[1]李天宇 郁志明.微RNA——主动脉夹层的潜在诊断标志物和治疗靶点[J].心血管病学进展,2025,(2):137.[doi:10.16806/j.cnki.issn.1004-3934.2025.02.010]
 LI Tianyu,YU Zhiming.MicroRNAA Potential Diagnostic Marker and Therapeutic Target for Aortic Dissection[J].Advances in Cardiovascular Diseases,2025,(2):137.[doi:10.16806/j.cnki.issn.1004-3934.2025.02.010]
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微RNA——主动脉夹层的潜在诊断标志物和治疗靶点()
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《心血管病学进展》[ISSN:51-1187/R/CN:1004-3934]

卷:
期数:
2025年2期
页码:
137
栏目:
综述
出版日期:
2025-02-25

文章信息/Info

Title:
MicroRNAA Potential Diagnostic Marker and Therapeutic Target for Aortic Dissection
作者:
李天宇 郁志明
(南京医科大学附属无锡人民医院心血管内科,江苏 无锡 214023)
Author(s):
LI TianyuYU Zhiming
(Department of Cardiology,Wuxi People’s Hospital Affiliated to Nanjing Medical University,Wuxi 214023,Jiangsu,China)
关键词:
主动脉夹层微RNA调控机制血管平滑肌细胞
Keywords:
Aortic dissectionMicroRNARegulation mechanismVascular smooth muscle cell
DOI:
10.16806/j.cnki.issn.1004-3934.2025.02.010
摘要:
主动脉夹层(AD),亦称AD动脉瘤,其发病机制尚未完全阐明。近年来,越来越多的研究揭示了微RNA(miRNA)与AD的发病机制密切相关。然而,目前关于miRNA与AD之间关系的研究相对较少,且研究方法较为单一,这限制了miRNA作为生物学标志物和治疗药物的潜力。现旨在探讨miRNA与AD发病机制的最新进展,以期发现能诊断AD的生物学标志物,并为AD治疗药物的开发提供科学依据。
Abstract:
Aortic Dissection (AD),also known as aortic dissection aneurysm,and its pathogenesis is not fully understood. In recent years,an increasing amount of research has revealed that microRNAs (miRNAs) are closely related to the pathogenesis of AD. However,there is currently relatively little research on the relationship between miRNA and AD,and the research methods are relatively single,which limits the potential of miRNA as a biomarker and therapeutic drug . This review aims to explore the latest advances in miRNA and the pathogenesis of AD,in order to discover biological markers that can diagnose AD and provide scientific basis for the development of therapeutic drugs for AD.

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更新日期/Last Update: 2025-03-11