[1]石玉姣 熊双 刘春秋 杨晨光 董国菊 刘剑刚.射血分数保留性心力衰竭潜在的分子机制及治疗靶点[J].心血管病学进展,2022,(5):423-427.[doi:10.16806/j.cnki.issn.1004-3934.2022.05.010]
 SHI Yujiao,XIONG Shuang,LIU Chunqiu,et al.Potential Molecular Mechanisms and Therapeutic Target in Heart Failure with Preserved Ejection Fraction[J].Advances in Cardiovascular Diseases,2022,(5):423-427.[doi:10.16806/j.cnki.issn.1004-3934.2022.05.010]
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射血分数保留性心力衰竭潜在的分子机制及治疗靶点()
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《心血管病学进展》[ISSN:51-1187/R/CN:1004-3934]

卷:
期数:
2022年5期
页码:
423-427
栏目:
出版日期:
2022-05-25

文章信息/Info

Title:
Potential Molecular Mechanisms and Therapeutic Target in Heart Failure with Preserved Ejection Fraction
作者:
石玉姣1 熊双1 刘春秋1 杨晨光1 董国菊12 刘剑刚12
(1.中国中医科学院研究生院,北京 100700;2.中国中医科学院西苑医院心血管内科,北京 100091)
Author(s):
SHI Yujiao1XIONG Shuang 1 LIU Chunqiu1YANG Chenguang1 DONG Guoju12 LIU Jiangang12
(1.Graduate School of Chinese Academy of Traditional Chinese Medicine,Beijing 100700,China; 2. Xiyuan Hospital of Chinese Academy of Traditional Chinese Medicine,Beijing 100091,China)
关键词:
心力衰竭射血分数保留性心力衰竭一氧化氮转化生长因子β微血管
Keywords:
Heart failure Heart failure with preserved ejection fraction Nitric oxideTransforming growth factor- Microvessel
DOI:
10.16806/j.cnki.issn.1004-3934.2022.05.010
摘要:
射血分数保留性心力衰竭是近年来心力衰竭最常见的形式之一。由于其病理生理机制复杂,导致治疗选择有限,且预后不佳。目前,研究者们普遍认为合并症诱发的全身慢性炎症可能是驱动射血分数保留性心力衰竭患者发生左心室不良重塑及舒张功能障碍的关键所在。因此了解这种发病模式潜在的调控机制,有利于探索有效的治疗方法。
Abstract:
Heart failure with preserved ejection fraction(HFpEF) has become one of the most common types of heart failure in recent years. Due to the complex pathophysiological mechanism,the choice of therapy is limited and the prognosis is poor. At present,experts believe that comorbidity-induced systemic chronic inflammation is the primary cause of abnormal left ventricular remodeling and diastolic dysfunction in HFpEF patients. Therefore,understanding the potential regulatory mechanism of this pathogenesis is conducive to explore effective treatment methods

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更新日期/Last Update: 2022-06-30