[1]于颖  关秀茹.非编码RNA作为急性心肌梗死标志物的研究进展[J].心血管病学进展,2021,(2):153.[doi:10.16806/j. cnki. issn.1004-3934.2021.02.015]
  YU Ying,GUAN Xiuru.  The Research Progress of non-coding RNAs as Biomarkers for Acute Myocardial Infraction[J].Advances in Cardiovascular Diseases,2021,(2):153.[doi:10.16806/j. cnki. issn.1004-3934.2021.02.015]
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非编码RNA作为急性心肌梗死标志物的研究进展()
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《心血管病学进展》[ISSN:51-1187/R/CN:1004-3934]

卷:
期数:
2021年2期
页码:
153
栏目:
综述
出版日期:
2021-02-25

文章信息/Info

Title:
  The Research Progress of non-coding RNAs as Biomarkers for Acute Myocardial Infraction
作者:
于颖  关秀茹
哈尔滨医科大学附属第一医院检验科,黑龙江 哈尔滨 150000
Author(s):
 YU Ying GUAN Xiuru
 (Department of Laboratory Diagnostics,the First Affiliated Hospital of Harbin Medical University,Harbin 150000, Heilongjiang,China)
关键词:
非编码RNA急性心肌梗死标志物
Keywords:
NcRNAsAcute myocardial infarctionBiomarker
DOI:
10.16806/j. cnki. issn.1004-3934.2021.02.015
摘要:
急性心肌梗死是严重威胁人类健康的疾病之一。早期准确诊断与及时治疗能显著降低急性心肌梗死病死率,改善预后。非编码RNA是转录却不编码蛋白质的RNA,已被证明可用作多种疾病的有效生物标志物,近期研究发现它也是最有前途的新型急性心肌梗死生物标志物。现总结非编码RNA作为急性心肌梗死标志物的最新发现,并侧重于这些非编码RNA的诊断价值和评估预后的潜力。
Abstract:
Acute myocardial infarction (AMI) is one of the diseases that seriously threatens human health. Early accurate diagnosis and timely treatment can significantly reduce the mortality of AMI and improve the prognosis. Non-coding RNAs (ncRNAs) are RNA that can transcribe but don’t encode protein,and have been proven to be effective biomarkers for various diseases. Recently,studies have shown that it is also the most promising new AMI biomarker. Therefore,we summarize the latest discoveries of ncRNAs as AMI biomarkers,and focus on the diagnostic value of these ncRNAs and the potential for evaluating prognosis

参考文献/References:

[1]Benjamin EJ,Muntner P,Alonso A,et al. Heart Disease and Stroke Statistics-2019 Update:A Report From the American Heart Association[J]. Circulation,2019,139(10):e56-e528.

[2]Wang L,Jin Y. Noncoding RNAs as biomarkers for acute coronary syndrome[J]. Biomed Res Int,2020,2020:3298696.

[3]Chen Y,Tao Y,Zhang L,et al. Diagnostic and prognostic value of biomarkers in acute myocardial infarction[J]. Postgrad Med J,2019,95(1122):210-216.

[4]Wang C,Jing Q. Non-coding RNAs as biomarkers for acute myocardial infarction[J]. Acta Pharmacol Sin,2018,39(7):1110-1119.

[5]Poller W,Dimmeler S,Heymans S,et al. Non-coding RNAs in cardiovascular diseases:diagnostic and therapeutic perspectives[J]. Eur Heart J,2018,39(29):2704-2716.

[6]Ojha R,Nandani R,Pandey RK,et al. Emerging role of circulating micro RNA in the diagnosis of human infectious diseases [J]. Cell Physol,2019,234(2):1030-1043.

[7]Wexler Y,Nussinovitch U. The diagnostic value of mir-133a in ST elevation and non-ST elevation myocardial infarction:a meta-analysis[J]. Cells,2020;9(4):793.

[8]Cortez-Dias N,Costa MC,Carrilho-Ferreira P,et al. Circulating miR-122-5p/miR-133b ratio is a specific early prognostic biomarker in acute myocardial infarction[J]. Circ J,2016,80(10):2183-2191.

[9]Liu X,Fan Z,Zhao T,et al. Plasma miR-1,miR-208,miR-499 as potential predictive biomarkers for acute myocardial infarction:an independent study of Han population[J]. Exp Gerontol,2015,72:230-238.

[10]Marques FZ,Vizi D,Khammy O,et al. The transcardiac gradient of cardio-microRNAs in the failing heart[J]. Eur J Heart Fail,2016,18(8):1000-1008.

[11]Wang F,Long G,Zhao C,et al. Atherosclerosis-related circulating miRNAs as novel and sensitive predictors for acute myocardial infarction[J]. PLoS One,2014,9(9):e105734.

[12]Coskunpinar E,Cakmak HA,Kalkan AK,et al. Circulating miR-221-3p as a novel marker for early prediction of acute myocardial infarction[J]. Gene,2016,591(1):90-96.

[13]Zhang R,Lan C,Pei H,et al. Expression of circulating miR-486 and miR-150 in patients with acute myocardial infarction[J]. BMC Cardiovasc Disord,2015,15:51.

