[1]韩雅洁 范小倩 巩彩霞 赵子龙 乔成栋.致心律失常性左室心肌病的研究进展[J].心血管病学进展,2021,(4):342-346.[doi:10.16806/j.cnki.issn.1004-3934.2021.04.013]
 HAN Yajie,FAN Xiaoqian,GONG Caixia,et al.Arrhythmogenic Left Ventricular Cardiomyopathy[J].Advances in Cardiovascular Diseases,2021,(4):342-346.[doi:10.16806/j.cnki.issn.1004-3934.2021.04.013]
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致心律失常性左室心肌病的研究进展()
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《心血管病学进展》[ISSN:51-1187/R/CN:1004-3934]

卷:
期数:
2021年4期
页码:
342-346
栏目:
综述
出版日期:
2021-04-25

文章信息/Info

Title:
Arrhythmogenic Left Ventricular Cardiomyopathy
作者:
韩雅洁1 范小倩1 巩彩霞1 赵子龙1 乔成栋2
(1.兰州大学第一临床医学院,甘肃 兰州 7300002.兰州大学第一医院老年病科,甘肃 兰州 730000)
Author(s):
HAN Yajie1FAN Xiaoqian1GONG Caixia1ZHAO Zilong1QIAO Chengdong2
(The First Clinical Medical College of Lanzhou University,Lanzhou 730000,Gansu,China2.Department of Geriatrics ,The First Hospital of Lanzhou University,Lanzhou 730000,Gansu,China)
关键词:
致心律失常性左室心肌病发病机制流行病学诊断治疗
Keywords:
Arrhythmogenic left ventricular cardiomyopathy Pathogenesis Epidemiology Diagnosis Treatment
DOI:
10.16806/j.cnki.issn.1004-3934.2021.04.013
摘要:
致心律失常性左室心肌病是以左室心肌逐渐被脂肪和纤维组织替代的罕见遗传性心肌病,易发生危及生命的心律失常和心源性猝死。临床上主要依靠家族遗传病史、心电图、影像学和心内膜活检等作出诊断。有时起病隐匿,部分患者以猝死为首发症状,尸检后才作出诊断。治疗包括抗心律失常药物、治疗心力衰竭药物、导管射频消融、置入植入型心律转复除颤器以及心脏移植等。致心律失常性左室心肌病在病因、发病机制、诊断和治疗方面仍存在许多有待解决的问题,引起全社会的广泛关注。
Abstract:
Arrhythmogenic left ventricular cardiomyopathy (ALVC) is a rare hereditary cardiomyopathy in which the left ventricular myocardium is gradually replaced by fat and fibrous tissue. It is prone to life-threatening arrhythmias and sudden cardiac death (SCD). Clinical diagnosis mainly depends on family genetic history,electrocardiogram,imaging,endocardial biopsy and so on. Sometimes the onset is insidious,some patients have sudden death as the first symptom and the diagnosis is made after autopsy. Treatment includes antiarrhythmic drugs,drugs for heart failure,radiofrequency catheter ablation,implantable cardioverter defibrillator (ICD),heart transplantation and so on. There are still many problems to be solved in the etiology,pathogenesis,diagnosis and treatment of ALVC,which has aroused widespread concern of the whole society.

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备注/Memo

备注/Memo:
通信作者:乔成栋,E-mail:qcd2000@163.com 收稿时间:2020-09-16
更新日期/Last Update: 2021-07-01