[1]王晓妍 崔炜.替格瑞洛治疗急性冠脉综合征时引起缓慢性心律失常的研究进展[J].心血管病学进展,2021,(7):642-644.[doi:10.16806/j.cnki.issn.1004-3934.2021.07.016]
 WANG Xiaoyan,CUI Wei.Bradyarrhythmia Caused by Ticagrelor in Treatment of Acute Coronary Syndrome[J].Advances in Cardiovascular Diseases,2021,(7):642-644.[doi:10.16806/j.cnki.issn.1004-3934.2021.07.016]
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替格瑞洛治疗急性冠脉综合征时引起缓慢性心律失常的研究进展()
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《心血管病学进展》[ISSN:51-1187/R/CN:1004-3934]

卷:
期数:
2021年7期
页码:
642-644
栏目:
出版日期:
2021-07-25

文章信息/Info

Title:
Bradyarrhythmia Caused by Ticagrelor in Treatment of Acute Coronary Syndrome
作者:
王晓妍 崔炜
河北医科大学第二医院心内科?河北省心脑血管病研究所心内科,河北 石家庄 050000)
Author(s):
WANG XiaoyanCUI Wei
(Department of CardiologyThe Second Hospital of Hebei Medical University and Institute of Cardiocerebrovascular Disease of Hebei ProvinceShijiazhuang 050000HebeiChina)
关键词:
替格瑞洛急性冠脉综合征缓慢性心律失常
Keywords:
TicagrelorAcute coronary syndromeBradyarrhythmia
DOI:
10.16806/j.cnki.issn.1004-3934.2021.07.016
摘要:
替格瑞洛属于新型P2Y12受体强效拮抗药,对二磷酸腺苷诱导的血小板聚集反应能产生呈浓度依赖和可逆的抑制作用,在临床上作为常用的抗血小板药物被广泛用于治疗急性冠脉综合征。在替格瑞洛管理急性冠脉综合征患者过程中发生缓慢性心律失常不良反应的可能性不大,但一旦发生有可能是致命性的。现重点阐述替格瑞洛在治疗急性冠脉综合征时缓慢性心律失常的发生率、机制、可能的危险因素、特点、干预及转归等方面的国内外研究进展。
Abstract:
Ticagrelor is a new potent antagonist of P2Y12 receptor,which has a concentration-related and reversible inhibitory effect on the platelet aggregation response induced by adenosine diphosphate. As a commonly used antiplatelet drug, it is widely used in the treatment of acute coronary syndrome. The incidence of bradyarrhythmia in patients with acute coronary syndrome treated with ticagrelor is low,but it may be fatal if it occurs. This article focuses on the research progress of incidence,mechanism,possible risk factors,characteristics,intervention and outcome of bradyarrhythmia by ticagrelor in the treatment of acute coronary syndrome at home and abroad

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更新日期/Last Update: 2021-09-10