[1]王超 须民欣 谢清梦 李丹 李凤 余思芸 卢遵曾健吴镜谢江.儿童高原肺水肿的研究进展[J].心血管病学进展,2024,(10):918.[doi:10.16806/j.cnki.issn.1004-3934.2024.10.011]
 WANG Chao,XU Minxin,XIE Qingmeng,et al.High Altitude Pulmonary Edema in Children[J].Advances in Cardiovascular Diseases,2024,(10):918.[doi:10.16806/j.cnki.issn.1004-3934.2024.10.011]
点击复制

儿童高原肺水肿的研究进展()
分享到:

《心血管病学进展》[ISSN:51-1187/R/CN:1004-3934]

卷:
期数:
2024年10期
页码:
918
栏目:
综述
出版日期:
2024-10-25

文章信息/Info

Title:
High Altitude Pulmonary Edema in Children
作者:
王超13 须民欣 1 谢清梦3 李丹 3 李凤 1 余思芸 1 卢遵1曾健1吴镜1谢江2
(1.西南交通大学附属医院 成都市第三人民医院 老年医学国际医疗中心,四川 成都 610031;2.西南交通大学附属医院 成都市第三人民医院儿科,四川 成都 610031;3.理塘县人民医院 康南急救中心,四川 甘孜藏族自治州 624300)
Author(s):
WANG Chao13XU Minxin1XIE Qingmeng3LI Dan3LI Feng1YU Siyun1LU Zun1ZENG Jian1WU Jing1XIE Jiang2
(1.Department of Geriatrics and International Medical Center,The Affiliated Hospital of Southwest Jiaotong University,The Third Peoples Hospital of Chengdu,Chengdu 6100 31,Sichuan,China;2.Department of Paediatrics,The Affiliated Hospital of Southwest Jiaotong University,The Third Peoples Hospital of Chengdu,Chengdu 610031,Sichuan,China;3.Litang County People’s Hospital,Kangnan Emergency Center,Ganzi Tibetan Autonomous Prefecture 624300,, Sichuan,China)
关键词:
儿童高原肺水肿急性高原病高海拔
Keywords:
ChildrenHigh altitude pulmonary edemaAcute high altitude sicknessHigh altitude
DOI:
10.16806/j.cnki.issn.1004-3934.2024.10.011
摘要:
虽然进入高海拔地区儿童高原肺水肿的患病率在逐年增加,但仍未引起广泛的重视。儿童的心血管系统在高海拔环境下会经历一系列生理变化以适应低氧和低气压环境,这些变化可能会导致高原肺水肿的发生。现总结儿童在高海拔地区活动时高原肺水肿的流行病学、发病机制、高危因素、临床表现、预防措施和治疗方法,以期减轻HAPE对进入高海拔地区儿童的影响,并引起对儿童高原肺水肿的重视及预防。
Abstract:
Although the prevalence of high altitude pulmonary edema(HAPE) in children entering high altitude is increasing yearly,it has not received widespread attention. The cardiovascular system of children undergoes a series of physiological changes to adapt to the hypoxic and hypobaric environment at high altitude,but these changes may contribute to the development of HAPE. The article summarises the epidemiology,pathogenesis,risk factors,clinical manifestations,preventive measures and treatment of HAPE in children when they are active at high altitude. In order to mitigate the effects of HAPE on children who are coming to high altitude , and to draw attention to and prevent HAPE in children.

参考文献/References:

