[1]徐克 孙阳 汪道文.梗阻性肥厚型心肌病的介入和外科手术治疗及进展[J].心血管病学进展,2024,(2):103.[doi:10.16806/j.cnki.issn.1004-3934.2024.02.000]
 XU Ke,SUN Yang,WANG Daowen?/html>.New Perspectives on Interventional and Surgical Treatment for?bstructive Hypertrophic Cardiomyopathy[J].Advances in Cardiovascular Diseases,2024,(2):103.[doi:10.16806/j.cnki.issn.1004-3934.2024.02.000]
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梗阻性肥厚型心肌病的介入和外科手术治疗及进展()
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《心血管病学进展》[ISSN:51-1187/R/CN:1004-3934]

卷:
期数:
2024年2期
页码:
103
栏目:
约稿
出版日期:
2024-02-25

文章信息/Info

Title:
New Perspectives on Interventional and Surgical Treatment for?bstructive Hypertrophic Cardiomyopathy
作者:
徐克 孙阳 汪道文
(华中科技大学同济医学院 华中科技大学附属同济医院心内科 湖北省心血管疾病遗传与分子机制重点实验室,湖北 武汉 430030)
Author(s):
XU KeSUN YangWANG Daowen?/html>
?Division of Cardiology,Department of Internal Medicine,Tongji Hospital,Tongji Medical College,Huazhong University of Science and Technology,Hubei Key Laboratory of Genetics and Molecular Mechanisms of Cardiological Disorders,Wuhan 430030,Hubei,China)
关键词:
梗阻性肥厚型心肌病介入治疗手术治疗
Keywords:
Obstructive hypertrophic cardiomyopathyInterventional therapySurgical therapy
DOI:
10.16806/j.cnki.issn.1004-3934.2024.02.000
摘要:
肥厚型心肌病是一种最为常见的心血管遗传学疾病,主要病因是编码肌小节蛋白或肌小节相关结构蛋白的基因变异,目前肥厚型心肌病已成为青少年猝死的头号病因,其分为梗阻性肥厚型心肌病和非梗阻性心肌病,梗阻性肥厚型心肌病相对非梗阻性心肌病死亡率更高,诊治更加困难。现从梗阻性肥厚型心肌病的治疗角度出发,对以往及近期有关的治疗手段尤其是介入和手术治疗方面的进展做一综述。
Abstract:
Hypertrophic cardiomyopathy is one of the most common cardiovascular genetic diseases which is mainly caused by the variants in the genes encoding sarcomere or sarcomere related structural protein. Now ,hypertrophic cardiomyopathy has become the first cause of sudden death in adolescents. It is divided into obstructive hypertrophic cardiomyopathy and non-obstructive hypertrophic cardiomyopathy. Obstructive hypertrophic cardiomyopathy has a higher mortality rate than non-obstructive cardiomyopathy . This article reviews the past and recent advances in the treatment of hypertrophic obstructive cardiomyopathy,especially in interventional therapy and surgery

参考文献/References:

