[1]韩月清 吴建军 邹昕宇 张有奇 邢磊 杨帆.红细胞在急性心肌梗死相关冠状动脉微血管障碍中的研究进展[J].心血管病学进展,2023,(6):537.[doi:10.16806/j.cnki.issn.1004-3934.2023.06.013]
 HAN Yueqing,WU Jianjun,ZOU Xinyu,et al.Study of Red Blood Cells in Coronary Microvascular Dysfunction Associated with Acute Myocardial Infarction[J].Advances in Cardiovascular Diseases,2023,(6):537.[doi:10.16806/j.cnki.issn.1004-3934.2023.06.013]
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红细胞在急性心肌梗死相关冠状动脉微血管障碍中的研究进展()
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《心血管病学进展》[ISSN:51-1187/R/CN:1004-3934]

卷:
期数:
2023年6期
页码:
537
栏目:
综述
出版日期:
2023-06-25

文章信息/Info

Title:
Study of Red Blood Cells in Coronary Microvascular Dysfunction Associated with Acute Myocardial Infarction
作者:
韩月清 吴建军1 邹昕宇12 张有奇12 邢磊12 杨帆12
(1.哈尔滨医科大学附属第二医院心血管内科,黑龙江 哈尔滨,150001;2.哈尔滨医科大学附属第二医院心肌缺血教育部重点实验室,黑龙江 哈尔滨,150001)
Author(s):
HAN Yueqing1WU Jianjun1ZOU Xinyu12ZHANG Youqi12XING Lei12YANG Fan12
Department of Cardiology,The Second Affiliated Hospital of Harbin Medical University,Harbin150001,Heilongjiang,China; 2.Key Laboratory of Myocardial Ischemia,Ministry of Education,The Second Affiliated Hospital of Harbin Medical University,Harbin 150001,Heilongjiang,China)
关键词:
红细胞急性心肌梗死冠状动脉微血管障碍血栓缺血再灌注损伤
Keywords:
Red blood cellAcute myocardial infarctionCoronary microvascular dysfunctionThrombusIschemia reperfusion injury
DOI:
10.16806/j.cnki.issn.1004-3934.2023.06.013
摘要:
冠状动脉微血管功能障碍和阻塞(CMVO)存在于近半数急诊经皮冠状动脉介入治疗成功的患者中,且与不良预后相关。缺血再灌注损伤、远端栓塞和个体微循环相互作用导致CMVO发生。红细胞是人体中最丰富的血细胞,通常占血容量的35%~45%,它们不仅参与气体交换的过程,还通过调节一氧化氮代谢和释放ATP调节心血管功能,在CMVO发展中发挥重要作用。对红细胞在急性心肌梗死相关冠状动脉微血管障碍中的研究进展进行综述。
Abstract:
Coronary microvascular dysfunction and structural obstruction(CMVO) is present in nearly half of patients with successful initial percutaneous coronary intervention and is associated with a poor prognosis. Interacting mechanisms cause CMVO in humans:ischemia-reperfusion injury,distal embolization,and individual susceptibility to the microcirculation. Red blood cells are the most abundant blood cells in the body,typically accounting for 35% to 45% of blood volume,and play an important role in the development of CMVO not only by participating in the process of gas exchange,but also by regulating nitric oxide metabolism and releasing ATP to regulate cardiovascular function. This article reviews the progress of research on erythrocytes in coronary microvascular disorders associated with acute myocardial infarction

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更新日期/Last Update: 2023-07-21