010,122(17):1674-1682.
[33].Eckstein J,Zeemering S,Linz D,et al.Transmural conduction is the predominant mechanism of breakthrough during atrial fibrillation: evidence from simultaneous endo-epicardial high-density activation mapping[J].Circ Arrhythmia Electrophysiol,2013,6(2):334-341.
[34].Oakes RS,Badger TJ,Kholmovski EG,et al.Detection and quantification of left atrial structural remodeling with delayed-enhancement magnetic resonance imaging in patients with atrial fibrillation[J].Circulation,2009,119(13):1758-1767.
[35].Miyamoto K,Tsuchiya T,Narita S,et al.Bipolar electrogram amplitudes in the left atrium are related to local conduction velocity in patients with atrial fibrillation[J].Europace,2009,11(12):1597-1605.
[36].Koller ML,Maier SK,Gelzer AR,et al.Altered dynamics of action potential restitution and alternans in humans with structural heart disease[J].Circulation,2005,112(11):1542-1548.

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更新日期/Last Update: 2020-02-06