[1]李延广,时向民,林琨,等.心房颤动血栓形成机制研究进展[J].心血管病学进展,2015,(6):691-695.[doi:10.3969/j.issn.1004-3934.2015.06.009]
 LI Yanguang,SHI Xiangmin,LIN Kun,et al.Recent Progress in Mechanisms of Thrombogenesis in Atrial Fibrillation[J].Advances in Cardiovascular Diseases,2015,(6):691-695.[doi:10.3969/j.issn.1004-3934.2015.06.009]
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心房颤动血栓形成机制研究进展()
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《心血管病学进展》[ISSN:51-1187/R/CN:1004-3934]

卷:
期数:
2015年6期
页码:
691-695
栏目:
综述
出版日期:
2016-06-20

文章信息/Info

Title:
Recent Progress in Mechanisms of Thrombogenesis in Atrial Fibrillation
作者:
李延广时向民林琨国建萍李健单兆亮王玉堂
解放军总医院心血管内科,北京 100853
Author(s):
LI Yanguang SHI Xiangmin LIN Kun GUO Jianping LI Jian SHAN Zhaoliang WANG Yutang
Department of Cardiology, Chinese PLA General Hospital, Beijing100853, China
关键词:
心房颤动 血栓形成 机制
Keywords:
atrial fibrillation thrombogenesis mechanisms
分类号:
R541.7
DOI:
10.3969/j.issn.1004-3934.2015.06.009
文献标志码:
A
摘要:
心房颤动是临床常见的心律失常,其严重的危害在于局部血栓形成后脱落,随血液循环至各处动脉导致脑卒中与栓塞。目前主要治疗措施有口服抗凝药物及植入左心耳封堵器。但所有治疗措施的采用均基于对血栓形成机制的研究,目前在血栓形成机制中的血流动力学紊乱、内皮功能异常等方面有了新的研究成果。现对近年研究进展进行综述。
Abstract:
Atrial fibrillation is the most common arrhythmia in clinic practice. Thrombosis formed in the left atrium and left atrial appendage during atrial fibrillation can shed and induce stroke or embolism. Administration of oral anticoagulation drugs and percutaneous left atrial appendage occlusion are the major measures. All these measures are based on thrombogenesis mechanisms research. Recently, developments have been made, especially in hemodynamics disturbance and abnormal endothelial function. This article reviews the progress in mechanisms of thrombogenesis in atrial fibrillation.

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备注/Memo

备注/Memo:
基金项目:军队保健专项课题(11BJZ10) 作者简介:李延广(1990—),住院医师,在读硕士,主要从事心房颤动研究。Email:liyanguangsuper@163.com 通信作者:王玉堂(1957—),主任医师,博士,主要从事心房颤动、心脏起搏与电生理研究。Email:yutang2@me.com
更新日期/Last Update: 2016-06-20