[1]王喜梅 吴永健.阻塞性睡眠呼吸暂停与急性心肌梗死关系的研究现状与进展[J].心血管病学进展,2025,(1):1.[doi:10.16806/j.cnki.issn.1004-3934.2025.01.001]
 WANG Ximei,WU Yongjian.Obstructive Sleep Apnea and Acute Myocardial Infarction[J].Advances in Cardiovascular Diseases,2025,(1):1.[doi:10.16806/j.cnki.issn.1004-3934.2025.01.001]
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阻塞性睡眠呼吸暂停与急性心肌梗死关系的研究现状与进展()
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《心血管病学进展》[ISSN:51-1187/R/CN:1004-3934]

卷:
期数:
2025年1期
页码:
1
栏目:
综述
出版日期:
2025-01-25

文章信息/Info

Title:
Obstructive Sleep Apnea and Acute Myocardial Infarction
作者:
王喜梅 吴永健
(中国医学科学院 北京协和医学院 国家心血管病中 心 阜外医院,北京 100037)
Author(s):
WANG XimeiWU Yongjian
(Fuwai Hospital,National Center for Cardiovascular Diseases,Chinese Academy of Medical Science and Peking Union Medical College,Beijing 100037,China)
关键词:
阻塞性睡眠呼吸暂停急性心肌梗死急性冠脉综合征
Keywords:
Obstructive sleep apneaAcute myocardial infarctionAcute coronary syndrome
DOI:
10.16806/j.cnki.issn.1004-3934.2025.01.001
摘要:
阻塞性睡眠呼吸暂停通过多种机制促进冠状动脉粥样硬化的发生和发展。阻塞性睡眠呼吸暂停可影响急性心肌梗死患者的梗死面积、心脏重构、心力衰竭、微循环障碍、心律失常的发生,这类患者心肌损伤相对更严重,心脏预后更差,再发心血管事件风险更高。不过也有部分研究显示阻塞性睡眠呼吸暂停对急性心肌梗死患者起到缺血预适应的保护作用。因此,阐明该类患者的临床特征具有重要意义。现就阻塞性睡眠呼吸暂停与急性心肌梗死的相关病理生理学机制、临床特点、预后及治疗策略的相关研究进展做一综述,为此类患者的临床诊治提供进一步参考。
Abstract:
Obstructive sleep apnea(OSA)promotes the development and progression of coronary atherosclerosis through multiple mechanisms. OSA can affect the infarct size,heart remodeling,heart failure,microcirculation disturbance,and arrhythmia in patients with acute myocardial infarction(AMI). These patients have more severe myocardial damage,worse cardiac prognosis,and higher risk of recurrent cardiovascular events. However,some studies have also shown that OSA has a protective effect by ischemic preconditioning in AMI patients. Therefore,elucidating the clinical features of patients with OSA complicated with AMI is of great significance. This article will review the research progress on the pathophysiological mechanism,clinical characteristics,prognosis and treatment strategies of OSA and AMI,thus providing further reference for diagnosis and treatment of such patients.

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更新日期/Last Update: 2025-02-26