[1]安海英 涂建成.载脂蛋白B与非高密度脂蛋白胆固醇在ASCVD防控中的应用价值[J].心血管病学进展,2022,(9):803-807.[doi:10.16806/j.cnki.issn.1004-3934.2022.09.009]
 AN Haiying,TU Jiancheng.Application Value of Apolipoprotein B and Non-High-Density Lipoprotein Cholesterol in ASCVD Prevention and Control[J].Advances in Cardiovascular Diseases,2022,(9):803-807.[doi:10.16806/j.cnki.issn.1004-3934.2022.09.009]
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载脂蛋白B与非高密度脂蛋白胆固醇在ASCVD防控中的应用价值()
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《心血管病学进展》[ISSN:51-1187/R/CN:1004-3934]

卷:
期数:
2022年9期
页码:
803-807
栏目:
出版日期:
2022-09-25

文章信息/Info

Title:
Application Value of Apolipoprotein B and Non-High-Density Lipoprotein Cholesterol in ASCVD Prevention and Control
作者:
安海英 涂建成
(武汉大学中南医院检验科,湖北 武汉 430071)
Author(s):
AN HaiyingTU Jiancheng
(Medical Clinical Laboratory,Zhongnan Hospital Affiliated to Wuhan University,Wuhan 430071,Hubei,China)
关键词:
动脉粥样硬化性心血管疾病非高密度脂蛋白胆固醇载脂蛋白B
Keywords:
Atherosclerotic cardiovascular diseaseNon-high-density lipoprotein cholesterolApolipoprotein B
DOI:
10.16806/j.cnki.issn.1004-3934.2022.09.009
摘要:
动脉粥样硬化性心血管疾病(ASCVD)是一种严重威胁全人类健康并给社会带来沉重负担的疾病,脂代谢异常是公认的致病危险因素。近年来的研究提示,非高密度脂蛋白胆固醇(non-HDL-C)和载脂蛋白B(ApoB)在ASCVD的防控中有重要临床意义,需重点关注,众多指南均建议使用non-HDL-C或ApoB作为评估和管理ASCVD风险的替代或次要靶标。现通过综述non-HDL-C和ApoB在ASCVD中的最新研究进展,比较分析二者异同,以期明确二者的应用价值,从而为其临床应用提供参考。
Abstract:
Atherosclerotic cardiovascular disease(ASCVD) is a disease that seriously threatens the health of all human beings and brings a heavy burden to society. Abnormal lipid metabolism is a recognized risk factor. Recent studies have suggested that non-high-density lipoprotein cholesterol(non-HDL-C) and apolipoprotein B(ApoB) have important clinical significance in the prevention and control of ASCVD. Importantly,numerous guidelines recommend the use of non-HDL-C or apoB as an alternative or secondary target for assessing and managing ASCVD risk. This paper reviews the latest research progress of non-HDL-C and ApoB in ASCVD,and compares and analyzes the similarities and differences of the two,in order to clarify the application value of the two,so as to provide a reference for their clinical application.

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备注/Memo

备注/Memo:
收稿日期: 2022-05-09
更新日期/Last Update: 2022-10-24