[1]游月婷 黄刚 张小刚 张亚丽 邓自刚 屈树新 靳忠民 徐俊波.心力衰竭动物建模的进展[J].心血管病学进展,2021,(12):1105-1109.[doi:10.16806/j.cnki.issn.1004-3934.2021.12.012]
 YOU YuetingHUANG Gang,ZHANG Xiaogang,ZHANG Yali,et al.Animal Models Establishment of Heart Failure[J].Advances in Cardiovascular Diseases,2021,(12):1105-1109.[doi:10.16806/j.cnki.issn.1004-3934.2021.12.012]
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《心血管病学进展》[ISSN:51-1187/R/CN:1004-3934]

卷:
期数:
2021年12期
页码:
1105-1109
栏目:
综述
出版日期:
2021-12-25

文章信息/Info

Title:
Animal Models Establishment of Heart Failure
作者:
游月婷1 黄刚1 张小刚2 张亚丽2 邓自刚3 屈树新4 靳忠民2 徐俊波1
(1. 西南交通大学医学院 西南交通大学附属医院 成都市第三人民医院心内科,四川 成都 610031;2. 西南交通大学机械工程学院,四川 成都 610031;3. 西南交通大学牵引动力国家重点实验室,四川 成都 610031;4. 西南交通大学材料科学与工程学院,四川 成都 610031)
Author(s):
YOU Yueting1HUANG Gang1 ZHANG Xiaogang2 ZHANG Yali2 DENG Zigang3 QU Shuxin4 JIN Zhongmin2 XU Junbo1
(1.School of Medicine,Southwest Jiaotong University,Affiliated Hospital of Southwest Jiaotong University,Department of Cardiology,The Third Peoples Hospital of Chengdu,Chengdu 610031,Sichuan,China; 2. School of Mechanical Engineering,Southwest Jiaotong University,Chengdu 610031,Sichuan,China; 3. State Key Laborary of Traction Power,Southwest Jiaotong University,Chengdu 610031,Sichuan,China; 4. School of Materials Science and Engineering,Southwest Jiaotong University,Chengdu 610031,Sichuan,China)
关键词:
心力衰竭动物模型制作原理临床应用
Keywords:
Heart failureAnimal modelsProduction principlesClinical applications
DOI:
10.16806/j.cnki.issn.1004-3934.2021.12.012
摘要:
心力衰竭是一组复杂临床综合征,是多种心脏疾病的严重表现或终末阶段,其发病率和病死率逐年增,严重危害着人类的身体健康。心力衰竭的发病机制和干预治疗仍需进一步的研究,建立成熟稳定的动物模是研究前提。对常用的各种心力衰竭动物模的制作原理和优缺点进行归纳整理,并例举各模的临床应用,给研究者在根据研究目的选择不同动物模时提供参考。
Abstract:
Heart failure is a kind of complex clinical syndromewhich is a serious manifestation or terminal stage of various heart diseases. Its morbidity and fatality rate are increasing year by year,which seriously endanger human health. The pathogenesis and intervention of heart failure still need further research,which require the establishment of mature and stable animal models. This review summaries the manufacturing principles,advantages and disadvantages of common animal models of heart failure,and lists the clinical applications of each model to provide studies with references when choosing different animal models.

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备注/Memo

备注/Memo:
基金项目:成都市科技局技术创新研发项目ENVISION研究(2019-YF05-00523-SN),西南交通大学医工结合培育专项重点项目(2682021ZTPY026)
通信作者:徐俊波,Email:xujunbo2000@sina.com?/div>
收稿时间:2021-07-22
更新日期/Last Update: 2022-01-07