[1].Santos-Martínez LE,Gómez-Tejada RA,Murillo-Jauregui CX,et al. [Chronic exposure to altitude. Clinical characteristics and diagnosis] [J]. Arch Cardiol Mex,2021,91(4):500-507.
[2].Luo Y,Yang X,Gao Y. Strategies for the prevention of acute mountain sickness and treatment for large groups making a rapid ascent in China[J]. Int J Cardiol,2013,169(2):97-100.
[3].Gudbjartsson T,Sigurdsson E,Gottfredsson M,et al. [High altitude illness and related diseases-a review] [J]. Laeknabladid,2019,105(11):499-507.
[4].Luks AM,Beidleman BA,Freer L,et al. Wilderness Medical Society Clinical Practice Guidelines for the Prevention,Diagnosis,and Treatment of Acute Altitude Illness:2024 Update[J]. Wilderness Environ Med,2024,35(1_suppl):2S-19S.
[5].Yaron M,Niermeyer S,Lindgren KN,et al. Evaluation of diagnostic criteria and incidence of acute mountain sickness in preverbal children [J]. Wilderness Environ Med,2002,13(1):21-26.
[6].Pradhan S,Yadav S,Neupane P,et al. Acute mountain sickness in children at 4380 meters in the Himalayas[J]. Wilderness Environ Med,2009,20(4):359-363.
[7].Theis MK,Honigman B,Yip R,et al. Acute mountain sickness in children at 2835 meters [J]. Am J Dis Child,1993,147(2):143-145.
[8].Dallimore J,Rowbotham EC. Incidence of acute mountain sickness in adolescents[J]. Wilderness Environ Med,2009,20(3):221-224.
[9].Moraga FA,Pedreros CP,Rodríguez CE. Acute mountain sickness in children and their parents after rapid ascent to 3500 m(Putre,Chile)[J]. Wilderness Environ Med,2008,19(4):287-292.
[10].Chan CW,Lin YC,Chiu YH,et al. Incidence and risk factors associated with acute mountain sickness in children trekking on Jade Mountain ,Taiwan[J]. J Travel Med,2016,23(1):tav008.
[11].Bloch J,Duplain H,Rimoldi SF,et al. Prevalence and time course of acute mountain sickness in older children and adolescents after rapid ascent to 3450 meters [J]. Pediatrics,2009,123(1):1-5.
[12].Rexhaj E,Garcin S,Rimoldi SF,et al. Reproducibility of acute mountain sickness in children and adults:a prospective study [J]. Pediatrics,2011,127(6):e1445-e1448.
[13].Ucrós S,Aparicio C,Castro-Rodriguez JA,et al. High altitude pulmonary edema in children:a systematic review [J]. Pediatr Pulmonol,2023,58(4):1059-1067.
[14].Rieger M,Algaze I,Rodriguez-Vasquez A,et al. Kids with altitude:acute mountain sickness and changes in body mass and total body water in children travelling to 3800 m[J]. Wilderness Environ Med,2022,33(1):33-42.
[15].Hurtado A,Escudero E,Pando J,et al. Cardiovascular and renal effects of chronic exposure to high altitude [J]. Nephrol Dial Transplant,2012,27(Suppl 4):iv11-iv16.
[16].Ostadal B,Kolar F. Cardiac adaptation to chronic high-altitude hypoxia:beneficial and adverse effects[J]. Respir Physiol Neurobiol,2007,158(2-3):224-236.
[17].Kriemler S,Radtke T,Bürgi F,et al. Short-term cardiorespiratory adaptation to high altitude in children compared with adults[J]. Scand J Med Sci Sports,2016,26(2):147-155.
[18].Lang M,Vizcaíno-Mu?oz G,Jopia P,et al. Physiological responses at rest and exercise to high altitude in lowland children and adolescents [J]. Life(Basel),2021,11(10):1009.
[19].Naeije R. Physiological adaptation of the cardiovascular system to high altitude[J]. Prog Cardiovasc Dis,2010,52(6):456-466.
[20].Yaron M,Niermeyer S,Lindgren KN,et al. Physiologic response to moderate altitude exposure among infants and young children[J]. High Alt Med Biol,2003,4(1):53-59.
[21].Garlick V,O’Connor A,Shubkin CD. High-altitude illness in the pediatric population:a review of the literature on prevention and treatment[J]. Curr Opin Pediatr,2017,29(4):503-509.
[22].Basnyat B,Gertsch JH,Holck PS,et al. Acetazolamide 125 mg BD is not significantly different from 375 mg BD in the prevention of acute mountain sickness:the prophylactic acetazolamide dosage comparison for efficacy (PACE) trial[J]. High Alt Med Biol,2006,7(1): 17-27.
[23].Scherrer U,Rexhaj E,Jayet PY,et al. New insights in the pathogenesis of high-altitude pulmonary edema [J]. Prog Cardiovasc Dis,2010,52(6):485-492.
[24].Asseri AA,Asiri ?A,Alwabel HH,et al. Severe acute reentry high altitude pulmonary edema in pediatric patients:report of three cases and literature review[J]. Turk J Pediatr,2022,64(2):400-407.
[25].Rimoldi SF,Rexhaj E,Duplain H,et al. Acute and chronic altitude-induced cognitive dysfunction in children and adolescents [J]. J Pediatr,2016,169:238-243.
[26].Chao CC,Chen LH,Lin YC,et al. Impact of a 3-day high-altitude trek on Xue Mountain (3886 m) ,Taiwan,on the emotional states of children:a prospective observational study[J]. High Alt Med Biol,2019,20(1):28-34.
[27].Cheng FY,Jeng MJ,Lin YC,et al. Incidence and severity of acute mountain sickness and associated symptoms in children trekking on Xue Mountain ,Taiwan[J]. PLoS One,2017,12(8):e0183207.
[28].Giesenhagen AM,Ivy DD,Brinton JT,et al. High altitude pulmonary edema in children:a single referral center evaluation [J].J Pediatr,2019,210:106-111.
[29].Southard A,Niermeyer S,Yaron M. Language used in Lake Louise Scoring System underestimates symptoms of acute mountain sickness in 4- to 11-year-old children[J]. High Alt Med Biol,2007,8(2):124-130.
[30].Eichstaedt CA,Mairb?url H,Song J,et al. Genetic predisposition to high-altitude pulmonary edema[J]. High Alt Med Biol,2020,21(1):28-36.
[31].Kelly TD,Meier M,Weinman JP,et al. High-altitude pulmonary edema in Colorado children:a cross-sectional survey and retrospective review [J]. High Alt Med Biol,2022,23(2):119-124.
[32].Coustet B,Lhuissier FJ,Vincent R,et al. Electrocardiographic changes during exercise in acute hypoxia and susceptibility to severe high-altitude illnesses[J]. Circulation,2015,131(9):786-794.
[33].Ramchandani R,Zhou Z,Parodi JB,et al. A systematic review of electrocardiographic changes in populations temporarily ascending to high altitudes[J]. Curr Probl Cardiol,2023,48(5):101630.