[1]Semsarian C,Ingles J,Maron MS,et al. New perspectives on the prevalence of hypertrophic cardiomyopathy[J]. J Am Coll Cardiol,2015,65(12):1249-1254.
[2]国家心血管病中心心肌病专科联盟,中国医疗保健国际交流促进会心血管病精准医学分会“中国成人肥厚型心肌病诊断与治疗指南2023”专家组. 中国成人肥厚型心肌病诊断与治疗指南2023[J]. 中国分子心脏病学杂志,2023,23(1):5115-5149.
[3]Elliott PM,Anastasakis A,Borger MA,et al. 2014 ESC Guidelines on diagnosis and management of hypertrophic cardiomyopathy:the Task Force for the Diagnosis and Management of Hypertrophic Cardiomyopathy of the European Society of Cardiology (ESC)[J]. Eur Heart J,2014,35(39):2733-2779.
[4]Ommen SR,Mital S,Burke MA,et al. 2020 AHA/ACC Guideline for the diagnosis and treatment of patients with hypertrophic cardiomyopathy:a report of the American College of Cardiology/American Heart Association Joint Committee on Clinical Practice Guidelines[J]. J Am Coll Cardiol ,2020,76(25):e159-e240.
[5]Marian AJ,Braunwald E. Hypertrophic cardiomyopathy:genetics,pathogenesis,clinical manifestations,diagnosis,and therapy[J]. Circ Res,2017,121(7):749-770.
[6]Sigwart U. Non-surgical myocardial reduction for hypertrophic obstructive cardiomyopathy[J]. Lancet,1995,346(8969):211-214.
[7]Veselka J,Jensen MK,Liebregts M,et al. Long-term clinical outcome after alcohol septal ablation for obstructive hypertrophic cardiomyopathy:results from the Euro-ASA registry[J]. Eur Heart J,2016,37(19):1517-1523.
[8]Agarwal S,Tuzcu EM,Desai MY,et al. Updated meta-analysis of septal alcohol ablation versus myectomy for hypertrophic cardiomyopathy[J]. J Am Coll Cardiol,2010,55(8):823-834.
[9]Singh K,Qutub M,Carson K,et al. A meta analysis of current status of alcohol septal ablation and surgical myectomy for obstructive hypertrophic cardiomyopathy[J]. Catheter Cardiovasc Interv,2016,88(1):107-115.
[10]Veselka J,Faber L,Liebregts M,et al. Sex-related differences in outcomes of alcohol septal ablation for hypertrophic obstructive cardiomyopathy[J]. JACC Cardiovasc Interv,2021,14(12):1390-1392.
[11]Liebregts M,Vriesendorp PA,Mahmoodi BK,et al. A systematic review and meta-analysis of long-term outcomes after septal reduction therapy in patients with hypertrophic cardiomyopathy[J]. JACC Heart Fail,2015,3(11):896-905.
[12]Kimmelstiel C,Zisa DC,Kuttab JS,et al. Guideline-based referral for septal reduction therapy in obstructive hypertrophic cardiomyopathy is associated with excellent clinical outcomes[J]. Circ Cardiovasc Interv,2019,12(7):e007673.
[13]Mateo JJS,Gimeno JR. Alcohol septal ablation in hypertrophic cardiomyopathy[J]. Glob Cardiol Sci Pract,2018,2018(3):30.
[14]Liu L,Liu B,Li J,et al. Percutaneous intramyocardial septal radiofrequency ablation of hypertrophic obstructive cardiomyopathy:a novel minimally invasive treatment for reduction of outflow tract obstruction[J]. EuroIntervention,2018,13(18):e2112-e2113.
[15]Liu L,Li J,Zuo L,et al. Percutaneous intramyocardial septal radiofrequency ablation for hypertrophic obstructive cardiomyopathy[J]. J Am Coll Cardiol,2018,72(16):1898-1909.
[16]Liu LW,Zuo L,Zhou MY,et al. [Efficacy and safety of transthoracic echocardiography-guided percutaneous intramyocardial septal radiofrequency ablation for the treatment of patients with obstructive hypertrophic cardiomyopathy][J]. Zhonghua Xin Xue Guan Bing Za Zhi,2019,47(4):284-290.
[17]Qian D,Zhou X,Liu H,et al. Clinical value of 2D speckle tracking imaging in evaluating the effect of percutaneous intramyocardial septal radiofrequency ablation in patients with hypertrophic obstructive cardiomyopathy[J]. J Clin Ultrasound,2021,49(6):554-562.
[18]Zhou M,Ta S,Hahn RT,et al. Percutaneous intramyocardial septal radiofrequency ablation in patients with drug-refractory hypertrophic obstructive cardiomyopathy[J]. JAMA Cardiol,2022,7(5):529-538.
[19]Cooper RM ,Shahzad A,Hasleton J,et al. Radiofrequency ablation of the interventricular septum to treat outflow tract gradients in hypertrophic obstructive cardiomyopathy:a novel use of CARTOSound? technology to guide ablation[J]. Europace,2016,18(1):113-120.