[14]Dong YM,Liu XX,Wei GQ,et al. Prediction of long-term outcome after acute myocardial infarction using circulating miR-145[J]. Scand J Clin Lab Invest,2015,75(1):85-91.

[15]Liu X,Dong Y,Chen S,et al. Circulating microRNA-146a and microRNA-21 predict left ventricular remodeling after ST- elevation myocardial infarction[J]. Cardiology,2015,132(4):233-241.

[16]Lv P,Zhou MX,He J,et al. Circulating miR-208b and miR-34a are associated with left ventricular remodeling after acute myocardial infarction[J]. Int J Mol Sci,2014,15(4):5774-5788.

[17]Liu P,Qiu CG,Li BF,et al. Clinical impact of circulating miR-133,miR-1291 and miR-663b in plasma of patients with acute myocardial infarction[J]. Diagn Pathol,2014,9:89.

[18]Wang X,Dong Y,Fang T,et al. Circulating MicroRNA-423-3p Improves the Prediction of Coronary Artery Disease in a General Population-Six-Year Follow-up Results From the China-Cardiovascular Disease Study[J]. Circ J,2020,84(7):1155-1162.

[19]He Y,Zhong JF,Huang S,et al. Elevated circulating miR-126-3p expression in patients with acute myocardial infarction:its diagnostic value[J]. Int J Clin Exp Pathol,2017,10(11):11051-11056.

[20]Li L,Li S,Wu M,et al. Early diagnostic value of circulating microRNAs in patients with suspected acute myocardial infarction[J]. J Cell Physiol,2019,234(8):13649-13658.

[21]Hao Y,Yuan H,Yu H. Downregulation of miR-483-5p decreases hypoxia-induced injury in human cardiomyocytes by targeting MAPK3[J]. Cell Mol Biol Lett,2020,25:20.

[22]Devaux Y,Mueller M,Haaf P,et al. Diagnostic and prognostic value of circulating microRNAs in patients with acute chest pain[J]. J Intern Med,2015,277(2):260-271.

[23]Agiannitopoulos K,Pavlopoulou P,Tsamis K,et al. Expression of miR-208b and miR-499 in Greek Patients with Acute Myocardial Infarction[J]. In Vivo,2018,32(2):313-318.

[24]Pourrajab F,Torkian Velashani F,Khanaghaei M,et al. Comparison of miRNA signature versus conventional biomarkers before and after off-pump coronary artery bypass graft[J]. J Pharm Biomed Anal,2017,134:11-17.

[25]Shi Y,Han Y,Niu L,et al. MiR-499 inhibited hypoxia/reoxygenation induced cardiomyocytes injury by targeting SOX6[J]. Biotechnol Lett,2019,41(6-7):837-847.

[26]Li P,Li SY,Liu M,et al. Value of the expression of miR-208,miR-494,miR-499 and miR-1303 in early diagnosis of acute myocardial infarction[J]. Life Sci,2019,232:116547.

[27]Mansouri F,Seyed Mohammadzad MH. Molecular miR-19a in acute myocardial infarction:novel potential indicators of prognosis and early diagnosis[J]. Asian Pac J Cancer Prev,2020,21(4):975-982.

[28]Yi J,An Y. Circulating miR-379 as a potential novel biomarker for diagnosis of acute myocardial infarction[J]. Eur Rev Med Pharmacol Sci,2018,22(2):540-546.

[29]Vausort M,Wagner DR,Devaux Y. Long noncoding RNAs in patients with acute myocardial infarction[J]. Circ Res,2014,115(7):668-677.

[30]Gao L,Liu Y,Guo S,et al. Circulating long noncoding RNA HOTAIR is an essential mediator of acute myocardial infarction[J]. Cell Physiol Biochem,2017,44(4):1497-1508.

[31]Yan L,Zhang Y,Zhang W,et al. lncRNA-NRF is a potential biomarker of heart failure after acute myocardial infarction[J]. J Cardiovasc Transl Res,2020.

[32]Matboli M,Shafei AE,Agwa SHA,et al. Identification of novel molecular network expression in acute myocardial infarction[J]. Curr Genomics,2019,20(5):340-348.

[33]Zhuo LA,Wen YT,Wang Y,et al. LncRNA SNHG8 is identified as a key regulator of acute myocardial infarction by RNA-seq analysis[J]. Lipids Health Dis,2019,18(1):201.

[34]Salgado-Somoza A,Zhang L,Vausort M,et al. The circular RNA MICRA for risk stratification after myocardial infarction[J]. Int J Cardiol Heart Vasc,2017,17:33-36.

[35]Zhao B,Li G,Peng J,et al. CircMACF1 attenuates acute myocardial infarction through miR-500b-5p-EMP1 axis[J]. J Cardiovasc Transl Res,2020.

[36]Bai M,Pan CL,Jiang GX,et al. CircRNA 010567 improves myocardial infarction rats through inhibiting TGF-β1[J]. Eur Rev Med Pharmacol Sci,2020,24(1):369- 375.

[37]Sun LY,Zhao JC,Ge XM,et al. Circ_LAS1L regulates cardiac fibroblast activation,growth,and migration through miR-125b/SFRP5 pathway[J]. Cell Biochem Funct,2020,38(4):443-450.

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更新日期/Last Update: 2021-06-16