相似文献/References:

[1]刘颖,袁美锦.儿童与青少年心脏性猝死的病因和预防[J].心血管病学进展,2019,(6):935.[doi:10.16806/j.cnki.issn.1004-3934.2019.06.024]
 LIU Ying,YUAN Meijin.Causes and Prevention of Sudden Cardiac Death in Children and Adolescents[J].Advances in Cardiovascular Diseases,2019,(10):935.[doi:10.16806/j.cnki.issn.1004-3934.2019.06.024]
[2]罗芩 何庆.TNF凝集素样结构域:高原肺水肿药物治疗新选择罗芩 何庆2[J].心血管病学进展,2019,(9):1301.[doi:10.16806/j.cnki.issn.1004-3934.2019.00.030]
 LUO QinHE Qing.The Lectin-like Domain of TNF:New Drug Treatment Option for HAPE[J].Advances in Cardiovascular Diseases,2019,(10):1301.[doi:10.16806/j.cnki.issn.1004-3934.2019.00.030]
[3]马佳 陈肯 张宇清.儿童及青少年单纯收缩期高血压发病机制研究进展[J].心血管病学进展,2020,(4):392.[doi:10.16806/j.cnki.issn.1004-3934.2020.04.016]
 MA Jia,CHEN Ken,ZHANG Yuqing.The Pathogenesis of Isolated Systolic Hypertension in Children and Adolescents[J].Advances in Cardiovascular Diseases,2020,(10):392.[doi:10.16806/j.cnki.issn.1004-3934.2020.04.016]
[4]石树文 田雯.肠道微生物群与儿童川崎病[J].心血管病学进展,2020,(6):608.[doi:10.16806/j.cnki.issn.1004-3934.2020.06.012]
 SHI ShuwenTIAN Wen. Intestinal microbiota and children Kawasaki disease[J].Advances in Cardiovascular Diseases,2020,(10):608.[doi:10.16806/j.cnki.issn.1004-3934.2020.06.012]
[5]李祎 刘德敏.儿童对比剂肾病的研究进展[J].心血管病学进展,2021,(8):725.[doi:10.16806/j.cnki.issn.1004-3934.2021.08.013]
 LI Yi,LIU Demin.Contrast Induced Acute Kidney Injury In Children[J].Advances in Cardiovascular Diseases,2021,(10):725.[doi:10.16806/j.cnki.issn.1004-3934.2021.08.013]
[6]罗芩 何庆?/html>.腺苷2B受体激动剂对大鼠高原肺水肿的治疗作用[J].心血管病学进展,2021,(10):941.[doi:10.16806/j.cnki.issn.1004-3934.2021.10.019]
 LUO Qin,HE Qing.Therapeutic Effect of Adenosine 2B Receptor Agonist on High-Altitude Pulmonary Edema in Rats[J].Advances in Cardiovascular Diseases,2021,(10):941.[doi:10.16806/j.cnki.issn.1004-3934.2021.10.019]
[7]王蕊 赵鹏军.儿童肥厚型心肌病诊断方法及其对猝死风险评估的价值[J].心血管病学进展,2023,(8):681.[doi:10.16806/j.cnki.issn.1004-3934.2023.08.003]
 WANG Rui,ZHAO Pengjun.Diagnostic Methods of Hypertrophic Cardiomyopathy in Children and Its Value in Risk Assessment of Sudden Death[J].Advances in Cardiovascular Diseases,2023,(10):681.[doi:10.16806/j.cnki.issn.1004-3934.2023.08.003]
[8]李强强 顾虹.中国儿童肺动脉高压诊治现状[J].心血管病学进展,2024,(1):7.[doi:10.16806/j.cnki.issn.1004-3934.2024.01.003]
 LI Qiangqiang,GU Hong.Current Status of Diagnosis and Treatment of Pulmonary Hypertension in Chinese Children[J].Advances in Cardiovascular Diseases,2024,(10):7.[doi:10.16806/j.cnki.issn.1004-3934.2024.01.003]

更新日期/Last Update: 2024-11-01