参考文献/References:
[1] Minner SA,Simone P,Chung BB,et al. Successful reversal of bradycardia and dyspnea with aminophylline after ticagrelor load[J]. J Pharm Pract, 2018,31(1):112-114.
[2] Bonaca MP,Bhatt DL,Oude Ophuis T,et al. Long-term tolerability of ticagrelor for the secondary prevention of major adverse cardiovascular events: a secondary analysis of the PEGASUS-TIMI 54 trial[J]. JAMA Cardiol, 2016,1(4):425-432.
[3] Cannon CP,Husted S,Harrington RA,et al. Safety,tolerability,and initial efficacy of AZD6140,the first reversible oral adenosine diphosphate receptor antagonist,compared with clopidogrel,in patients with non-ST-segment elevation acute coronary syndrome:primary results of the DISPERSE-2 trial[J]. J Am Coll Cardiol,2007,50(19):1844-1851.
[4] Wallentin L,Becker RC,Budaj A,et al. Ticagrelor versus clopidogrel in patients with acute coronary syndromes[J]. N Engl J Med,2009,361(11):1045-1057.
[5] Goto S,Huang CH,Park SJ,et al. Ticagrelor vs. clopidogrel in Japanese,Korean and Taiwanese patients with acute coronary syndrome—Randomized,double-blind,phaseⅢPHILO study[J]. Circ J, 2015,79(11):2452-2460.
[6] Bonaca MP,Bhatt DL,Cohen M,et al. Long-term use of ticagrelor in patients with prior myocardial infarction[J]. N Engl J Med,2015,372(19):1791-1800.
[7] Hiatt WR,Fowkes FG,Heizer G,et al. Ticagrelor versus clopidogrel in symptomatic peripheral artery disease[J]. N Engl J Med,2017,376(1):32-40.
[8] Wong K,Amarenco P,Albers GW,et al. Efficacy and safety of ticagrelor in relation to aspirin use within the week before randomization in the SOCRATES trial[J]. Stroke,2018,49(7):1678-1685.
[9] Berwanger O,Lopes RD,Moia D,et al. Ticagrelor versus clopidogrel in patients with STEMI treated with fibrinolysis:TREAT trial[J]. J Am Coll Cardiol, 2019,73(22):2819-2828.
[10] Bhatt DL,Steg PG,Mehta SR,et al. Ticagrelor in patients with diabetes and stable coronary artery disease with a history of previous percutaneous coronary intervention(THEMIS-PCI): a phase 3,placebo-controlled,randomised trial[J]. Lancet,2019,394(10204):1169-1180.
[11] Schunkert H,Boening A,von Scheidt M,et al. Randomized trial of ticagrelor vs. aspirin in patients after coronary artery bypass grafting:the TiCAB trial[J]. Eur Heart J,2019,40(29):2432-2440.
[12] Turgeon RD,Fernandes KA,Juurlink D,et al. Ticagrelor and bradycardia:a nested case-control study[J]. Pharmacoepidemiol Drug Saf,2015,24(12):1281-1285.
[13] Bonello L,Laine M,Kipson N,et al. Ticagrelor increases adenosine plasma concentration in patients with an acute coronary syndrome[J]. J Am Coll Cardiol,2014,63(9):872-877.
[14] Nylander S,Femia EA,Scavone M,et al. Ticagrelor inhibits human platelet aggregation via adenosine in addition to P2Y12 antagonism[J]. J Thromb Haemost, 2013,11(10):1867-1876.
[15] van Giezen JJ,Sidaway J,Glaves P,et al. Ticagrelor inhibits adenosine uptake in vitro and enhances adenosine-mediated hyperemia responses in a canine model[J]. J Cardiovasc Pharmacol Ther,2012,17(2):164-172.
[16] Wittfeldt A,Emanuelsson H,Brandrup-Wognsen G,et al. Ticagrelor enhances adenosine-induced coronary vasodilatory responses in humans[J]. J Am Coll Cardiol,2013,61(7):723-727.
[17] Scirica BM,Cannon CP,Emanuelsson H,et al. The incidence of bradyarrhythmias and clinical bradyarrhythmic events in patients with acute coronary syndromes treated with ticagrelor or clopidogrel in the PLATO(Platelet Inhibition and Patient Outcomes) trial:results of the continuous electrocardiographic assessment substudy[J]. J Am Coll Cardiol,2011,57(19):1908-1916.
[18] Pujade I,Perino J,Mathieu C,et al. Risk of bradyarrhythmia related to ticagrelor:a systematic review and meta-analysis[J]. Pharmacol Res,2020,160:105089.
[19] Nicol M,Deblaise J,Choussat R,et al. Side effects of ticagrelor:sinus node dysfunction with ventricular pause[J]. Int J Cardiol,2015,191:56-57.
[20] Baker NC,Nadour W,Friehling M. Clinically significant ticagrelor induced conduction abnormalities following percutaneous coronary intervention[J]. Int J Cardiol,2016,214:21-22.
[21] 杨林承,汪羚利,聂丹,等. 替格瑞洛致房室传导阻滞一例并文献复习[J].中国心血管杂志,2019,24(6):559-561.
[22] Movahed MR. Diabetes as a risk factor for cardiac conduction defects:a review[J]. Diabetes Obes Metab,2007,9(3):276-281.
[23] Guzman E,Singh N,Khan IA,et al. Left bundle branch block in type 2 diabetes mellitus:a sign of advanced cardiovascular involvement[J]. Ann Noninvasive Electrocardiol,2004,9(4):362-365.
[24] 韩雅玲. 替格瑞洛临床应用中国专家共识[J].中华心血管病杂志,2016,44(2):112-120.
[25] Rosset S,Müller O,Pruvot E,et al. Prolonged asystole after a loading dose of ticagrelor[J]. Ann Intern Med,2018,168(8):602-603.
[26] 李秀艳,张文锐,柳杨,等. 替格瑞洛致心律失常不良反应文献分析[J].中国医院药学杂志,2020,40(6):699-703.
[27] Tsushima T,Sahadevan J,Intini A. Syncope after percutaneous coronary intervention[J]. JAMA Cardiol,2019,4(11):1170-1171.
[28] de Maria E,Borghi A,Modonesi L,et al. Ticagrelor therapy and atrioventricular block:do we need to worry?[J]. World J Clin Cases,2017,5(5):178-182.
[29] Yurtdas M,Ozdemir M. Ticagrelor-associated conduction disorder: a case report and review of the literature[J]. Cardiol Res,2017,8(3):123-127.
[30] di Serafino L,Rotolo FL,Boggi A,et al. Potential additive effects of ticagrelor,ivabradine,and carvedilol on sinus node[J]. Case Rep Cardiol,2014,2014:932595.
[31] 袁吉祥,张保和,刘玮. 替格瑞洛致高度房室阻滞合并心室停搏一例[J].中国循环杂志,2019,34(10):1025-1027.
[32] Goldberg A,Rosenfeld I,Nordkin I,et al. Life-threatening complete atrioventricular block associated with ticagrelor therapy[J]. Int J Cardiol,2015,182:379-380.
[33] Goldberg A,Rosenfeld I,Nordkin I,et al. Ticagrelor therapy in patients with advanced conduction disease:is it really safe?[J]. Int J Cardiol,2016,202:948-949.
[34] ?nlü M,Demirkol S,Yildirim AO,et al. Atrioventricular block associated with ticagrelor therapy may require permanent pacemaker[J]. Int J Cardiol,2016,202:946-947.
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