[1]冯泽豪 姜萌 卜军.心脏磁共振评价化疗所致心肌损伤的研究进展[J].心血管病学进展,2019,(5):667-672.[doi:10.16806/j.cnki.issn.1004-3934.2019.05.003]
 FENG Zehao,JIANG Meng,PU Jun.Cardiovascular Magnetic Resonance for Detection of Myocardial Impairments Caused by Chemotherapy[J].Advances in Cardiovascular Diseases,2019,(5):667-672.[doi:10.16806/j.cnki.issn.1004-3934.2019.05.003]
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心脏磁共振评价化疗所致心肌损伤的研究进展()
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《心血管病学进展》[ISSN:51-1187/R/CN:1004-3934]

卷:
期数:
2019年5期
页码:
667-672
栏目:
主题综述
出版日期:
2019-08-25

文章信息/Info

Title:
Cardiovascular Magnetic Resonance for Detection of Myocardial Impairments Caused by Chemotherapy
作者:
冯泽豪 姜萌 卜军
(上海交通大学医学院附属仁济医院心内科,上海 200127 )
Author(s):
FENG Zehao JIANG Meng PU Jun
(Department of Cardiology, Renji Hospital, Shanghai Jiaotong University School of Medicine, Shanghai 200127, China)
关键词:
心脏磁共振肿瘤心脏病心肌损伤
Keywords:
Cardiac magnetic resonance Cardio-oncology Myocardial impairments
DOI:
10.16806/j.cnki.issn.1004-3934.2019.05.003
摘要:
心脏磁共振是一种新型影像学诊断工具,除了可以提供更加精准的形态学评估外,还可以较为敏感地发现化疗期间心肌组织特征以及功能学的改变,作为评价肿瘤患者的心血管预后的手段。化疗早期心肌可表现为炎症水肿,及时干预可能有效逆转或减轻心肌毒性,随着化疗进程,部分心脏毒性较大的化疗药物可能导致不可逆的心脏结构及功能变化,并导致心肌细胞萎缩及间质纤维化。
Abstract:
Cardiac magnetic resonance is a new imaging tool that can provide a precise assessment of cardiac mor phology. It can also sensitively detect myocardial tissue characteristics and functional changes during and after chemotherapy, and evaluate cardiovascular outcomes in cancer patients. In the early stage of chemotherapy, inflammation and edema may occurred on myocardium. Timely intervention could effectively reverse or reduce myocardial toxicity. However, with the progress of chemotherapy, some of the drugs with more severe cardiotoxicity may cause irreversible changes in cardiac structure and function and induce myocardial cell atrophy and interstitial fibrosis.

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更新日期/Last Update: 2019-12-23