[20]蒋周芩,舒茂琴,柴虹,等. CARTOSound引导下射频消融治疗肥厚型梗阻性心肌病患者的临床效果[J]. 第三军医大学学报,2021,43(8):736-740.
[21]Jiang T,Huang B,Huo S,et al. Endocardial radiofrequency ablation vs. septal myectomy in patients with hypertrophic obstructive cardiomyopathy:a systematic review and meta-analysis[J]. Front Surg ,2022,9:859205.
[22]Liu Q,Qiu H,Jiang R,et al. Selective interventricular septal radiofrequency ablation in patients with hypertrophic obstructive cardiomyopathy:who can benefit?[J]. Front Cardiovasc Med ,2021,8:743044.
[23]Borisov KV. Surgery of hypertrophic obstructive cardiomyopathy in patients with severe hypertrophy ,myocardial fibrosis,and ventricular tachycardia[J]. Ann Thorac Surg,2018,106(1):30-37.
[24]Messmer BJ. Extended myectomy for hypertrophic obstructive cardiomyopathy[J]. Ann Thorac Surg,1994,58(2):575-577.
[25]Delmo Walter EM,Siniawski H,Hetzer R. Sustained improvement after combined anterior mitral valve leaflet retention plasty and septal myectomy in preventing systolic anterior motion in hypertrophic obstructive cardiomyopathy in children[J]. Eur J Cardiothorac Surg,2009,36(3):546-552.
[26]Hong JH,Schaff HV,Nishimura RA,et al. Mitral regurgitation in patients with hypertrophic obstructive cardiomyopathy:implications for concomitant valve procedures[J]. J Am Coll Cardiol ,2016,68(14):1497-1504.
[27]Thomas F,Rader F,Siegel RJ. The use of mitraclip for symptomatic patients with hypertrophic obstructive cardiomyopathy[J]. Cardiology ,2017,137(1):58-61.
[28]Long A,Mahoney P. Use of MitraClip to target obstructive SAM in severe diffuse-type hypertrophic cardiomyopathy:case report and review of literature[J]. J Invasive Cardiol,2020,32(9):E228-E232.
[29]唐亚捷,刘健,陈钊,等. 胸腔镜下经二尖瓣入路心肌切除术治疗肥厚型梗阻性心肌病的早期效果[J]. 中华胸心血管外科杂志,2020,36(8):472-477.
[30]C J AK,Marc Gillinov A,Smedira NG,et al. Robotic trans-mitral septal myectomy and papillary muscle reorientation for HOCM combined with or without mitral valve repair :technical aspects—How we do it[J]. J Card Surg,2020,35(11):3120-3124.
[31]Fang J,Liu Y,Zhu Y,et al. First-in-human transapical beating-heart?septal myectomy in patients with hypertrophic obstructive?cardiomyopathy[J]. J Am Coll Cardiol,2023,82(7):575-586.
[32]Fananapazir L,Epstein ND,Curiel RV,et al. Long-term results of dual-chamber (DDD) pacing in obstructive hypertrophic cardiomyopathy. Evidence for progressive symptomatic and hemodynamic improvement and reduction of left ventricular hypertrophy[J]. Circulation,1994,90(6):2731-2742.
[33]Ito T,Suwa M,Sakai Y,et al. Usefulness of tissue Doppler imaging for demonstrating altered septal contraction sequence during dual-chamber pacing in obstructive hypertrophic cardiomyopathy[J]. Am J Cardiol,2005,96(11):1558-1562.
[34]Gilligan DM. Dual-chamber pacing in hypertrophic cardiomyopathy[J]. Curr Cardiol Rep,2000,2(2):154-159.
[35]Jurado Román A,Montero Cabezas JM,Rubio Alonso B,et al. Sequential atrioventricular pacing in patients with hypertrophic cardiomyopathy:an 18-year experience[J]. Rev Esp Cardiol (Engl Ed) ,2016,69(4):377-383.
[36]Maron BJ,Shen WK,Link MS,et al. Efficacy of implantable cardioverter-defibrillators for the prevention of sudden death in patients with hypertrophic cardiomyopathy[J]. N Engl J Med,2000,342(6):365-373.
[37]Maron MS,Rowin EJ,Wessler BS,et al. Enhanced American College of Cardiology/American Heart Association strategy for prevention of sudden cardiac death in high-risk patients with hypertrophic cardiomyopathy[J]. JAMA Cardiol,2019,4(7):644-657.
[38]O’mahony C,Jichi F,Pavlou M,et al. A novel clinical risk prediction model for sudden cardiac death in hypertrophic cardiomyopathy (HCM risk-SCD)[J]. Eur Heart J,2014,35(30):2010-2020.

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更新日期/Last Update: 2024-03-29