[1]田师鹏,王立立,陈淑霞,等.维利西呱在心力衰竭方面的研究进展[J].心血管病学进展,2023,(7):602.[doi:10.16806/j.cnki.issn.1004-3934.202.07.007]
 TIAN Shipeng,AN Hui,CHEN Shuxia,et al.Clinical Research Progress of Vericiguat in Heart Failure?/html>[J].Advances in Cardiovascular Diseases,2023,(7):602.[doi:10.16806/j.cnki.issn.1004-3934.202.07.007]
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维利西呱在心力衰竭方面的研究进展()
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《心血管病学进展》[ISSN:51-1187/R/CN:1004-3934]

卷:
期数:
2023年7期
页码:
602
栏目:
综述
出版日期:
2023-07-25

文章信息/Info

Title:
Clinical Research Progress of Vericiguat in Heart Failure?/html>
作者:
田师鹏王立立陈淑霞谷剑安慧
(河北省人民医院心血管内科,河北 石家庄050051)
Author(s):
TIAN ShipengAN HuiCHEN ShuxiaGU JianWANG Lili
(Department of CardiologyHebei General HospitalShijiazhuang 050051HebeiChina)
关键词:
维立西呱心力衰竭可溶性鸟苷酸环化酶激动剂
Keywords:
VericiguatHeart failureSoluble guanylate cyclase stimulator
DOI:
10.16806/j.cnki.issn.1004-3934.202.07.007
摘要:
心力衰竭是各种心血管疾病的终末阶段,尽管目前以抑制交感神经和肾素-血管紧张素-醛固酮系统为基础的药物延缓了疾病的进展,但目前心力衰竭患者的预后仍不理想。可溶性鸟苷酸环化酶激动剂维利西呱是一种治疗心力衰竭的新型药物,其主要作用于一氧化氮-可溶性鸟苷酸环化酶-环磷酸鸟苷信号通路。现对可溶性鸟苷酸环化酶激动剂维利西呱在心力衰竭领域的最新研究进展作一简要综述。
Abstract:
Heart failure is the end stage of various cardiovascular diseases, and although current drugs based on sympathetic inhibition and the renin-angiotensin-aldosterone system have slowed the progression of the disease, the prognosis of patients with heart failure is still unsatisfactory. Soluble guanylate cyclase stimulator vericiguat is a novel drug for the treatment of heart failure, which mainly acts on the nitric oxide-soluble guanylate cyclase-cyclic guanosine monophosphate signaling pathway. A brief review of the latest research progress of the soluble guanylate cyclase stimulator vericiguat in the field of heart failure is presented.

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更新日期/Last Update: 2023-08-18