[1]欧阳运峰 李皇庆 李璐 阳军.脂蛋白a:动脉粥样硬化性心血管疾病防治新靶点[J].心血管病学进展,2022,(8):731-734.[doi:10.16806/j.cnki.issn.1004-3934.2022.08.016]
 OUYANG Yunfeng,LI Huangqing,LI Lu,et al.Lipoprotein A:a New Target for Prevention and Treatment of Atherosclerotic Cardiovascular Disease[J].Advances in Cardiovascular Diseases,2022,(8):731-734.[doi:10.16806/j.cnki.issn.1004-3934.2022.08.016]
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《心血管病学进展》[ISSN:51-1187/R/CN:1004-3934]

卷:
期数:
2022年8期
页码:
731-734
栏目:
综述
出版日期:
2022-08-25

文章信息/Info

Title:
Lipoprotein A:a New Target for Prevention and Treatment of Atherosclerotic Cardiovascular Disease
作者:
欧阳运峰 李皇庆 李璐 阳军
(湖南师范大学第一附属医院心血管内科,湖南 长沙 410005)
Author(s):
OUYANG YunfengLI HuangqingLI LuYANG Jun
(Department of Cardiology,The Affiliated Hospital of Hunan Normal University,Changsha 410005,Hunan,China)
关键词:
脂蛋白a动脉粥样硬化性心血管疾病治疗
Keywords:
Lipoprotein a A therosclerotic cardiovascular disease Treatment
DOI:
10.16806/j.cnki.issn.1004-3934.2022.08.016
摘要:
当前流行病学、遗传学及临床相关研究均证实脂蛋白a[Lp(a)]与动脉粥样硬化性心血管疾病的发生发展密切相关,Lp(a)作为动脉粥样硬化性心血管疾病风险增加的独立危险因素,二者之间存在因果关系。现主要探讨Lp(a)在动脉粥样硬化性心血管疾病中的作用及Lp(a)治疗药物的最新进展。
Abstract:
Current epidemiological,genetic and clinical studies have confirmed that lipoprotein a[Lp(a)] is closely related to the occurrence and development of atherosclerotic cardiovascular disease (ASCVD). Lp(a) is an independent risk factor for the increase of ASCVD risk,and there is a causal relationship between them. This review mainly discusses the role of Lp(a) in atherosclerotic cardiovascular disease and the latest progress of Lp(a) therapeutic drugs.

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备注/Memo

备注/Memo:
基金项目:2022年湖南省中医药科研计划(D2022097);2019年湖南省研究生科研创新项目(CX20190407)
通信作者:阳军,E-mail:yangj523@163.com
更新日期/Last Update: 2022-10-08