[1]杨宜恒 郑振中.钠-葡萄糖协同转运蛋白2抑制剂对于未合并2型糖尿病的心力衰竭患者治疗的研究进展[J].心血管病学进展,2021,(12):1093-1095,1109.[doi:10.16806/j.cnki.issn.1004-3934.2021.12.009]
 YANG Yiheng,ZHENG Zhenzhong.Treatment of Sodium-Glucose Co-Transporter 2 Inhibitor in Patients with Heart Failure without Type 2 Diabetes[J].Advances in Cardiovascular Diseases,2021,(12):1093-1095,1109.[doi:10.16806/j.cnki.issn.1004-3934.2021.12.009]
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钠-葡萄糖协同转运蛋白2抑制剂对于未合并2型糖尿病的心力衰竭患者治疗的研究进展()
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《心血管病学进展》[ISSN:51-1187/R/CN:1004-3934]

卷:
期数:
2021年12期
页码:
1093-1095,1109
栏目:
综述
出版日期:
2021-12-25

文章信息/Info

Title:
Treatment of Sodium-Glucose Co-Transporter 2 Inhibitor in Patients with Heart Failure without Type 2 Diabetes
作者:
杨宜恒 郑振中
(南昌大学第一附属医院心内科,江西 南昌 330006)
Author(s):
YANG Yiheng ZHENG Zhenzhong
(Department of Cardiology,the First Affiliated Hospital of Nanchang University,Nanchang 330006 ,Jiangxi,China)
关键词:
钠-葡萄糖协同转运蛋白2抑制剂心力衰竭治疗
Keywords:
Sodium-glucose co-transporter 2 inhibitorHeart failureTreatment
DOI:
10.16806/j.cnki.issn.1004-3934.2021.12.009
摘要:
钠-葡萄糖协同转运蛋白2(SGLT2)抑制剂是一种新型降糖药物。已有研究表明它具有降低合并2型糖尿病的心力衰竭患者的住院率和死亡率的作用,这是其他降糖药所没有的功能。在不出现明显低血糖的情况下,SGLT2抑制剂对于未合并2型糖尿病的心力衰竭患者的使用是否也能获得相同的收益仍不清楚。现就SGLT2抑制剂对于未合并2型糖尿病的心力衰竭患者的临床疗效以及改善心力衰竭可能的机制进行综述。
Abstract:
sodium-glucose co-transporter 2(SGLT2) inhibitor are a new type of hypoglycemic drugs. It has been shown to reduce hospitalization rates and mortality in heart failure patients with type 2 diabetes which other hypoglycemic agents do not. It is not clear whether SGLT2 inhibitor will yield the same benefit for use in patients with heart failure without type 2 diabetes in the absence of significant hypoglycemia. This article reviews the possible mechanisms of clinical efficacy and improving heart failure in patients with heart failure without type 2 diabetes.

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备注/Memo

备注/Memo:
基金项目:江西省自然科学基金项目(20202ACBL206002)
通信作者:郑振中,E-mail:greateful@163.com?/div>
收稿日期:2021-06-17
更新日期/Last Update: 2022-01-07