[1]施国荣 刘婷婷 田欣 祝自新 郑文荣 王宇峰 孙芳玲 王文.Eph/ephrin信号通路在缺血性心脏病中血管生成中的研究进展[J].心血管病学进展,2021,(2):158.[doi:10.16806/j.cnki.issn.1004-3934.2021.02.016]
 Shi Guorong,Liu Tingting,Tian Xin,et al.Research Progress of Eph/ephrin Signaling Pathway in Angiogenesis of Ischemic Heart Disease[J].Advances in Cardiovascular Diseases,2021,(2):158.[doi:10.16806/j.cnki.issn.1004-3934.2021.02.016]
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Eph/ephrin信号通路在缺血性心脏病中血管生成中的研究进展()
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《心血管病学进展》[ISSN:51-1187/R/CN:1004-3934]

卷:
期数:
2021年2期
页码:
158
栏目:
综述
出版日期:
2021-02-25

文章信息/Info

Title:
Research Progress of Eph/ephrin Signaling Pathway in Angiogenesis of Ischemic Heart Disease
作者:
施国荣 刘婷婷 田欣 祝自新 郑文荣 王宇峰 孙芳玲 王文
 (北京市老年病医疗研究中心,首都医科大学宣武医院实验动物室,北京 100053)
Author(s):
Shi GuorongLiu TingtingTian XinZhu ZixinZhen WenrongWang YufengSun FanglingWang Wen
 (Beijing Geriatrics Medical Research Center,Xuanwu Hospital Animal LaboratoryCapital Medical University ,Beijing 100053,China)
关键词:
缺血性心脏病Eph/ephrin信号通路血管再生
Keywords:
Ischemic heart diseaseEph/ephrin pathwayRegeneration of vascular
DOI:
10.16806/j.cnki.issn.1004-3934.2021.02.016
摘要:
缺血性心脏病主要是粥样硬化病变导致冠状动脉梗阻进而引起心肌缺血后的左心室发生一系列病变问题,在中老年人群中的发病率和死亡率逐年增高。Eph/ephrin信号对心脏发育及血管生成等过程具有重要的作用,很可能作为心脏功能调控的关键途径。现对Eph/ephrin信号通路在血管发育及再生中的作用机制的研究进展进行综述,以期为缺血性心脏病的有效治疗提供参考。
Abstract:
Ischemic heart disease is mainly caused by atherosclerotic lesions, which leads to coronary artery obstruction,and a series of pathological changes of left ventricle. The morbidity and mortality of myocardial ischemia in middle-aged population are rapidly increasing year by year. Since Eph/ephrin signaling pathway is essential for heart development and vessels formation,it might play an important role in heart function recovery. This paper reviews the research progesses of Eph/ephrin pathway in the development and regeneration of vascular,to provide an insight into the treatment of ischemic heart disease

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更新日期/Last Update: 2021-06-16