[1]张丹 钟广伟 杨海燕 时拥月 秦钦 姚佳梅.左心室心肌致密化不全心肌病的研究进展[J].心血管病学进展,2023,(4):316.[doi:10.16806/j.cnki.issn.1004-3934.2022.04.007]
 ZHANG DanZHONG Guangwei,YANG Haiyan,SHI Yongyue,et al.Left Ventricular Noncompaction Cardiomyopathy[J].Advances in Cardiovascular Diseases,2023,(4):316.[doi:10.16806/j.cnki.issn.1004-3934.2022.04.007]
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左心室心肌致密化不全心肌病的研究进展()
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《心血管病学进展》[ISSN:51-1187/R/CN:1004-3934]

卷:
期数:
2023年4期
页码:
316
栏目:
综述
出版日期:
2023-04-25

文章信息/Info

Title:
Left Ventricular Noncompaction Cardiomyopathy
作者:
张丹 钟广伟 杨海燕 时拥月 秦钦 姚佳梅
(中南大学湘雅医院,湖南 长沙 410008)
Author(s):
ZHANG DanZHONG GuangweiYANG HaiyanSHI YongyueQIN QinYAO Jiamei
(Xiangya Hospital of Central South University,Changsha 410008,Hunan,China)
关键词:
左心室心肌致密化不全心肌病发病机制预后
Keywords:
Left ventricular noncompaction cardiomyopathyPathogenesisPrognosis
DOI:
10.16806/j.cnki.issn.1004-3934.2022.04.007
摘要:
左心室心肌致密化不全心肌病作为中国第一批罕见病之一,临床表现多为心功能不全、心律失常及血栓栓塞。然而,尽管左心室心肌致密化不全心肌病在30年前首次被报道,但其发病机制尚未完全阐明。现通过综述近年相关的文献,旨在阐明与左心室心肌致密化不全心肌病发病机制相关的基因的新进展,以增加对该疾病进行基因诊断的认知,为今后该疾病在临床的诊疗提供更多的循证医学依据和参考。
Abstract:
Left ventricular noncompaction cardiomyopathy is one of the first rare diseases in China. Its clinical manifestations are mostly cardiac insufficiency,arrhythmia and thromboembolism. However,although left ventricular noncompaction cardiomyopathy was first reported 30 years ago,the pathogenesis has not been fully clarified. Therefore,this article aims to clarify the new progress of molecular signal pathways and genes that may be related to the pathogenesis of left ventricular noncompaction cardiomyopathy by reviewing relevant literature in recent years,so as to increase the cognition of gene diagnosis of this disease and provide more evidence based medical evidence and reference for the future clinical diagnosis and treatment of this disease

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更新日期/Last Update: 2023-05-17